Sensing muscle ischemia: coincident detection of acid and ATP via interplay of two ion channels.
about
Molecular and functional properties of P2X receptors--recent progress and persisting challengesAcid-sensing ion channels in pain and disease.The functional and anatomical dissection of somatosensory subpopulations using mouse geneticsEvidence for the involvement of ASIC3 in sensory mechanotransduction in proprioceptors.Acid-sensing ion channels (ASICs) are differentially modulated by anions dependent on their subunit compositionMuscle IL1β Drives Ischemic Myalgia via ASIC3-Mediated Sensory Neuron SensitizationIn pursuit of P2X3 antagonists: novel therapeutics for chronic pain and afferent sensitization.Acid mediates a prolonged antinociception via substance P signaling in acid-induced chronic widespread pain.Neuromodulation by extracellular ATP and P2X receptors in the CNS.Roles of ASIC3, TRPV1, and NaV1.8 in the transition from acute to chronic pain in a mouse model of fibromyalgia.Regulation of ATP-gated P2X channels: from redox signaling to interactions with other proteinsSubtype-specific mechanisms for functional interaction between α6β4* nicotinic acetylcholine receptors and P2X receptorsSimultaneous disruption of mouse ASIC1a, ASIC2 and ASIC3 genes enhances cutaneous mechanosensitivity.Algogenic substances and metabolic status in work-related Trapezius Myalgia: a multivariate explorative study.ASIC3 channels integrate agmatine and multiple inflammatory signals through the nonproton ligand sensing domainAnatomical and physiological factors contributing to chronic muscle painSensitization of group III and IV muscle afferents in the mouse after ischemia and reperfusion injury.Autozygome sequencing expands the horizon of human knockout research and provides novel insights into human phenotypic variation.Autonomic responses to exercise: group III/IV muscle afferents and fatigue.A mechanism-based approach to prevention of and therapy for fibromyalgia.Dry needling - peripheral and central considerations.PAP and NT5E inhibit nociceptive neurotransmission by rapidly hydrolyzing nucleotides to adenosineDifferences in metabolite-detecting, adrenergic, and immune gene expression after moderate exercise in patients with chronic fatigue syndrome, patients with multiple sclerosis, and healthy controlsAn antinociceptive role for substance P in acid-induced chronic muscle pain.Neurobiology of panic and pH chemosensation in the brain.Effect of Intramuscular Protons, Lactate, and ATP on Muscle Hyperalgesia in Rats.ASIC3 Is Required for Development of Fatigue-Induced Hyperalgesia.ENaCs and ASICs as therapeutic targets.Increased Interstitial Concentrations of Glutamate and Pyruvate in Vastus Lateralis of Women with Fibromyalgia Syndrome Are Normalized after an Exercise Intervention - A Case-Control Study.Human ASIC3 channel dynamically adapts its activity to sense the extracellular pH in both acidic and alkaline directions.Dual Modulation of Nociception and Cardiovascular Reflexes during Peripheral Ischemia through P2Y1 Receptor-Dependent Sensitization of Muscle Afferents.IB4(+) nociceptors mediate persistent muscle pain induced by GDNF.Acid-sensing ion channels (ASICs) in mouse skeletal muscle afferents are heteromers composed of ASIC1a, ASIC2, and ASIC3 subunits.Non-acidic activation of pain-related Acid-Sensing Ion Channel 3 by lipidsP2X₃ and TRPV1 functionally interact and mediate sensitization of trigeminal sensory neurons.Developmental expression of P2X5 receptors in the mouse prenatal central and peripheral nervous systems.Comprehensive phenotyping of group III and IV muscle afferents in mouse.The fundamental unit of pain is the cell.Mechanism of augmented exercise hyperpnea in chronic heart failure and dead space loading.Acid evoked thermal hyperalgesia involves peripheral P2Y1 receptor mediated TRPV1 phosphorylation in a rodent model of thrombus induced ischemic pain.
P2860
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P2860
Sensing muscle ischemia: coincident detection of acid and ATP via interplay of two ion channels.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
Sensing muscle ischemia: coinc ...... interplay of two ion channels.
@en
type
label
Sensing muscle ischemia: coinc ...... interplay of two ion channels.
@en
prefLabel
Sensing muscle ischemia: coinc ...... interplay of two ion channels.
@en
P2093
P2860
P1433
P1476
Sensing muscle ischemia: coinc ...... interplay of two ion channels
@en
P2093
Edwin W McCleskey
Frank G Williams
John P Adelman
Josephine Marsh-Haffner
Leonardo Fierro
Ligia A Naves
Michelle Knowles
Robert P Elde
Valeria Spelta
Wolfhard Almers
P2860
P304
P356
10.1016/J.NEURON.2010.09.029
P407
P577
2010-11-01T00:00:00Z