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TPX2 phosphorylation maintains metaphase spindle length by regulating microtubule flux.Aurora-A-Dependent Control of TACC3 Influences the Rate of Mitotic Spindle AssemblyMolecular mechanism of Aurora A kinase autophosphorylation and its allosteric activation by TPX2Prediction of Functionally Important Phospho-Regulatory Events in Xenopus laevis Oocytes.Aurora-A inactivation causes mitotic spindle pole fragmentation by unbalancing microtubule-generated forcesA functional cooperativity between Aurora A kinase and LIM kinase1: implication in the mitotic processThe nucleoporin ALADIN regulates Aurora A localization to ensure robust mitotic spindle formation.Phosphorylation of MAP65-1 by Arabidopsis Aurora Kinases Is Required for Efficient Cell Cycle Progression.New insights into subcomplex assembly and modifications of centrosomal proteins.NuSAP modulates the dynamics of kinetochore microtubules by attenuating MCAK depolymerisation activity.Functional impact of Aurora A-mediated phosphorylation of HP1γ at serine 83 during cell cycle progressionStathmin and microtubules regulate mitotic entry in HeLa cells by controlling activation of both Aurora kinase A and Plk1.TPX2: of spindle assembly, DNA damage response, and cancer.Aurora A kinase activity is required for localization of TACC3/ch-TOG/clathrin inter-microtubule bridges.Anticancer activity of the Aurora A kinase inhibitor MK-5108 in non-small-cell lung cancer (NSCLC) in vitro as monotherapy and in combination with chemotherapies.Aurora A Phosphorylation of YY1 during Mitosis Inactivates its DNA Binding Activity.The centrosomal adaptor TACC3 and the microtubule polymerase chTOG interact via defined C-terminal subdomains in an Aurora-A kinase-independent manner.The structure of C290A:C393A Aurora A provides structural insights into kinase regulation.Long residence times revealed by Aurora A kinase-targeting fluorescent probes derived from inhibitors MLN8237 and VX-689.Mechanisms of Mitotic Kinase Regulation: A Structural Perspective.TACC3 transcriptionally upregulates E2F1 to promote cell growth and confer sensitivity to cisplatin in bladder cancer.Aurora-A shines on T cell activation through the regulation of Lck.
P2860
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P2860
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
Uncovering new substrates for Aurora A kinase.
@en
type
label
Uncovering new substrates for Aurora A kinase.
@en
prefLabel
Uncovering new substrates for Aurora A kinase.
@en
P2093
P2860
P50
P356
P1433
P1476
Uncovering new substrates for Aurora A kinase.
@en
P2093
Henrik Molina
Roland A Pache
Teresa Sardon
P2860
P304
P356
10.1038/EMBOR.2010.171
P577
2010-11-12T00:00:00Z