Elastase regulates the synthesis of its inhibitor, alpha 1-proteinase inhibitor, and exaggerates the defect in homozygous PiZZ alpha 1 PI deficiency.

Elastase regulates the synthesis of its inhibitor, alpha 1-proteinase inhibitor, and exaggerates the defect in homozygous PiZZ alpha 1 PI deficiency.

Item
http://www.wikidata.org/entity/Q41017471
Constitutive and inducible expression of SKALP/elafin provides anti-elastase defense in human epitheliaIdentification of a serpin-enzyme complex receptor on human hepatoma cells and human monocytes.A common neoepitope is created when the reactive center of C1-inhibitor is cleaved by plasma kallikrein, activated factor XII fragment, C1 esterase, or neutrophil elastase.Interferon beta 2/interleukin 6 modulates synthesis of alpha 1-antitrypsin in human mononuclear phagocytes and in human hepatoma cells.Synthesis of stress proteins is increased in individuals with homozygous PiZZ alpha 1-antitrypsin deficiency and liver diseaseIn vivo patterns of expression of urokinase and its inhibitor PAI-1 suggest a concerted role in regulating physiological angiogenesis.Alpha-1 antitrypsin: a potent anti-inflammatory and potential novel therapeutic agent.The serpin-enzyme complex (SEC) receptor mediates the neutrophil chemotactic effect of alpha-1 antitrypsin-elastase complexes and amyloid-beta peptide.Alpha-1-antitrypsin stimulates fibroblast proliferation and procollagen production and activates classical MAP kinase signalling pathways.Structure of the azurocidin, proteinase 3, and neutrophil elastase genes. Implications for inflammation and vasculitis.Role of the proposed serpin-enzyme complex receptor recognition site in binding and internalization of thrombin-heparin cofactor II complexes by hepatocytes.Protease inhibitors and carcinogenesis: a review.Differential recognition of alpha 1-antitrypsin-elastase and alpha 1-antichymotrypsin-cathepsin G complexes by the low density lipoprotein receptor-related protein.C1 inhibitor-C1s complexes are internalized and degraded by the low density lipoprotein receptor-related protein.Analysis of a structural determinant in thrombin-protease nexin 1 complexes that mediates clearance by the low density lipoprotein receptor-related protein.The efficient catabolism of thrombin-protease nexin 1 complexes is a synergistic mechanism that requires both the LDL receptor-related protein and cell surface heparins.Well-Known and Less Well-Known Functions of Alpha-1 Antitrypsin. Its Role in Chronic Obstructive Pulmonary Disease and Other Disease Developments.
P2860

Elastase regulates the synthesis of its inhibitor, alpha 1-proteinase inhibitor, and exaggerates the defect in homozygous PiZZ alpha 1 PI deficiency.

Item
http://www.wikidata.org/entity/Q41017471
description
1988 nî lūn-bûn
@nan
1988年の論文
@ja
1988年論文
@yue
1988年論文
@zh-hant
1988年論文
@zh-hk
1988年論文
@zh-mo
1988年論文
@zh-tw
1988年论文
@wuu
1988年论文
@zh
1988年论文
@zh-cn
name
Elastase regulates the synthes ...... us PiZZ alpha 1 PI deficiency.
@en
type
label
Elastase regulates the synthes ...... us PiZZ alpha 1 PI deficiency.
@en
prefLabel
Elastase regulates the synthes ...... us PiZZ alpha 1 PI deficiency.
@en
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P698
P932
P356
P1433
P1476
Elastase regulates the synthes ...... us PiZZ alpha 1 PI deficiency.
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P698
P932