Direct stimulation of Bruton's tyrosine kinase by G(q)-protein alpha-subunit. - Wikidata - awgldk - TriplyDB

Direct stimulation of Bruton's tyrosine kinase by G(q)-protein alpha-subunit.

Direct stimulation of Bruton's tyrosine kinase by G(q)-protein alpha-subunit.

http://www.wikidata.org/entity/Q41090124

about

Bruton's tyrosine kinase activity is negatively regulated by Sab, the Btk-SH3 domain-binding protein PHR1 encodes an abundant, pleckstrin homology domain-containing integral membrane protein in the photoreceptor outer segments Etk, a Btk family tyrosine kinase, mediates cellular transformation by linking Src to STAT3 activation.Direct inhibition of Bruton's tyrosine kinase by IBtk, a Btk-binding protein Identification of the binding site for Gqalpha on its effector Bruton's tyrosine kinase Expansion of signal transduction by G proteins. The second 15 years or so: from 3 to 16 alpha subunits plus betagamma dimers Neuropeptide-induced androgen independence in prostate cancer cells: roles of nonreceptor tyrosine kinases Etk/Bmx, Src, and focal adhesion kinase Protein-tyrosine phosphatase D1, a potential regulator and effector for Tec family kinases The Bmx tyrosine kinase is activated by IL-3 and G-CSF in a PI-3K dependent manner Identification of phosphorylation sites for Bruton's tyrosine kinase within the transcriptional regulator BAP/TFII-I G Protein beta gamma subunits act on the catalytic domain to stimulate Bruton's agammaglobulinemia tyrosine kinase Proteolytic activation of ETK/Bmx tyrosine kinase by caspases The proline rich region of the Tec homology domain of ITK regulates its activity Competing modes of self-association in the regulatory domains of Bruton's tyrosine kinase: intramolecular contact versus asymmetric homodimerization Purification of an EH domain-binding protein from rat brain that modulates the gating of the rat ether-à-go-go channel Identification and characterization of a molecule, BAM11, that associates with the pleckstrin homology domain of mouse Btk Autoinhibition of Bruton's tyrosine kinase (Btk) and activation by soluble inositol hexakisphosphate.The Tec family kinase Itk exists as a folded monomer in vivo.In situ detection of activated Bruton's tyrosine kinase in the Ig signaling complex by phosphopeptide-specific monoclonal antibodies.Functional analysis of the T-cell-restricted protein tyrosine kinase Txk.Inhibition of a background potassium channel by Gq protein alpha-subunits.The G protein beta5 subunit interacts selectively with the Gq alpha subunit.RGS4 is required for dopaminergic control of striatal LTD and susceptibility to parkinsonian motor deficits Activation state-dependent interaction between Gαq subunits and the Fhit tumor suppressor.A bead-based activity screen for small-molecule inhibitors of signal transduction in chronic myelogenous leukemia cells.A phosphorylation site in Bruton's tyrosine kinase selectively regulates B cell calcium signaling efficiency by altering phospholipase C-gamma activation.Interplay between the heterotrimeric G-protein subunits Galphaq and Galphai2 sets the threshold for chemotaxis and TCR activation.Severe B cell deficiency and disrupted splenic architecture in transgenic mice expressing the E41K mutated form of Bruton's tyrosine kinase.Tec/Bmx non-receptor tyrosine kinases are involved in regulation of Rho and serum response factor by Galpha12/13 Peptide reporters of kinase activity in whole cell lysates.Endothelial nitric-oxide synthase (eNOS) is activated through G-protein-coupled receptor kinase-interacting protein 1 (GIT1) tyrosine phosphorylation and Src protein Leucine-rich repeat kinase 2: a new player with a familiar theme for Parkinson's disease pathogenesis.The Tec family of cytoplasmic tyrosine kinases: mammalian Btk, Bmx, Itk, Tec, Txk and homologs in other species.Regulation of mitogen-activated protein kinase signaling networks by G protein-coupled receptors.The G protein G alpha12 stimulates Bruton's tyrosine kinase and a rasGAP through a conserved PH/BM domain.A sensitized genetic system for the analysis of murine B lymphocyte signal transduction pathways dependent on Bruton's tyrosine kinase.A multiplicity of muscarinic mechanisms: enough signaling pathways to take your breath away.G protein-coupled receptors and the modification of FcepsilonRI-mediated mast cell activation.Specific antibodies to the external vestibule of voltage-gated potassium channels block current A new non-canonical pathway of Gα(q) protein regulating mitochondrial dynamics and bioenergetics.

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P2860

Direct stimulation of Bruton's tyrosine kinase by G(q)-protein alpha-subunit.

http://www.wikidata.org/entity/Q41090124

description

1997 nî lūn-bûn

@nan

1997年の論文

@ja

1997年論文

@yue

1997年論文

@zh-hant

1997年論文

@zh-hk

1997年論文

@zh-mo

1997年論文

@zh-tw

1997年论文

@wuu

1997年论文

@zh

1997年论文

@zh-cn

name

Direct stimulation of Bruton's tyrosine kinase by G(q)-protein alpha-subunit.

@en

type

label

Direct stimulation of Bruton's tyrosine kinase by G(q)-protein alpha-subunit.

@en

prefLabel

Direct stimulation of Bruton's tyrosine kinase by G(q)-protein alpha-subunit.

@en

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Direct stimulation of Bruton's tyrosine kinase by G(q)-protein alpha-subunit.

@en

P2093

Bence K

http://www.w3.org/2001/XMLSchema#string

Huang XY

http://www.w3.org/2001/XMLSchema#string

Kozasa T

http://www.w3.org/2001/XMLSchema#string

Ma W

http://www.w3.org/2001/XMLSchema#string

P2860

Regulatory intramolecular association in a tyrosine kinase of the Tec family

Regulation of polyphosphoinositide-specific phospholipase C activity by purified Gq.

A MAP kinase targeted by endotoxin and hyperosmolarity in mammalian cells

Regulation of Btk function by a major autophosphorylation site within the SH3 domain

Chemotactic peptide N-formyl-met-leu-phe activation of p38 mitogen-activated protein kinase (MAPK) and MAPK-activated protein kinase-2 in human neutrophils

G proteins: transducers of receptor-generated signals

Protein-tyrosine kinases

Isolation of cDNA clones that encode active protein-tyrosine kinases using antibodies against phosphotyrosine.

Activation of Tsk and Btk tyrosine kinases by G protein beta gamma subunits

Purification and characterization of recombinant human p50csk protein-tyrosine kinase from an Escherichia coli expression system overproducing the bacterial chaperones GroES and GroEL.

P2888

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296-299

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scholarly article

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10.1038/38520

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6648

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P478

389

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1997-09-01T00:00:00Z

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1007493447

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9305846

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