Selective inhibition of phosphodiesterases 4, 5 and 9 induces HSP20 phosphorylation and attenuates amyloid beta 1-42-mediated cytotoxicity

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Cyclic nucleotide signaling changes associated with normal aging and age-related diseases of the brain.

P2860

Q45305673-33E8579E-4D06-4771-A2FA-1E6EF80E07D0

P2860

Selective inhibition of phosphodiesterases 4, 5 and 9 induces HSP20 phosphorylation and attenuates amyloid beta 1-42-mediated cytotoxicity

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http://www.wikidata.org/entity/Q41016698

description

2016 nî lūn-bûn

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2016年の論文

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2016年論文

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2016年論文

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2016年論文

@zh-hk

2016年論文

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2016年論文

@zh-tw

2016年论文

@wuu

2016年论文

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2016年论文

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name

Selective inhibition of phosph ...... eta 1-42-mediated cytotoxicity

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type

Item

label

Selective inhibition of phosph ...... eta 1-42-mediated cytotoxicity

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prefLabel

Selective inhibition of phosph ...... eta 1-42-mediated cytotoxicity

@en

P1476

Selective inhibition of phosph ...... eta 1-42-mediated cytotoxicity

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P2093

Anna I Parachikova

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Ellanor Whiteley

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Jon P Day

http://www.w3.org/2001/XMLSchema#string

Ryan T Cameron

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P2860

Quantitative colocalization analysis of multicolor confocal immunofluorescence microscopy images: pushing pixels to explore biological phenomena

The amyloid hypothesis of Alzheimer's disease at 25 years

Global and local missions of cAMP signaling in neural plasticity, learning, and memory

Phosphodiesterases as therapeutic targets for Alzheimer's disease.

Diffusible, nonfibrillar ligands derived from Abeta1-42 are potent central nervous system neurotoxins

Amyloid seeds formed by cellular uptake, concentration, and aggregation of the amyloid-beta peptide.

Advances in targeting cyclic nucleotide phosphodiesterases

Design and discovery of 6-[(3S,4S)-4-methyl-1-(pyrimidin-2-ylmethyl)pyrrolidin-3-yl]-1-(tetrahydro-2H-pyran-4-yl)-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one (PF-04447943), a selective brain penetrant PDE9A inhibitor for the treatment of cognitive

Small heat shock protein 20 (HspB6) in cardiac hypertrophy and failure

The A-kinase-anchoring protein AKAP-Lbc facilitates cardioprotective PKA phosphorylation of Hsp20 on Ser(16).

P304

64-73

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scholarly article

P356

10.1002/2211-5463.12156

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P433

http://www.w3.org/2001/XMLSchema#string

P478

http://www.w3.org/2001/XMLSchema#string

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George Baillie

P577

2016-12-05T00:00:00Z

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P698

28097089

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P932

5221464

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Selective inhibition of phosphodiesterases 4, 5 and 9 induces HSP20 phosphorylation and attenuates amyloid beta 1-42-mediated cytotoxicity

about

P2860

P2860

Selective inhibition of phosphodiesterases 4, 5 and 9 induces HSP20 phosphorylation and attenuates amyloid beta 1-42-mediated cytotoxicity

description

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type

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P1476

P2093

P2860

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P698

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P1476

P2093

P2860

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P31

P356

P433

P478

P50

P577

P698

P932