Purified soluble guanylyl cyclase expressed in a baculovirus/Sf9 system: stimulation by YC-1, nitric oxide, and carbon monoxide.
about
NO-independent stimulators and activators of soluble guanylate cyclase: discovery and therapeutic potentialNO-independent regulatory site of direct sGC stimulators like YC-1 and BAY 41-2272RNA splicing in regulation of nitric oxide receptor soluble guanylyl cyclaseExtending the translational potential of targeting NO/cGMP-regulated pathways in the CVSUnprecedented proximal binding of nitric oxide to heme: implications for guanylate cyclaseInterfacial residues promote an optimal alignment of the catalytic center in human soluble guanylate cyclase: heterodimerization is required but not sufficient for activity.Dissociation of nitric oxide from soluble guanylate cyclase and heme-nitric oxide/oxygen binding domain constructsNO-independent regulatory site on soluble guanylate cyclase.Release of nitric oxide from endothelial cells stimulated by YC-1, an activator of soluble guanylyl cyclaseThalidomide attenuates nitric oxide-driven angiogenesis by interacting with soluble guanylyl cyclase.Protective effects of YC-1 against glutamate induced PC12 cell apoptosis.YC-1 activation of human soluble guanylyl cyclase has both heme-dependent and heme-independent componentsTargeting the heme-oxidized nitric oxide receptor for selective vasodilatation of diseased blood vesselsCardiovascular actions of a novel NO-independent guanylyl cyclase stimulator, BAY 41-8543: in vivo studiesPharmacological actions of a novel NO-independent guanylyl cyclase stimulator, BAY 41-8543: in vitro studiesNO- and haem-independent activation of soluble guanylyl cyclase: molecular basis and cardiovascular implications of a new pharmacological principle.Cobinamides are novel coactivators of nitric oxide receptor that target soluble guanylyl cyclase catalytic domain.The alpha1 isoform of soluble guanylate cyclase regulates cardiac contractility but is not required for ischemic preconditioningHuman recombinant soluble guanylyl cyclase: expression, purification, and regulation.Modulating nitric oxide signaling in the CNS for Alzheimer's disease therapy.The chemistry and biology of soluble guanylate cyclase stimulators and activators.Non-nitric oxide based metallovasodilators: synthesis, reactivity and biological studies.Distinct molecular requirements for activation or stabilization of soluble guanylyl cyclase upon haem oxidation-induced degradation.Allostery in recombinant soluble guanylyl cyclase from Manduca sexta.A functional domain of the alpha1 subunit of soluble guanylyl cyclase is necessary for activation of the enzyme by nitric oxide and YC-1 but is not involved in heme binding.Activation of soluble guanylate cyclase causes relaxation of corpus cavernosum tissue: synergism of nitric oxide and YC-1.Insight into the rescue of oxidized soluble guanylate cyclase by the activator cinaciguat.Inhibition of platelet aggregation by carbon monoxide-releasing molecules (CO-RMs): comparison with NO donors.Pharmacology of the nitric oxide receptor, soluble guanylyl cyclase, in cerebellar cells.Role of heme oxygenase-carbon monoxide pathway in pathogenesis of cirrhotic cardiomyopathy in the rat.Dynamic change of heme environment in soluble guanylate cyclase and complexation of NO-independent drug agents with H-NOX domain.Identification of residues crucially involved in the binding of the heme moiety of soluble guanylate cyclase.Soluble guanylate cyclase crystal clear: 1st crystal structure of the wild-type human heterodimeric sGC catalytic domains and implications for activity.An enzyme-linked receptor mechanism for nitric oxide-activated guanylyl cyclase.Mechanisms underlying relaxation of rabbit aorta by BAY 41-2272, a nitric oxide-independent soluble guanylate cyclase activator.3',5'-cIMP as Potential Second Messenger in the Vascular Wall.Structure/function of the soluble guanylyl cyclase catalytic domain.Maprotiline Prevents Monocrotaline-Induced Pulmonary Arterial Hypertension in Rats
P2860
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P2860
Purified soluble guanylyl cyclase expressed in a baculovirus/Sf9 system: stimulation by YC-1, nitric oxide, and carbon monoxide.
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
1999年论文
@zh
1999年论文
@zh-cn
name
Purified soluble guanylyl cycl ...... ic oxide, and carbon monoxide.
@en
type
label
Purified soluble guanylyl cycl ...... ic oxide, and carbon monoxide.
@en
prefLabel
Purified soluble guanylyl cycl ...... ic oxide, and carbon monoxide.
@en
P2093
P356
P1476
Purified soluble guanylyl cycl ...... ic oxide, and carbon monoxide.
@en
P2093
Hoenicka M
Schröder H
Sirichoke T
P2888
P356
10.1007/S001090050292
P577
1999-01-01T00:00:00Z