The telomere lengthening mechanism in telomerase-negative immortal human cells does not involve the telomerase RNA subunit.
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Telomeres in Cancer TherapyHuman Ku70/80 interacts directly with hTR, the RNA component of human telomeraseSpecificity and stoichiometry of subunit interactions in the human telomerase holoenzyme assembled in vivoPurification of proteins associated with specific genomic LocihnRNP A2, a potential ssDNA/RNA molecular adapter at the telomerePolymerization defects within human telomerase are distinct from telomerase RNA and TEP1 bindingTelomerase RNA level limits telomere maintenance in X-linked dyskeratosis congenitatrt-1 is the Caenorhabditis elegans catalytic subunit of telomerase.Y'-Help1, a DNA helicase encoded by the yeast subtelomeric Y' element, is induced in survivors defective for telomerase.Implications of telomeres and telomerase in endometrial pathologyRole of Werner syndrome gene product helicase in carcinogenesis and in resistance to genotoxins by cancer cellsNucleolin interacts with telomeraseA box H/ACA small nucleolar RNA-like domain at the human telomerase RNA 3' endTetrahymena telomerase is active as a monomer.Many disease-associated variants of hTERT retain high telomerase enzymatic activityInventory of telomerase components in human cells reveals multiple subpopulations of hTR and hTERT.Telomerase reverse transcriptase genes identified in Tetrahymena thermophila and Oxytricha trifallax.Assessing telomeric DNA content in pediatric cancers using whole-genome sequencing data.Contributions of differential p53 expression in the spontaneous immortalization of a chicken embryo fibroblast cell line.Telomeric circles are abundant in the stn1-M1 mutant that maintains its telomeres through recombination.Sumoylation of the BLM ortholog, Sgs1, promotes telomere-telomere recombination in budding yeast.A common variant in the telomerase RNA component is associated with short telomere length.Investigation of human telomerase holoenzyme assembly, activity, and processivity using disease-linked subunit variants.Telomere maintenance in telomerase-deficient mouse embryonic stem cells: characterization of an amplified telomeric DNAAttachment of HeT-A sequences to chromosomal termini in Drosophila melanogaster may occur by different mechanisms.Functional multimerization of the human telomerase reverse transcriptase.N-terminal domains of the human telomerase catalytic subunit required for enzyme activity in vivo.Alternative lengthening of telomeres in mammalian cells.Pilocytic astrocytomas have telomere-associated promyelocytic leukemia bodies without alternatively lengthened telomeres.Telomerase-dependent and independent telomere maintenance and its clinical implications in medullary thyroid carcinoma.Artificial human telomeres from DNA nanocircle templatesTelomere dynamics in myelodysplastic syndromes and acute leukemic transformation.Chromosome break-induced DNA replication leads to nonreciprocal translocations and telomere capture.Telomere elongation (Tel), a new mutation in Drosophila melanogaster that produces long telomeres.Enhancer of terminal gene conversion, a new mutation in Drosophila melanogaster that induces telomere elongation by gene conversion.Prognostic significance of telomere maintenance mechanisms in pediatric high-grade gliomas.Direct involvement of the TEN domain at the active site of human telomeraseTelomerase RNA accumulates in Cajal bodies in human cancer cells.The hTERTalpha splice variant is a dominant negative inhibitor of telomerase activityTelomere maintenance and cancer -- look, no telomerase.
P2860
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P1343
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P2860
The telomere lengthening mechanism in telomerase-negative immortal human cells does not involve the telomerase RNA subunit.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
1997年论文
@zh
1997年论文
@zh-cn
name
The telomere lengthening mecha ...... ve the telomerase RNA subunit.
@en
type
label
The telomere lengthening mecha ...... ve the telomerase RNA subunit.
@en
prefLabel
The telomere lengthening mecha ...... ve the telomerase RNA subunit.
@en
P2093
P2860
P4510
P356
P1476
The telomere lengthening mecha ...... ve the telomerase RNA subunit.
@en
P2093
P2860
P304
P356
10.1093/HMG/6.6.921
P577
1997-06-01T00:00:00Z