Functional KCa3.1 K+ channels are required for human lung mast cell migration
about
The intermediate-conductance calcium-activated potassium channel KCa3.1 contributes to atherogenesis in mice and humansTRAM-34, a putatively selective blocker of intermediate-conductance, calcium-activated potassium channels, inhibits cytochrome P450 activityK(Ca)3.1 channel-blockade attenuates airway pathophysiology in a sheep model of chronic asthmaThe CD20 homologue MS4A4 directs trafficking of KIT toward clathrin-independent endocytosis pathways and thus regulates receptor signaling and recyclingCa(2+)-activated K(+) channel-3.1 blocker TRAM-34 attenuates airway remodeling and eosinophilia in a murine asthma model.Pathogenesis of allergic airway inflammation.Regulation of Ca2+ signaling with particular focus on mast cells.Ion channels regulating mast cell biology.Targeting potassium channels Kv1.3 and KC a 3.1: routes to selective immunomodulators in autoimmune disorder treatment?Systemic effects of ingested Lactobacillus rhamnosus: inhibition of mast cell membrane potassium (IKCa) current and degranulation.A novel FcεRIβ-chain truncation regulates human mast cell proliferation and survivalTransmembrane potential of GlyCl-expressing instructor cells induces a neoplastic-like conversion of melanocytes via a serotonergic pathway.Increased constitutive αSMA and Smad2/3 expression in idiopathic pulmonary fibrosis myofibroblasts is KCa3.1-dependent.Doxofylline: a promising methylxanthine derivative for the treatment of asthma and chronic obstructive pulmonary disease.The K+ channel KCa3.1 as a novel target for idiopathic pulmonary fibrosisHigh glucose induces CCL20 in proximal tubular cells via activation of the KCa3.1 channelHuman lung myofibroblast TGFβ1-dependent Smad2/3 signalling is Ca(2+)-dependent and regulated by KCa3.1 K(+) channelsIntegrin α9β1-mediated cell migration in glioblastoma via SSAT and Kir4.2 potassium channel pathwayThe Lymphocyte Potassium Channels Kv1.3 and KCa3.1 as Targets for Immunosuppression.Calcium-activated potassium channel KCa3.1 in lung dendritic cell migrationIntermediate-conductance calcium-activated potassium channel KCa3.1 and chloride channel modulate chemokine ligand (CCL19/CCL21)-induced migration of dendritic cells.Orai/CRACM1 and KCa3.1 ion channels interact in the human lung mast cell plasma membrane.KCa3.1 K+ Channel Expression and Function in Human Bronchial Epithelial CellsTherapeutic potential of KCa3.1 blockers: recent advances and promising trends.Lentiviral shRNA against KCa3.1 inhibits allergic response in allergic rhinitis and suppresses mast cell activity via PI3K/AKT signaling pathway.CRACM/Orai ion channel expression and function in human lung mast cellsThe alpha9beta1 integrin enhances cell migration by polyamine-mediated modulation of an inward-rectifier potassium channelIon channels in innate and adaptive immunityChemokines and their receptors as potential targets for the treatment of asthma.The mast cell and allergic diseases: role in pathogenesis and implications for therapy.Blockade of KCa3.1 ameliorates renal fibrosis through the TGF-β1/Smad pathway in diabetic miceKCa3.1: target and marker for cancer, autoimmune disorder and vascular inflammation?Functional KCa3.1 channels regulate steroid insensitivity in bronchial smooth muscle cellsK+ channel modulators for the treatment of neurological disorders and autoimmune diseasesPotassium channels keep mobile cells on the go.The K+ channels K(Ca)3.1 and K(v)1.3 as novel targets for asthma therapy.Exon skipping of FcεRIβ eliminates expression of the high-affinity IgE receptor in mast cells with therapeutic potential for allergy.miR-497-5p inhibits cell proliferation and invasion by targeting KCa3.1 in angiosarcoma.A role for ion channels in perivascular glioma invasion.Aromatic-aromatic interactions between residues in KCa3.1 pore helix and S5 transmembrane segment control the channel gating process.
P2860
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P2860
Functional KCa3.1 K+ channels are required for human lung mast cell migration
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Functional KCa3.1 K+ channels are required for human lung mast cell migration
@en
type
label
Functional KCa3.1 K+ channels are required for human lung mast cell migration
@en
prefLabel
Functional KCa3.1 K+ channels are required for human lung mast cell migration
@en
P2860
P356
P1433
P1476
Functional KCa3.1 K+ channels are required for human lung mast cell migration
@en
P2093
C E Brightling
P2860
P304
P356
10.1136/THX.2006.060319
P407
P577
2006-06-29T00:00:00Z