Semimechanistic cell-cycle type-based pharmacokinetic/pharmacodynamic model of chemotherapy-induced neutropenic effects of diflomotecan under different dosing schedules.
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Towards Quantitative Systems Pharmacology Models of Chemotherapy-Induced Neutropenia.Bringing Model-Based Prediction to Oncology Clinical Practice: A Review of Pharmacometrics Principles and Applications.Camptothecin (CPT) and its derivatives are known to target topoisomerase I (Top1) as their mechanism of action: did we miss something in CPT analogue molecular targets for treating human disease such as cancer?Mathematical modeling of efficacy and safety for anticancer drugs clinical development.
P2860
Semimechanistic cell-cycle type-based pharmacokinetic/pharmacodynamic model of chemotherapy-induced neutropenic effects of diflomotecan under different dosing schedules.
description
2015 nî lūn-bûn
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2015年の論文
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2015年論文
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2015年論文
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2015年論文
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2015年論文
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2015年論文
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2015年论文
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2015年论文
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2015年论文
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name
Semimechanistic cell-cycle typ ...... er different dosing schedules.
@en
type
label
Semimechanistic cell-cycle typ ...... er different dosing schedules.
@en
prefLabel
Semimechanistic cell-cycle typ ...... er different dosing schedules.
@en
P50
P356
P1476
Semimechanistic cell-cycle typ ...... der different dosing schedules
@en
P2093
Elena Soto
Núria Buil-Bruna
P356
10.1124/JPET.115.223776
P407
P577
2015-05-06T00:00:00Z