UHRF1 promotes breast cancer progression by suppressing KLF17 expression by hypermethylating its promoter

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Panomics for Precision Medicine.

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UHRF1 promotes breast cancer progression by suppressing KLF17 expression by hypermethylating its promoter

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2017 nî lūn-bûn

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2017年の論文

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2017年論文

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2017年論文

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UHRF1 promotes breast cancer p ...... hypermethylating its promoter

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UHRF1 promotes breast cancer p ...... hypermethylating its promoter

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UHRF1 promotes breast cancer p ...... hypermethylating its promoter

@en

P1476

UHRF1 promotes breast cancer p ...... hypermethylating its promoter

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P2093

He-Fen Sun

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Liang-Dong Li

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Shui-Ping Gao

http://www.w3.org/2001/XMLSchema#string

Wei Jin

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Wen-Yan Fu

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P2860

The interaction of the SRA domain of ICBP90 with a novel domain of DNMT1 is involved in the regulation of VEGF gene expression

ICBP90, a novel methyl K9 H3 binding protein linking protein ubiquitination with heterochromatin formation

ICBP90, an E2F-1 target, recruits HDAC1 and binds to methyl-CpG through its SRA domain

Np95 interacts with de novo DNA methyltransferases, Dnmt3a and Dnmt3b, and mediates epigenetic silencing of the viral CMV promoter in embryonic stem cells

UHRF1 plays a role in maintaining DNA methylation in mammalian cells

Np95 is a histone-binding protein endowed with ubiquitin ligase activity

Recognition of hemi-methylated DNA by the SRA protein UHRF1 by a base-flipping mechanism

Recognition of modification status on a histone H3 tail by linked histone reader modules of the epigenetic regulator UHRF1

ICBP90, a novel human CCAAT binding protein, involved in the regulation of topoisomerase IIalpha expression

Down-regulation of nuclear protein ICBP90 by p53/p21Cip1/WAF1-dependent DNA-damage checkpoint signals contributes to cell cycle arrest at G1/S transition

P304

1554-1565

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scholarly article

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P478

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P577

2017-07-01T00:00:00Z

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P698

28744404

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P932

5523035

http://www.w3.org/2001/XMLSchema#string

UHRF1 promotes breast cancer progression by suppressing KLF17 expression by hypermethylating its promoter

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P2860

P2860

UHRF1 promotes breast cancer progression by suppressing KLF17 expression by hypermethylating its promoter

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P1476

P2093

P2860

P304

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P433

P478

P577

P698

P932

P1433

P1476

P2093

P2860

P304

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P433

P478

P577

P698

P932