Pharmacology of methylglyoxal: formation, modification of proteins and nucleic acids, and enzymatic detoxification--a role in pathogenesis and antiproliferative chemotherapy.
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Fisetin lowers methylglyoxal dependent protein glycation and limits the complications of diabetesMolecular characterization of mammalian dicarbonyl/L-xylulose reductase and its localization in kidneyDopamine dysregulation in a mouse model of paroxysmal nonkinesigenic dyskinesiaOverexpression of glyoxalase-I in bovine endothelial cells inhibits intracellular advanced glycation endproduct formation and prevents hyperglycemia-induced increases in macromolecular endocytosisGLO1-A novel amplified gene in human cancerTrypanothione-dependent glyoxalase I in Trypanosoma cruziAntioxidant defense in Plasmodium falciparum--data mining of the transcriptomeContribution of the toxic advanced glycation end-products-receptor axis in nonalcoholic steatohepatitis-related hepatocellular carcinomaRole of advanced glycation end products in cellular signalingRole of methylglyoxal in Alzheimer's diseaseA metabolomic analysis of omega-3 fatty acid-mediated attenuation of western diet-induced nonalcoholic steatohepatitis in LDLR-/- miceCharacterization of the glyoxalases of the malarial parasite Plasmodium falciparum and comparison with their human counterpartsMice lacking the β2 adrenergic receptor have a unique genetic profile before and after focal brain ischaemiaHydrogen sulfide releasing aspirin, ACS14, attenuates high glucose-induced increased methylglyoxal and oxidative stress in cultured vascular smooth muscle cellsEvidence Against a Role for the Parkinsonism-associated Protein DJ-1 in Methylglyoxal DetoxificationDistinct subcellular localization in the cytosol and apicoplast, unexpected dimerization and inhibition of Plasmodium falciparum glyoxalasesMethylglyoxal modifies heat shock protein 27 in glomerular mesangial cells.The sour side of neurodegenerative disorders: the effects of protein glycation.Reactive intermediates: molecular and MS-based approaches to assess the functional significance of chemical-protein adducts.Apolipoprotein A-I glycation by glucose and reactive aldehydes alters phospholipid affinity but not cholesterol export from lipid-laden macrophages.Identification and characterization of TspA, a major CD4(+) T-cell- and B-cell-stimulating Neisseria-specific antigen.A possible regulatory role of 17beta-estradiol and tamoxifen on glyoxalase I and glyoxalase II genes expression in MCF7 and BT20 human breast cancer cells.Neurotoxicity of advanced glycation end-products for cultured cortical neurons.Proteomic analysis defines altered cellular redox pathways and advanced glycation end-product metabolism in glomeruli of db/db diabetic mice.Glyoxalase I gene deletion mutants of Leishmania donovani exhibit reduced methylglyoxal detoxificationGlo1 inhibitors for neuropsychiatric and anti-epileptic drug developmentMonitoring nonenzymatic glycation of human immunoglobulin G by methylglyoxal and glyoxal: A spectroscopic studyTroglitazone reduces glyoxalase I protein expression in glioma and potentiates the effects of chemotherapeutic agents.The myeloperoxidase system of human phagocytes generates Nepsilon-(carboxymethyl)lysine on proteins: a mechanism for producing advanced glycation end products at sites of inflammation.Proteomic analysis of peach endocarp and mesocarp during early fruit development.Tumor necrosis factor-induced modulation of glyoxalase I activities through phosphorylation by PKA results in cell death and is accompanied by the formation of a specific methylglyoxal-derived AGEConverting GLX2-1 into an active glyoxalase II.Hsp31 of Escherichia coli K-12 is glyoxalase III.LR-90 prevents methylglyoxal-induced oxidative stress and apoptosis in human endothelial cells.Triple negative tumors accumulate significantly less methylglyoxal specific adducts than other human breast cancer subtypesRole for glyoxalase I in Alzheimer's disease.A trypanothione-dependent glyoxalase I with a prokaryotic ancestry in Leishmania majorAdvanced glycoxidation and lipoxidation end products (AGEs and ALEs): an overview of their mechanisms of formation.Cytoplasmic and nuclear anti-apoptotic roles of αB-crystallin in retinal pigment epithelial cellsOxidative stress as a mechanism of added sugar-induced cardiovascular disease.
P2860
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P2860
Pharmacology of methylglyoxal: formation, modification of proteins and nucleic acids, and enzymatic detoxification--a role in pathogenesis and antiproliferative chemotherapy.
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
1996年论文
@zh
1996年论文
@zh-cn
name
Pharmacology of methylglyoxal: ...... ntiproliferative chemotherapy.
@en
type
label
Pharmacology of methylglyoxal: ...... ntiproliferative chemotherapy.
@en
prefLabel
Pharmacology of methylglyoxal: ...... ntiproliferative chemotherapy.
@en
P1433
P1476
Pharmacology of methylglyoxal: ...... antiproliferative chemotherapy
@en
P2093
Thornalley PJ
P304
P356
10.1016/0306-3623(95)02054-3
P577
1996-06-01T00:00:00Z