Progression through mitosis promotes PARP inhibitor-induced cytotoxicity in homologous recombination-deficient cancer cells.

about

BRCA1 gene: function and deficiency.Never tear us a-PARP: Dealing with DNA lesions during mitosis.Augmented antitumor activity by olaparib plus AZD1775 in gastric cancer through disrupting DNA damage repair pathways and DNA damage checkpoint.

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P2860

Progression through mitosis promotes PARP inhibitor-induced cytotoxicity in homologous recombination-deficient cancer cells.

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http://www.wikidata.org/entity/Q41077638

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2017 nî lūn-bûn

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2017年の論文

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2017年学术文章

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2017年学术文章

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2017年学术文章

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2017年学术文章

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2017年学术文章

@zh-sg

2017年學術文章

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2017年學術文章

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2017年學術文章

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name

Progression through mitosis pr ...... nation-deficient cancer cells.

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type

Item

label

Progression through mitosis pr ...... nation-deficient cancer cells.

@en

prefLabel

Progression through mitosis pr ...... nation-deficient cancer cells.

@en

P1476

Progression through mitosis pr ...... nation-deficient cancer cells.

@en

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Ewa Gogola

http://www.w3.org/2001/XMLSchema#string

Francien Talens

http://www.w3.org/2001/XMLSchema#string

Jos Jonkers

http://www.w3.org/2001/XMLSchema#string

Madalena Tarsounas

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Marcel A T M van Vugt

http://www.w3.org/2001/XMLSchema#string

Pepijn M Schoonen

http://www.w3.org/2001/XMLSchema#string

Peter Bouwman

http://www.w3.org/2001/XMLSchema#string

Sohvi Blatter

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P2860

Differential expression analysis for sequence count data

High sensitivity of BRCA1-deficient mammary tumors to the PARP inhibitor AZD2281 alone and in combination with platinum drugs

Interplay between Fanconi anemia and homologous recombination pathways in genome integrity

Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy

A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1

Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase

Emi1 is a mitotic regulator that interacts with Cdc20 and inhibits the anaphase promoting complex

Efficacy of neoadjuvant Cisplatin in triple-negative breast cancer

A mitotic phosphorylation feedback network connects Cdk1, Plk1, 53BP1, and Chk2 to inactivate the G(2)/M DNA damage checkpoint

Mouse emi1 has an essential function in mitotic progression during early embryogenesis

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ncomms15981

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15981

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scholarly article

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10.1038/NCOMMS15981

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English

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http://www.w3.org/2001/XMLSchema#string

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Floris Foijer

Sven Rottenberg

Anne Margriet Heijink

Colin Stok

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2017-07-17T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

28714471

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P921

cytotoxicity

P932

5520019

http://www.w3.org/2001/XMLSchema#string

Progression through mitosis promotes PARP inhibitor-induced cytotoxicity in homologous recombination-deficient cancer cells.

about

P2860

P2860

Progression through mitosis promotes PARP inhibitor-induced cytotoxicity in homologous recombination-deficient cancer cells.

description

name

type

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P1433

P1476

P2093

P2860

P2888

P304

P31

P356

P407

P478

P50

P577

P698

P921

P932

P356

P1433

P1476

P2093

P2860

P2888

P304

P31

P356

P407

P478

P50

P577

P698

P921

P932