A mutation in the aryl hydrocarbon receptor (AHR) in a cultured mammalian cell line identifies a novel region of AHR that affects DNA binding.
about
Interaction networks in yeast define and enumerate the signaling steps of the vertebrate aryl hydrocarbon receptorHuman variants in the neuronal basic helix-loop-helix/Per-Arnt-Sim (bHLH/PAS) transcription factor complex NPAS4/ARNT2 disrupt functionIdentification and functional characterization of two highly divergent aryl hydrocarbon receptors (AHR1 and AHR2) in the teleost Fundulus heteroclitus. Evidence for a novel subfamily of ligand-binding basic helix loop helix-Per-ARNT-Sim (bHLH-PAS) fSU5416, a VEGF receptor inhibitor and ligand of the AHR, represents a new alternative for immunomodulationThe Ah receptor recruits IKKα to its target binding motifs to phosphorylate serine-10 in histone H3 required for transcriptional activation.Endogenous aryl hydrocarbon receptor promotes basal and inducible expression of tumor necrosis factor target genes in MCF-7 cancer cellsIdentification of residues in the N-terminal PAS domains important for dimerization of Arnt and AhR.Genomewide analysis of aryl hydrocarbon receptor binding targets reveals an extensive array of gene clusters that control morphogenetic and developmental programs.Genetic variation at aryl hydrocarbon receptor (AHR) loci in populations of Atlantic killifish (Fundulus heteroclitus) inhabiting polluted and reference habitats.Hypoxia-inducible mammalian gene expression analyzed in vivo at a TATA-driven promoter and at an initiator-driven promoter.Structural modeling of the AhR:ARNT complex in the bHLH-PASA-PASB region elucidates the key determinants of dimerization.The aryl hydrocarbon receptor displaces p300 from E2F-dependent promoters and represses S phase-specific gene expression.Role of mediator in transcriptional activation by the aryl hydrocarbon receptor.Differential usage of nuclear export sequences regulates intracellular localization of the dioxin (aryl hydrocarbon) receptor.Induction and regulation of the carcinogen-metabolizing enzyme CYP1A1 by marijuana smoke and delta (9)-tetrahydrocannabinol.Role of the Per/Arnt/Sim domains in ligand-dependent transformation of the aryl hydrocarbon receptor.Characterization of the aryl hydrocarbon receptor repressor gene and association of its Pro185Ala polymorphism with micropenis.Identification of a critical amino acid in the aryl hydrocarbon receptor.Contribution of the Per/Arnt/Sim (PAS) domains to DNA binding by the basic helix-loop-helix PAS transcriptional regulators.Novel DNA binding by a basic helix-loop-helix protein. The role of the dioxin receptor PAS domain.Phenethyl isothiocyanate, a naturally occurring phytochemical, is an antagonist of the aryl hydrocarbon receptor
P2860
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P2860
A mutation in the aryl hydrocarbon receptor (AHR) in a cultured mammalian cell line identifies a novel region of AHR that affects DNA binding.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年学术文章
@wuu
1997年学术文章
@zh-cn
1997年学术文章
@zh-hans
1997年学术文章
@zh-my
1997年学术文章
@zh-sg
1997年學術文章
@yue
1997年學術文章
@zh
1997年學術文章
@zh-hant
name
A mutation in the aryl hydroca ...... AHR that affects DNA binding.
@en
type
label
A mutation in the aryl hydroca ...... AHR that affects DNA binding.
@en
prefLabel
A mutation in the aryl hydroca ...... AHR that affects DNA binding.
@en
P2093
P2860
P356
P1476
A mutation in the aryl hydroca ...... AHR that affects DNA binding.
@en
P2093
P2860
P304
31845-31854
P356
10.1074/JBC.272.50.31845
P407
P577
1997-12-01T00:00:00Z