about
Rites of passage: requirements and standards for building kinetic models of metabolic phenotypesDesign of computational retrobiosynthesis tools for the design of de novo synthetic pathwaysA novel pulse-chase SILAC strategy measures changes in protein decay and synthesis rates induced by perturbation of proteostasis with an Hsp90 inhibitorMetabolic Needs and Capabilities of Toxoplasma gondii through Combined Computational and Experimental AnalysisManipulating redox and ATP balancing for improved production of succinate in E. coliA genome-scale metabolic reconstruction for Escherichia coli K-12 MG1655 that accounts for 1260 ORFs and thermodynamic informationMetabolic networks: enzyme function and metabolite structure.A genome-scale integration and analysis of Lactococcus lactis translation data.A computational framework for integration of lipidomics data into metabolic pathways.A method for analysis and design of metabolism using metabolomics data and kinetic models: Application on lipidomics using a novel kinetic model of sphingolipid metabolism.A model-based optimization framework for the inference on gene regulatory networks from DNA array data.Exploring the diversity of complex metabolic networks.In silico feasibility of novel biodegradation pathways for 1,2,4-trichlorobenzene.The origins of time-delay in template biopolymerization processes.Mathematical modeling of the eukaryotic heat-shock response: dynamics of the hsp70 promoter.An algorithmic framework for genome-wide modeling and analysis of translation networksJay Bailey as mentor--the students' perspective.A memorial review of Jay Bailey's contribution in prokaryotic metabolic engineering.A model for protein translation: polysome self-organization leads to maximum protein synthesis rates.Model-Driven Understanding of Palmitoylation Dynamics: Regulated Acylation of the Endoplasmic Reticulum Chaperone CalnexinBioenergetics-based modeling of Plasmodium falciparum metabolism reveals its essential genes, nutritional requirements, and thermodynamic bottlenecks.Effects of codon distributions and tRNA competition on protein translationMechanistically consistent reduced models of synthetic gene networks.Quantification of Cooperativity in Heterodimer-DNA Binding Improves the Accuracy of Binding Specificity Models.Analysis of Translation Elongation Dynamics in the Context of an Escherichia coli CellFunctional genomics of Plasmodium falciparum using metabolic modelling and analysisKinetic models in industrial biotechnology - Improving cell factory performance.Identification and dynamics of the human ZDHHC16-ZDHHC6 palmitoylation cascade.redGEM: Systematic reduction and analysis of genome-scale metabolic reconstructions for development of consistent core metabolic models.A design-build-test cycle using modeling and experiments reveals interdependencies between upper glycolysis and xylose uptake in recombinant S. cerevisiae and improves predictive capabilities of large-scale kinetic modelsIdentification of metabolic engineering targets for the enhancement of 1,4-butanediol production in recombinant E. coli using large-scale kinetic models.Mechanistic Modeling of Genetic Circuits for ArsR Arsenic Regulation.Thermodynamics-based Metabolite Sensitivity Analysis in metabolic networks.Theoretical considerations and computational analysis of the complexity in polyketide synthesis pathways.iSCHRUNK--In Silico Approach to Characterization and Reduction of Uncertainty in the Kinetic Models of Genome-scale Metabolic Networks.lumpGEM: Systematic generation of subnetworks and elementally balanced lumped reactions for the biosynthesis of target metabolites.Thermodynamics-based metabolic flux analysisTunable reporter signal production in feedback-uncoupled arsenic bioreporters.Bistability explains threshold phenomena in protein aggregation both in vitro and in vivo.Genome-scale thermodynamic analysis of Escherichia coli metabolism
P50
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P50
description
hulumtues
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onderzoeker
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researcher
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հետազոտող
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name
Vassily Hatzimanikatis
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Vassily Hatzimanikatis
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Vassily Hatzimanikatis
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Vassily Hatzimanikatis
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type
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Vassily Hatzimanikatis
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Vassily Hatzimanikatis
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Vassily Hatzimanikatis
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Vassily Hatzimanikatis
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Vassily Hatzimanikatis
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Vassily Hatzimanikatis
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Vassily Hatzimanikatis
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Vassily Hatzimanikatis
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P1053
G-6505-2010
P106
P1960
GfcsivYAAAAJ
P2038
Vassily_Hatzimanikatis
P21
P2381
P2456
P2798
P31
P3829
P4012
P496
0000-0001-6432-4694