Overexpression of the integrin-linked kinase promotes anchorage-independent cell cycle progression.
about
A new focal adhesion protein that interacts with integrin-linked kinase and regulates cell adhesion and spreadingModulation of integrin signal transduction by ILKAP, a protein phosphatase 2C associating with the integrin-linked kinase, ILK1.p27 phosphorylation by Src regulates inhibition of cyclin E-Cdk2The LIM-only protein PINCH directly interacts with integrin-linked kinase and is recruited to integrin-rich sites in spreading cellsNck-2, a novel Src homology2/3-containing adaptor protein that interacts with the LIM-only protein PINCH and components of growth factor receptor kinase-signaling pathwaysPhosphoinositide-3-OH kinase-dependent regulation of glycogen synthase kinase 3 and protein kinase B/AKT by the integrin-linked kinaseIncreased expression of integrin-linked kinase is associated with shorter survival in non-small cell lung cancerSingle and Multiple Gene Manipulations in Mouse Models of Human CancerDysregulation of integrin-linked kinase (ILK) signaling in colonic polyposisIntegrin-linked kinase (ILK) binding to paxillin LD1 motif regulates ILK localization to focal adhesionsCEACAM6 gene silencing impairs anoikis resistance and in vivo metastatic ability of pancreatic adenocarcinoma cellsMMTV mouse models and the diagnostic values of MMTV-like sequences in human breast cancerCyclins: roles in mitogenic signaling and oncogenic transformationIdentification of an interaction between the m-band protein skelemin and beta-integrin subunits. Colocalization of a skelemin-like protein with beta1- and beta3-integrins in non-muscle cellsInhibition of integrin-linked kinase (ILK) suppresses activation of protein kinase B/Akt and induces cell cycle arrest and apoptosis of PTEN-mutant prostate cancer cellsCell adhesion and the integrin-linked kinase regulate the LEF-1 and beta-catenin signaling pathwaysPituitary adenylyl cyclase-activating polypeptide 38 reduces astroglial proliferation by inhibiting the GTPase RhoASubchronic exposure to arsenic through drinking water alters expression of cancer-related genes in rat liverReduced chondrocyte proliferation and chondrodysplasia in mice lacking the integrin-linked kinase in chondrocytesMolecular pathways regulating EGF-induced epithelio-mesenchymal transition in human ovarian surface epitheliumThe cyclin D1 gene is a target of the beta-catenin/LEF-1 pathwayIntegrin-linked kinase controls neurite outgrowth in N1E-115 neuroblastoma cells.Prognostic implications of expression of the cell cycle inhibitor protein p27Kip1.Inositol hexaphosphate suppresses growth and induces apoptosis in prostate carcinoma cells in culture and nude mouse xenograft: PI3K-Akt pathway as potential target.Talin1 promotes tumor invasion and metastasis via focal adhesion signaling and anoikis resistance.Anti-angiogenic therapy induces integrin-linked kinase 1 up-regulation in a mouse model of glioblastomaAnoikis disruption of focal adhesion-Akt signaling impairs renal cell carcinoma.The structural and mechanical complexity of cell-growth control.PI-3 kinase activity is required for epithelial-mesenchymal transformation during palate fusion.Nicotine inhibits palatal fusion and modulates nicotinic receptors and the PI-3 kinase pathway in medial edge epitheliaImpact of PINCH expression on survival in colorectal cancer patients.Cell-extracellular matrix interactions stimulate the AP-1 transcription factor in an integrin-linked kinase- and glycogen synthase kinase 3-dependent mannerArchitectural transcription factor HMGI(Y) promotes tumor progression and mesenchymal transition of human epithelial cells.Molecular dissection of actopaxin-integrin-linked kinase-Paxillin interactions and their role in subcellular localization.Transgenic mouse models of human breast cancer.Silencing of the integrin-linked kinase gene induces the apoptosis in ovarian carcinoma.MicroRNA-mediated upregulation of integrin-linked kinase promotes Src-induced tumor progression.All-trans retinoic acid (ATRA) downregulates MMP-9 by modulating its regulatory moleculesILKAP regulates ILK signaling and inhibits anchorage-independent growth.Beta-parvin inhibits integrin-linked kinase signaling and is downregulated in breast cancer.
P2860
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P2860
Overexpression of the integrin-linked kinase promotes anchorage-independent cell cycle progression.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
1997年论文
@zh
1997年论文
@zh-cn
name
Overexpression of the integrin ...... endent cell cycle progression.
@en
type
label
Overexpression of the integrin ...... endent cell cycle progression.
@en
prefLabel
Overexpression of the integrin ...... endent cell cycle progression.
@en
P2093
P356
P1476
Overexpression of the integrin ...... endent cell cycle progression.
@en
P2093
Leung-Hagesteijn C
Petrocelli T
Slingerland J
P304
13937-13944
P356
10.1074/JBC.272.21.13937
P407
P577
1997-05-01T00:00:00Z