Functional properties of two naturally occurring isoforms of the human insulin receptor in Chinese hamster ovary cells.
about
Molecular basis of signaling specificity of insulin and IGF receptors: neglected corners and recent advancesBinding of human, porcine and bovine insulin to insulin receptors from human brain, muscle and adipocytes and to expressed recombinant alternatively spliced insulin receptor isoformsAlternatively spliced variants of the insulin receptor protein. Expression in normal and diabetic human tissuesObesity and cancer, a case for insulin signalingEngineering of insulin receptor isoform-selective insulin analoguesInsulin and insulin like growth factor II endocytosis and signaling via insulin receptor BA comparative structural bioinformatics analysis of the insulin receptor family ectodomain based on phylogenetic information.Hyperinsulinemia is associated with altered insulin receptor mRNA splicing in muscle of the spontaneously obese diabetic rhesus monkey.Insulin receptor variant forms and type 2 diabetes mellitus.Insight into the molecular basis for the kinetic differences between the two insulin receptor isoforms.The neuronal insulin sensitizer dicholine succinate reduces stress-induced depressive traits and memory deficit: possible role of insulin-like growth factor 2.Molecular mechanism of insulin resistance in type 2 diabetes mellitus: role of the insulin receptor variant forms.Apoptosis in the beta cells: cause or consequence of insulin secretion defect in diabetes?The paired basic amino acid-cleaving enzyme 4 (PACE4) is involved in the maturation of insulin receptor isoform B: an opportunity to reduce the specific insulin receptor-dependent effects of insulin-like growth factor 2 (IGF2).Regulation of human insulin receptor RNA splicing in vivo.Insulin receptor isotype expression correlates with risk of non-insulin-dependent diabetes.Isoform-specific insulin receptor signaling involves different plasma membrane domains.The insulin receptor juxtamembrane region contains two independent tyrosine/beta-turn internalization signals.Insulin Receptor Isoform Variations in Prostate Cancer Cells.Deciphering Brain Insulin Receptor and Insulin-Like Growth Factor 1 Receptor Signalling.Small molecule inhibitors of the IGF-1R/IR axis for the treatment of cancer.H2O2 Signalling Pathway: A Possible Bridge between Insulin Receptor and Mitochondria.The B isoform of the insulin receptor signals more efficiently than the A isoform in HepG2 cells.A review of obesity, insulin resistance, and the role of exercise in breast cancer patients.Comparison of the functional insulin binding epitopes of the A and B isoforms of the insulin receptor.Insulin receptor isoforms: an integrated view focused on gestational diabetes mellitus.Correlation of alpha-fetoprotein expression in normal hepatocytes during development with tyrosine phosphorylation and insulin receptor expressionMEK/ERK pathway activation by insulin receptor isoform alteration is associated with the abnormal proliferation and differentiation of intestinal epithelial cells in diabetic mice.Insulin Effects on Survival of Human Multiple Myeloma Cells.Vascular actions of insulin in health and disease.Differential requirements of the MAP kinase and PI3 kinase signaling pathways in Src- versus insulin and IGF-1 receptors-induced growth and transformation of rat intestinal epithelial cells.Structural Perspectives of Insulin Receptor Isoform-Selective Insulin Analogs.Acute Treatment With XMetA Activates Hepatic Insulin Receptors and Lowers Blood Glucose in Normal Mice.Inositol phospho-oligosaccharides from rat fibroblasts and adipocytes stimulate 3-O-methylglucose transport.Characterization of insulin/IGF hybrid receptors: contributions of the insulin receptor L2 and Fn1 domains and the alternatively spliced exon 11 sequence to ligand binding and receptor activation.Mitochondrial H2O2 as an enable signal for triggering autophosphorylation of insulin receptor in neurons.Insulin receptor membrane retention by a traceable chimeric mutant.Bi-directional regulation of brown fat adipogenesis by the insulin receptor.Insulin Receptor Isoforms in Physiology and Disease: An Updated View.Histologic distribution of insulin and glucagon receptors.
P2860
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P2860
Functional properties of two naturally occurring isoforms of the human insulin receptor in Chinese hamster ovary cells.
description
1991 nî lūn-bûn
@nan
1991年の論文
@ja
1991年論文
@yue
1991年論文
@zh-hant
1991年論文
@zh-hk
1991年論文
@zh-mo
1991年論文
@zh-tw
1991年论文
@wuu
1991年论文
@zh
1991年论文
@zh-cn
name
Functional properties of two n ...... n Chinese hamster ovary cells.
@en
type
label
Functional properties of two n ...... n Chinese hamster ovary cells.
@en
prefLabel
Functional properties of two n ...... n Chinese hamster ovary cells.
@en
P2093
P356
P1433
P1476
Functional properties of two n ...... n Chinese hamster ovary cells.
@en
P2093
P304
P356
10.1210/ENDO-129-4-2058
P407
P577
1991-10-01T00:00:00Z