DDX6 regulates sequestered nuclear CUG-expanded DMPK-mRNA in dystrophia myotonica type 1. - Wikidata - awgldk - TriplyDB

DDX6 regulates sequestered nuclear CUG-expanded DMPK-mRNA in dystrophia myotonica type 1.

DDX6 regulates sequestered nuclear CUG-expanded DMPK-mRNA in dystrophia myotonica type 1.

http://www.wikidata.org/entity/Q41002587

about

Mechanistic determinants of MBNL activity MBNL proteins and their target RNAs, interaction and splicing regulation.Reduction of toxic RNAs in myotonic dystrophies type 1 and type 2 by the RNA helicase p68/DDX5 MBNL Sequestration by Toxic RNAs and RNA Misprocessing in the Myotonic Dystrophy Brain Staufen1s role as a splicing factor and a disease modifier in Myotonic Dystrophy Type I.Identifying proteins that bind to specific RNAs - focus on simple repeat expansion diseases.Dual mechanisms regulate the nucleocytoplasmic localization of human DDX6.Molecular mechanisms in DM1 - a focus on foci.Myotonic dystrophy: approach to therapy.Can Human Pluripotent Stem Cell-Derived Cardiomyocytes Advance Understanding of Muscular Dystrophies?RNA toxicity and foci formation in microsatellite expansion diseases.Protein sequestration as a normal function of long noncoding RNAs and a pathogenic mechanism of RNAs containing nucleotide repeat expansions.Correction of GSK3β at young age prevents muscle pathology in mice with myotonic dystrophy type 1.DEAD-box helicase 6 (DDX6) is a new negative regulator for milk synthesis and proliferation of bovine mammary epithelial cells.Regulatory Role of RNA Chaperone TDP-43 for RNA Misfolding and Repeat-Associated Translation in SCA31.Repeat-associated non-AUG (RAN) translation and other molecular mechanisms in Fragile X Tremor Ataxia Syndrome.Human DNA Helicase B as a Candidate for Unwinding Secondary CGG Repeat Structures at the Fragile X Mental Retardation Gene.Small Molecules Which Improve Pathogenesis of Myotonic Dystrophy Type 1.

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DDX6 regulates sequestered nuclear CUG-expanded DMPK-mRNA in dystrophia myotonica type 1.

http://www.wikidata.org/entity/Q41002587

description

2014 nî lūn-bûn

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2014年の論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年论文

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2014年论文

@zh

2014年论文

@zh-cn

name

DDX6 regulates sequestered nuclear CUG-expanded DMPK-mRNA in dystrophia myotonica type 1.

@en

type

label

DDX6 regulates sequestered nuclear CUG-expanded DMPK-mRNA in dystrophia myotonica type 1.

@en

prefLabel

DDX6 regulates sequestered nuclear CUG-expanded DMPK-mRNA in dystrophia myotonica type 1.

@en

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Nucleic Acids Research

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DDX6 regulates sequestered nuclear CUG-expanded DMPK-mRNA in dystrophia myotonica type 1.

@en

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Christian K Damgaard

http://www.w3.org/2001/XMLSchema#string

Diana Andrejeva

http://www.w3.org/2001/XMLSchema#string

Lars Aagaard

http://www.w3.org/2001/XMLSchema#string

Olof J Pettersson

http://www.w3.org/2001/XMLSchema#string

Rune Thomsen

http://www.w3.org/2001/XMLSchema#string

Thomas G Jensen

http://www.w3.org/2001/XMLSchema#string

P2860

Translation repression in human cells by microRNA-induced gene silencing requires RCK/p54

The CELF family of RNA binding proteins is implicated in cell-specific and developmentally regulated alternative splicing

Multiple processing body factors and the ARE binding protein TTP activate mRNA decapping

Failure of MBNL1-dependent post-natal splicing transitions in myotonic dystrophy

A role for eIF4E and eIF4E-transporter in targeting mRNPs to mammalian processing bodies.

In vivo co-localisation of MBNL protein with DMPK expanded-repeat transcripts

Structural basis for RNA-duplex recognition and unwinding by the DEAD-box helicase Mss116p

The DEAD box helicase, Dhh1p, functions in mRNA decapping and interacts with both the decapping and deadenylase complexes.

TTP and BRF proteins nucleate processing body formation to silence mRNAs with AU-rich elements

RNA helicase p54 (DDX6) is a shuttling protein involved in nuclear assembly of stored mRNP particles

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7186-7200

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scholarly article

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10.1093/NAR/GKU352

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11

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42

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2014-05-03T00:00:00Z

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262050980

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24792155

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4066779

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