Regression of established tumors expressing P-glycoprotein by combinations of adriamycin, cyclosporin derivatives, and MRK-16 antibodies.
about
Mode of binding of anti-P-glycoprotein antibody MRK-16 to its antigen. A crystallographic and molecular modeling studyThe strong in vivo anti-tumor effect of the UIC2 monoclonal antibody is the combined result of Pgp inhibition and antibody dependent cell-mediated cytotoxicitySuprafenacine, an indazole-hydrazide agent, targets cancer cells through microtubule destabilizationThe co-delivery of a low-dose P-glycoprotein inhibitor with doxorubicin sterically stabilized liposomes against breast cancer with low P-glycoprotein expression.Molecular targeting therapy of cancer: drug resistance, apoptosis and survival signal.Development of inhibitors of ATP-binding cassette drug transporters: present status and challenges.Is resistance useless? Multidrug resistance and collateral sensitivity.Nanomedicinal strategies to treat multidrug-resistant tumors: current progress.Reversal of ATP-binding cassette drug transporter activity to modulate chemoresistance: why has it failed to provide clinical benefit?CJY, an isoflavone, interacts with ATPase of P-glycoprotein in the rat brain microvessel endothelial cells (RBMECs).In vivo model systems in P-glycoprotein-mediated multidrug resistance.Selective tumor sensitization to taxanes with the mAb-drug conjugate cBR96-doxorubicin.Intracellular levels of two cyclosporin derivatives valspodar (PSC 833) and cyclosporin a closely associated with multidrug resistance-modulating activity in sublines of human colorectal adenocarcinoma HCT-15.An anti-GD2 monoclonal antibody enhances apoptotic effects of anti-cancer drugs against small cell lung cancer cells via JNK (c-Jun terminal kinase) activation.Combined therapy with anti-P-glycoprotein antibody and macrophage colony-stimulating factor gene transduction for multiorgan metastases of multidrug-resistant human small cell lung cancer in NK cell-depleted SCID mice.Ex Vivo Cardiotoxicity of Antineoplastic Casiopeinas Is Mediated through Energetic Dysfunction and Triggered Mitochondrial-Dependent Apoptosis.Influence of SDZ-PSC833 on daunorubicin intracellular accumulation in bone marrow specimens from patients with acute myeloid leukaemia.Combination therapy with antibody and interleukin-2 gene transfer against multidrug-resistant cancer cells.
P2860
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P2860
Regression of established tumors expressing P-glycoprotein by combinations of adriamycin, cyclosporin derivatives, and MRK-16 antibodies.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
1997年论文
@zh
1997年论文
@zh-cn
name
Regression of established tumo ...... atives, and MRK-16 antibodies.
@en
type
label
Regression of established tumo ...... atives, and MRK-16 antibodies.
@en
prefLabel
Regression of established tumo ...... atives, and MRK-16 antibodies.
@en
P2093
P356
P1476
Regression of established tumo ...... atives, and MRK-16 antibodies.
@en
P2093
P304
P356
10.1093/JNCI/89.7.512
P407
P577
1997-04-01T00:00:00Z