DNA topoisomerase II-dependent cytotoxicity of alkylaminoanthraquinones and their N-oxides.
about
The chemopotentiation of cisplatin by the novel bioreductive drug AQ4NA novel deep red/low infrared fluorescent flow cytometric probe, DRAQ5NO, for the discrimination of intact nucleated cells in apoptotic cell populations.Characteristics of a novel deep red/infrared fluorescent cell-permeant DNA probe, DRAQ5, in intact human cells analyzed by flow cytometry, confocal and multiphoton microscopy.Efficient hypoxic activation of the anticancer agent AQ4N by CYP2S1 and CYP2W1.Bioreductively activated antitumor N-oxides: the case of AQ4N, a unique approach to hypoxia-activated cancer chemotherapy.Emerging DNA topisomerase inhibitors as anticancer drugs.Tumor-activated prodrugs--a new approach to cancer therapy.Enhancement of chemotherapy and radiotherapy of murine tumours by AQ4N, a bioreductively activated anti-tumour agent.Enhancement of the anti-tumour effect of cyclophosphamide by the bioreductive drugs AQ4N and tirapazamine.Targeting the metabolic microenvironment of tumors.Reductive heme-dependent activation of the n-oxide prodrug AQ4N by nitric oxide synthase.Novel rhein analogues as potential anticancer agents.The unidirectional hypoxia-activated prodrug OCT1002 inhibits growth and vascular development in castrate-resistant prostate tumors.Cytochrome P450 2W1 (CYP2W1) - ready for use as the biomarker and drug target for cancer?Bioreductive GDEPT using cytochrome P450 3A4 in combination with AQ4N.
P2860
Q28346061-48279C56-495B-4E00-9B6D-636C8FD9ABD5Q30841008-DE397CF4-4AE5-422F-813D-9A2014DC910EQ30890985-F4641A98-07E4-4C1B-B832-7CF624870D4DQ34127983-88530B2C-0DED-4305-B3F1-7DC33F3ECB0DQ34819107-3C35D394-599F-4A0A-993B-1FE0F86AA91AQ35779294-359408E0-34A2-475B-B197-3492C491717DQ35964429-48A62F2A-5891-4F1E-97EC-AC7B0FF17AB6Q36621020-FFCBC86B-87C2-4314-9930-8946C517A45AQ36621361-59FEECA4-19CA-46D2-B82F-0679A6731549Q37229190-A4035C72-B83F-4FB0-BADA-C988DE64F72BQ37313648-FBE69AAF-80E2-4AFC-ACE2-4CA0B88815FEQ39466917-F4F6EAEA-D68C-4CE8-89DD-9613BD1D7294Q47763534-F8AF468B-EF78-4A39-8DD1-142C5AC9487BQ50485616-979FC7AD-DA81-4419-B5BC-AABE7890BAF6Q51693639-4D096B61-5228-48DA-AB2F-C965E1F9629D
P2860
DNA topoisomerase II-dependent cytotoxicity of alkylaminoanthraquinones and their N-oxides.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
1997年论文
@zh
1997年论文
@zh-cn
name
DNA topoisomerase II-dependent ...... raquinones and their N-oxides.
@en
type
label
DNA topoisomerase II-dependent ...... raquinones and their N-oxides.
@en
prefLabel
DNA topoisomerase II-dependent ...... raquinones and their N-oxides.
@en
P2093
P356
P1476
DNA topoisomerase II-dependent ...... raquinones and their N-oxides.
@en
P2093
P2888
P304
P356
10.1007/S002800050598
P577
1997-01-01T00:00:00Z
P6179
1014932685