Clustering of activating mutations in c-KIT's juxtamembrane coding region in canine mast cell neoplasms.
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CD117 immunoexpression in canine mast cell tumours: correlations with pathological variables and proliferation markersEvaluation of the kinase domain of c-KIT in canine cutaneous mast cell tumors.Canine and human gastrointestinal stromal tumors display similar mutations in c-KIT exon 11.Imatinib responsiveness in canine mast cell tumors carrying novel mutations of c-KIT exon 11.Beyond H&E: integration of nucleic acid-based analyses into diagnostic pathology.The role of c-KIT in tumorigenesis: evaluation in canine cutaneous mast cell tumors.FLT3: ITDoes matter in leukemia.Biology of gastrointestinal stromal tumors: KIT mutations and beyond.Immunohistochemical evaluation of AKT protein activation in canine mast cell tumoursIdentification of the two KIT isoforms and their expression status in canine hemangiosarcomas.Cutaneous mastocytosis with a mutation in the juxtamembrane domain of c-kit in a young laboratory beagle dog.Advances in the diagnosis and management of cutaneous mast cell tumours in dogs.Breed-predispositions to cancer in pedigree dogs.Concordance of c-kit mutational status in matched primary and metastatic cutaneous canine mast cell tumors at baselineGeneration and characterization of novel canine malignant mast cell line CL1.Molecular drug targets in myeloproliferative neoplasms: mutant ABL1, JAK2, MPL, KIT, PDGFRA, PDGFRB and FGFR1.Receptor tyrosine kinase inhibitors: molecularly targeted drugs for veterinary cancer therapy.The Relevance of CD117-Immunocytochemistry Staining Patterns to Mutational Exon-11 in c-kit Detected by PCR from Fine-Needle Aspirated Canine Mast Cell Tumor Cells.NI-1: a novel canine mastocytoma model for studying drug resistance and IgER-dependent mast cell activation.Biological effect of tyrosine kinase inhibitors on three canine mast cell tumor cell lines with various KIT statuses.H1-receptor antagonists terfenadine and loratadine inhibit spontaneous growth of neoplastic mast cells.Autoinhibition of the kit receptor tyrosine kinase by the cytosolic juxtamembrane region.A repressor sequence in the juxtamembrane domain of Flt-1 (VEGFR-1) constitutively inhibits vascular endothelial growth factor-dependent phosphatidylinositol 3'-kinase activation and endothelial cell migrationFunctional and phenotypic studies of two variants of a human mast cell line with a distinct set of mutations in the c-kit proto-oncogene.Inhibition of spontaneous receptor phosphorylation by residues in a putative alpha-helix in the KIT intracellular juxtamembrane region.Detection of c-kit mutations in canine mast cell tumors using fluorescent polyacrylamide gel electrophoresis.The use of KIT and tryptase expression patterns as prognostic tools for canine cutaneous mast cell tumors.Comparative Aspects of BRAF Mutations in Canine Cancers.Expression of the KIT protein (CD117) in primary cutaneous mast cell tumors of the dog.Expression of KIT receptor in feline cutaneous mast cell tumors.KIT-positive gastrointestinal stromal tumor in a 22-year-old male chimpanzee (Pan troglodites).Prevalence of exon 11 internal tandem duplications in the C-KIT proto-oncogene in Australian canine mast cell tumours.A study of mutations in the c-kit gene of 32 dogs with mastocytoma.Expression of c-kit proto-oncogene in canine mastocytoma: a kinetic study using real-time polymerase chain reaction.The use of COLD-PCR, DHPLC and GeneScanning for the highly sensitive detection of c-KIT somatic mutations in canine mast cell tumours.Canine subcutaneous mast cell tumors: cellular proliferation and KIT expression as prognostic indices.Gastrointestinal stromal tumors and leiomyomas in the dog: a histopathologic, immunohistochemical, and molecular genetic study of 50 cases.The tyrosine kinase inhibitor toceranib in feline injection site sarcoma: efficacy and side effects.
P2860
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P2860
Clustering of activating mutations in c-KIT's juxtamembrane coding region in canine mast cell neoplasms.
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
1999年论文
@zh
1999年论文
@zh-cn
name
Clustering of activating mutat ...... in canine mast cell neoplasms.
@en
type
label
Clustering of activating mutat ...... in canine mast cell neoplasms.
@en
prefLabel
Clustering of activating mutat ...... in canine mast cell neoplasms.
@en
P2093
P1476
Clustering of activating mutat ...... in canine mast cell neoplasms.
@en
P2093
P304
P356
10.1046/J.1523-1747.1999.00488.X
P407
P577
1999-02-01T00:00:00Z
P5875
P6179
1021569674