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Bisphosphonates target multiple sites in both cis- and trans-prenyltransferasesStructure-Based Inhibitors Exhibit Differential Activities againstHelicobacter pyloriandEscherichia coliUndecaprenyl Pyrophosphate SynthasesInhibition of Geranylgeranyl Diphosphate Synthase by Bisphosphonates: A Crystallographic and Computational Investigation †Lipophilic Bisphosphonates as Dual Farnesyl/Geranylgeranyl Diphosphate Synthase Inhibitors: An X-ray and NMR InvestigationStructure of the alkalohyperthermophilic Archaeoglobus fulgidus lipase contains a unique C-terminal domain essential for long-chain substrate bindingCrystal structure and substrate-binding mode of cellulase 12A from Thermotoga maritimaCrystal structures of Bacillus alkaline phytase in complex with divalent metal ions and inositol hexasulfateDiverse substrate recognition mechanism revealed by Thermotoga maritima Cel5A structures in complex with cellotetraose, cellobiose and mannotrioseThe substrate/product-binding modes of a novel GH120 β-xylosidase (XylC) from Thermoanaerobacterium saccharolyticum JW/SL-YS485Substrate binding of a GH5 endoglucanase from the ruminal fungusPiromyces rhizinflataInsights into TIM-Barrel Prenyl Transferase Mechanisms: Crystal Structures of PcrB fromBacillus subtilisandStaphylococcus aureusEnhanced activity of Thermotoga maritima cellulase 12A by mutating a unique surface loopCrystal structure and substrate-binding mode of a novel pectate lyase from alkaliphilic Bacillus sp. N16-5Crystal structures of d-psicose 3-epimerase from Clostridium cellulolyticum H10 and its complex with ketohexose sugarsInsights into the Mechanism of the Antibiotic-Synthesizing Enzyme MoeO5 from Crystal Structures of Different ComplexesStructure and Inhibition of Tuberculosinol Synthase and Decaprenyl Diphosphate Synthase from Mycobacterium tuberculosisSqualene synthase as a target for Chagas disease therapeuticsCrystal structures of ligand-bound octaprenyl pyrophosphate synthase fromEscherichia colireveal the catalytic and chain-length determining mechanismsStructural and functional analyses of catalytic domain of GH10 xylanase from Thermoanaerobacterium saccharolyticum JW/SL-YS485Structural and mutagenetic analyses of a 1,3-1,4-β-glucanase from Paecilomyces thermophilaStructural and mutational studies on the unusual substrate specificity of meso-diaminopimelate dehydrogenase from Symbiobacterium thermophilumUnconserved substrate-binding sites direct the stereoselectivity of medium-chain alcohol dehydrogenaseRoles of tryptophan residue and disulfide bond in the variable lid region of oxidized polyvinyl alcohol hydrolaseStructural perspectives of an engineered β-1,4-xylanase with enhanced thermostabilityBinding mode of the oxidized α-anomer of NAD+ to RSP, a Rex-family repressorStructural analyses and yeast production of the β-1,3-1,4-glucanase catalytic module encoded by the licB gene of Clostridium thermocellumCrystal structures of S-adenosylhomocysteine hydrolase from the thermophilic bacterium Thermotoga maritimaStructural insight into potential cold adaptation mechanism through a psychrophilic glycoside hydrolase family 10 endo-β-1,4-xylanaseFunctional and structural analyses of a 1,4-β-endoglucanase from Ganoderma lucidumCharacterization and crystal structure of a thermostable glycoside hydrolase family 45 1,4-β-endoglucanase from Thielavia terrestris.Moenomycin Biosynthesis: Structure and Mechanism of Action of the Prenyltransferase MoeN5.Crystal structure and genetic modifications of FI-CMCase from Aspergillus aculeatus F-50.SQ109, a new drug lead for Chagas disease.Structures of Iridoid Synthase from Cantharanthus roseus with Bound NAD(+) , NADPH, or NAD(+) /10-Oxogeranial: Reaction Mechanisms.Crystallization and preliminary X-ray diffraction analysis of a novel β-L-arabinofuranosidase (HypBA1) from Bifidobacterium longum.Structural analysis of a glycoside hydrolase family 11 xylanase from Neocallimastix patriciarum: insights into the molecular basis of a thermophilic enzyme.Crystallization and preliminary X-ray diffraction analysis of (R)-carbonyl reductase from Candida parapsilosisMultitarget drug discovery for tuberculosis and other infectious diseases.Structure, function and inhibition of ent-kaurene synthase from Bradyrhizobium japonicumStructural and functional analysis of Bacillus subtilis YisP reveals a role of its product in biofilm production.
P50
Q27645000-CA40C46B-036A-4061-B71C-5381CE2E7B02Q27650204-33BE5E1E-5145-4359-B6AF-65B7CCD62DD2Q27652214-37A97598-32C8-4AC3-85A6-B6AD78B36830Q27654261-21F24DE6-CC8E-4FD6-97A4-335F124A941DQ27655496-24C000E1-CDF1-4B1B-B41C-98A83F1748E0Q27666584-098594EF-FB3D-4ED8-9F64-E1A927854063Q27667159-31B4C0D1-7DE6-44A4-A2C6-B66A45CEB7E8Q27671713-364AA21C-4E7A-4ADD-82E8-1C81904A4F11Q27673410-30B921B9-CB75-48A5-AEE6-022157769A4EQ27675694-C81A5251-2F4A-4439-AF6F-742CBEDF96EEQ27675912-05775B28-C20F-40B4-92A6-018C1B5117B3Q27676211-5EF83CFB-5B52-4FBC-9E3F-CB63A52558ABQ27678034-13975C31-E690-4DAA-912B-93B80EB872C8Q27678081-22703007-5F38-447A-8489-F03C51C4BA28Q27678093-103CDB10-5697-493F-9480-22D497A741ACQ27681516-7FF28AEB-1B7A-4078-A3CE-8F6215BDF556Q27683611-CDC7A400-674E-43DD-A399-765F925D94FFQ27684067-5FF872AC-7A27-49B9-B0C0-717DD60F2F32Q27684204-02A5CC01-2BD8-40B3-963F-250F8D86E8FFQ27687635-5D52F220-91EC-48BB-920B-89D5B86A5A94Q27687981-F90891D7-9BA5-4600-8945-E335EE05B7B0Q27690247-35B81ACF-4587-4887-B7F2-3C294A09307BQ27694828-965033C3-C2ED-4968-B617-989338145240Q27695571-362B9E99-FD12-4C14-8DDE-DB0CB619C29FQ27696883-1CC42488-2ED3-496B-8C80-684702BFFC1EQ27698478-A9C8B838-A1B8-4FE0-8450-9FEF5D1219A3Q27698549-E02D4026-6A85-4C5C-ACC6-6FC9140308F2Q27703279-C645A30C-2568-47E5-8405-7EFA06265F18Q27704274-026F0BE7-9ED4-497D-9AE9-BEF4D7CE43F4Q30152664-DC203DF1-CCA5-4A6E-8D1D-8555E07FDC7CQ30385391-343390A0-E6D4-401B-AE19-B4FD465462CAQ30391143-A5C71609-F74E-44D1-98FA-560374C107FCQ30626912-2BDC7BBD-0B6A-48EA-A0F8-3ED61FCF8915Q30699611-F8D4881D-DD91-4CFD-AA07-CE44241BBE65Q33583379-156E8377-322A-466E-AFA7-2303EB6334B0Q33676185-AFBEA710-4776-455B-9260-81D9F20BB97EQ33733719-DCE576D6-F724-449A-ADDA-985CD24C318BQ33854785-24ABD280-4A80-49FC-9B41-6FE99F2EB1B3Q34270586-441FD906-E7E3-42E4-BE25-61DF9A2C3F29Q34615108-8D7C0E63-21D7-491F-9490-2FEA7C011B73
P50
description
onderzoeker
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researcher
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հետազոտող
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name
Rey-Ting Guo
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Rey-Ting Guo
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Rey-Ting Guo
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Rey-Ting Guo
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Rey-Ting Guo
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Rey-Ting Guo
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Rey-Ting Guo
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Rey-Ting Guo
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Rey-Ting Guo
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P106
P31
P496
0000-0003-2942-7246