Synthesis, assembly, and intracellular transport of the platelet glycoprotein Ib-IX-V complex.
about
Specific heterodimer formation is a prerequisite for uroplakins to exit from the endoplasmic reticulumJuxtamembrane basic residues in glycoprotein Ibbeta cytoplasmic domain are required for assembly and surface expression of glycoprotein Ib-IX complex.Specific heteromeric association of four transmembrane peptides derived from platelet glycoprotein Ib-IX complexCys97-->Tyr mutation in the glycoprotein IX gene associated with Bernard-Soulier syndromeBiosynthesis and intracellular post-translational processing of normal and mutant platelet glycoprotein GPIb-IXBernard-Soulier syndrome: common ancestry in two African American families with the GP Ib alpha Leu129Pro mutation.Synthesis of GPIb beta with novel transmembrane and cytoplasmic sequences in a Bernard-Soulier patient resulting in GPIb-defective signaling in CHO cells.Molecular genetic analysis of a variant Bernard-Soulier syndrome due to compound heterozygosity for two novel glycoprotein Ibbeta mutations.Heat-shock protein gp96/grp94 is an essential chaperone for the platelet glycoprotein Ib-IX-V complex.The organizing principle of the platelet glycoprotein Ib-IX-V complex.Identification of a juxtamembrane mechanosensitive domain in the platelet mechanosensor glycoprotein Ib-IX complex.Signaling-mediated cooperativity between glycoprotein Ib-IX and protease-activated receptors in thrombin-induced platelet activationModel systems for platelet receptor shedding.Analysis of inter-subunit contacts reveals the structural malleability of extracellular domains in platelet glycoprotein Ib-IX complex.Modularity of the oncoprotein-like properties of platelet glycoprotein Ibalpha.Role of the transmembrane domain of glycoprotein IX in assembly of the glycoprotein Ib-IX complex.A palmitylated peptide derived from the glycoprotein Ib beta cytoplasmic tail inhibits platelet activation.Filamin A binding stabilizes nascent glycoprotein Ibalpha trafficking and thereby enhances its surface expression.The transmembrane domain of glycoprotein Ibbeta is critical to efficient expression of glycoprotein Ib-IX complex in the plasma membrane.A role for the actin cytoskeleton in the initiation and maintenance of store-mediated calcium entry in human platelets. Evidence for conformational coupling.
P2860
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P2860
Synthesis, assembly, and intracellular transport of the platelet glycoprotein Ib-IX-V complex.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
1998年论文
@zh
1998年论文
@zh-cn
name
Synthesis, assembly, and intra ...... glycoprotein Ib-IX-V complex.
@en
type
label
Synthesis, assembly, and intra ...... glycoprotein Ib-IX-V complex.
@en
prefLabel
Synthesis, assembly, and intra ...... glycoprotein Ib-IX-V complex.
@en
P2093
P2860
P356
P1476
Synthesis, assembly, and intra ...... glycoprotein Ib-IX-V complex.
@en
P2093
P2860
P304
31449-31454
P356
10.1074/JBC.273.47.31449
P407
P577
1998-11-01T00:00:00Z