Anthrax lethal factor cleaves the N-terminus of MAPKKs and induces tyrosine/threonine phosphorylation of MAPKs in cultured macrophages.
about
Gram-positive and gram-negative bacterial toxins in sepsis: a brief reviewBinding of anthrax toxin to its receptor is similar to alpha integrin-ligand interactionsStructure of heptameric protective antigen bound to an anthrax toxin receptor: a role for receptor in pH-dependent pore formationEvidence against a human cell-specific role for LRP6 in anthrax toxin entryBinding stoichiometry and kinetics of the interaction of a human anthrax toxin receptor, CMG2, with protective antigenSusceptibility of mitogen-activated protein kinase kinase family members to proteolysis by anthrax lethal factorMetalloproteinase inhibitors, nonantimicrobial chemically modified tetracyclines, and ilomastat block Bacillus anthracis lethal factor activity in viable cellsA model of anthrax toxin lethal factor bound to protective antigen.Binary bacterial toxins: biochemistry, biology, and applications of common Clostridium and Bacillus proteinsCrystal structure of the von Willebrand factor A domain of human capillary morphogenesis protein 2: an anthrax toxin receptorAnthrax toxin triggers endocytosis of its receptor via a lipid raft-mediated clathrin-dependent processHuman anti-anthrax protective antigen neutralizing monoclonal antibodies derived from donors vaccinated with anthrax vaccine adsorbedTumor Targeting and Drug Delivery by Anthrax ToxinAnthrax Toxins in Context of Bacillus anthracis Spores and Spore GerminationObstructing toxin pathways by targeted pore blockageAnthrax lethal and edema toxins in anthrax pathogenesisBacillus anthracis edema factor substrate specificity: evidence for new modes of actionCytoskeleton as an emerging target of anthrax toxinsLRP5 and LRP6 are not required for protective antigen-mediated internalization or lethality of anthrax lethal toxinCrystal structure of the anthrax lethal factorThe structural basis for substrate and inhibitor selectivity of the anthrax lethal factorIdentification of small molecule inhibitors of anthrax lethal factorCrystal Structure of Bacillus anthracis Transpeptidase Enzyme CapDCerthrax Toxin, an Anthrax-related ADP-ribosyltransferase from Bacillus cereusCathepsin B-mediated autophagy flux facilitates the anthrax toxin receptor 2-mediated delivery of anthrax lethal factor into the cytoplasmA conserved docking site in MEKs mediates high-affinity binding to MAP kinases and cooperates with a scaffold protein to enhance signal transmissionAdvax-adjuvanted recombinant protective antigen provides protection against inhalational anthrax that is further enhanced by addition of murabutide adjuvantProtective antigen as a correlative marker for anthrax in animal modelsA viral nanoparticle with dual function as an anthrax antitoxin and vaccineTailored ß-cyclodextrin blocks the translocation pores of binary exotoxins from C. botulinum and C. perfringens and protects cells from intoxicationNLRP1-dependent pyroptosis leads to acute lung injury and morbidity in miceCapillary morphogenesis protein-2 is the major receptor mediating lethality of anthrax toxin in vivo.Anthrax lethal factor cleaves MKK3 in macrophages and inhibits the LPS/IFNgamma-induced release of NO and TNFalphaIon selectivity of the anthrax toxin channel and its effect on protein translocation.Membrane insertion by anthrax protective antigen in cultured cells.Point mutations in anthrax protective antigen that block translocation.Nod1/Nod2-mediated recognition plays a critical role in induction of adaptive immunity to anthrax after aerosol exposure.Circulating lethal toxin decreases the ability of neutrophils to respond to Bacillus anthracis.Disruption of anthrax toxin binding with the use of human antibodies and competitive inhibitors.Anthrax lethal toxin induced lysosomal membrane permeabilization and cytosolic cathepsin release is Nlrp1b/Nalp1b-dependent.
P2860
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P2860
Anthrax lethal factor cleaves the N-terminus of MAPKKs and induces tyrosine/threonine phosphorylation of MAPKs in cultured macrophages.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
1998年论文
@zh
1998年论文
@zh-cn
name
Anthrax lethal factor cleaves ...... MAPKs in cultured macrophages.
@en
type
label
Anthrax lethal factor cleaves ...... MAPKs in cultured macrophages.
@en
prefLabel
Anthrax lethal factor cleaves ...... MAPKs in cultured macrophages.
@en
P2093
P356
P1476
Anthrax lethal factor cleaves ...... MAPKs in cultured macrophages.
@en
P2093
C Montecucco
G Napolitani
R Pellizzari
P304
P356
10.1006/BBRC.1998.9040
P577
1998-07-01T00:00:00Z