Differential etoposide sensitivity of cells deficient in the Ku and DNA-PKcs components of the DNA-dependent protein kinase.
about
Targeting DNA topoisomerase II in cancer chemotherapyEffects of camptothecin on double-strand break repair by non-homologous end-joining in DNA mismatch repair-deficient human colorectal cancer cell linesCharacterisation of cytotoxicity and DNA damage induced by the topoisomerase II-directed bisdioxopiperazine anti-cancer agent ICRF-187 (dexrazoxane) in yeast and mammalian cellsTerminal DNA structure and ATP influence binding parameters of the DNA-dependent protein kinase at an early step prior to DNA synapsis.Collision of Trapped Topoisomerase 2 with Transcription and Replication: Generation and Repair of DNA Double-Strand Breaks with 5' AdductsNumerical analysis of etoposide induced DNA breaksInhibition of homologous recombination by variants of the catalytic subunit of the DNA-dependent protein kinase (DNA-PKcs)Radiosensitive severe combined immunodeficiency disease.RAD51 supports spontaneous non-homologous recombination in mammalian cells, but not the corresponding process induced by topoisomerase inhibitorsDNA topoisomerase II as a target for cancer chemotherapy.Smad4 loss promotes lung cancer formation but increases sensitivity to DNA topoisomerase inhibitors.Proteasomal inhibition potentiates drugs targeting DNA topoisomerase II.Unstabilized DNA breaks in HTLV-1 Tax expressing cells correlate with functional targeting of Ku80, not PKcs, XRCC4, or H2AX.Hypersensitivity of nonhomologous DNA end-joining mutants to VP-16 and ICRF-193: implications for the repair of topoisomerase II-mediated DNA damage.Increased and correlated nuclear factor-kappa B and Ku autoantigen activities are associated with development of multidrug resistance.Distinct pathways of nonhomologous end joining that are differentially regulated by DNA-dependent protein kinase-mediated phosphorylation.Impaired DNA double-strand break repair contributes to chemoresistance in HIF-1 alpha-deficient mouse embryonic fibroblasts.Nuclear α-catenin mediates the DNA damage response via β-catenin and nuclear actin.Progression of chromosomal damage induced by etoposide in G2 phase in a DNA-PKcs-deficient context.
P2860
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P2860
Differential etoposide sensitivity of cells deficient in the Ku and DNA-PKcs components of the DNA-dependent protein kinase.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
1998年论文
@zh
1998年论文
@zh-cn
name
Differential etoposide sensiti ...... DNA-dependent protein kinase.
@en
type
label
Differential etoposide sensiti ...... DNA-dependent protein kinase.
@en
prefLabel
Differential etoposide sensiti ...... DNA-dependent protein kinase.
@en
P2093
P356
P1433
P1476
Differential etoposide sensiti ...... DNA-dependent protein kinase.
@en
P2093
P304
P356
10.1093/CARCIN/19.6.965
P407
P577
1998-06-01T00:00:00Z