Optimal matrix rigidity for stress fiber polarization in stem cells.
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Mechanotransduction and extracellular matrix homeostasisCyclic tensile strain controls cell shape and directs actin stress fiber formation and focal adhesion alignment in spreading cellsRole of Mechanical Cues in Cell Differentiation and Proliferation: A 3D Numerical ModelPhysically-induced cytoskeleton remodeling of cells in three-dimensional cultureNuclear deformability and telomere dynamics are regulated by cell geometric constraints.The direction of stretch-induced cell and stress fiber orientation depends on collagen matrix stressSubstrate engagement of integrins α5β1 and αvβ3 is necessary, but not sufficient, for high directional persistence in migration on fibronectinDisordered actomyosin networks are sufficient to produce cooperative and telescopic contractilityFrom molecular signal activation to locomotion: an integrated, multiscale analysis of cell motility on defined matricesMathematical modeling of eukaryotic cell migration: insights beyond experimentsStem cell mechanobiology: diverse lessons from bone marrowA biomechanical perspective on stress fiber structure and functionEmergent complexity of the cytoskeleton: from single filaments to tissueCell visco-elasticity measured with AFM and optical trapping at sub-micrometer deformationsThe filament sensor for near real-time detection of cytoskeletal fiber structuresA Robust Actin Filaments Image Analysis FrameworkNano- and microstructured materials for in vitro studies of the physiology of vascular cellsMesenchymal stem cell adhesion but not plasticity is affected by high substrate stiffnessFrequent mechanical stress suppresses proliferation of mesenchymal stem cells from human bone marrow without loss of multipotencyDynamic and structural signatures of lamellar actomyosin force generationEvidence of a large-scale mechanosensing mechanism for cellular adaptation to substrate stiffness.Crawling from soft to stiff matrix polarizes the cytoskeleton and phosphoregulates myosin-II heavy chain.Stiffness-modulated water retention and neovascularization of dermal fibroblast-encapsulating collagen gelForce fluctuations in three-dimensional suspended fibroblasts.Physics of cell adhesion: some lessons from cell-mimetic systems.Front-Rear Polarization by Mechanical Cues: From Single Cells to Tissues.Matrix elasticity regulates the optimal cardiac myocyte shape for contractility.Matrix Mechanosensing: From Scaling Concepts in 'Omics Data to Mechanisms in the Nucleus, Regeneration, and Cancer.Stiffness gradients mimicking in vivo tissue variation regulate mesenchymal stem cell fate.Cyclic stress at mHz frequencies aligns fibroblasts in direction of zero strain.GEF-H1 controls focal adhesion signaling that regulates mesenchymal stem cell lineage commitment.Dynamic mechanisms of cell rigidity sensing: insights from a computational model of actomyosin networks.Spatiotemporally controlled microchannels of periodontal mimic scaffolds.Long-range force transmission in fibrous matrices enabled by tension-driven alignment of fibersEvaluation of physical and mechanical properties of porous poly (ethylene glycol)-co-(L-lactic acid) hydrogels during degradation.Measurement and analysis of traction force dynamics in response to vasoactive agonistsStriated acto-myosin fibers can reorganize and register in response to elastic interactions with the matrix.Role of mechanical factors in fate decisions of stem cells.Cells as liquid motors: mechanosensitivity emerges from collective dynamics of actomyosin cortex.A novel cell traction force microscopy to study multi-cellular system
P2860
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P2860
Optimal matrix rigidity for stress fiber polarization in stem cells.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
Optimal matrix rigidity for stress fiber polarization in stem cells.
@en
type
label
Optimal matrix rigidity for stress fiber polarization in stem cells.
@en
prefLabel
Optimal matrix rigidity for stress fiber polarization in stem cells.
@en
P2860
P50
P356
P1433
P1476
Optimal matrix rigidity for stress fiber polarization in stem cells
@en
P2093
P2860
P2888
P304
P356
10.1038/NPHYS1613
P577
2010-06-01T00:00:00Z