Evolution of amber suppressor tRNAs for efficient bacterial production of proteins containing nonnatural amino acids.
about
Using protein backbone mutagenesis to dissect the link between ion occupancy and C-type inactivation in K+ channelsChoosing an effective protein bioconjugation strategyBeyond the canonical 20 amino acids: expanding the genetic lexiconEnzymatic labeling of proteins: techniques and approachesExpanding the genetic code of mammalian cells.A highly efficient catalyst for oxime ligation and hydrazone-oxime exchange suitable for bioconjugation.Role of tRNA orthogonality in an expanded genetic code.Evolution of multiple, mutually orthogonal prolyl-tRNA synthetase/tRNA pairs for unnatural amino acid mutagenesis in Escherichia coli.Genetically encoded libraries of nonstandard peptides.An expanded genetic code in mammalian cells with a functional quadruplet codon.Tuning the affinity of aminoacyl-tRNA to elongation factor Tu for optimal decodingFunctional consequences of T-stem mutations in E. coli tRNAThrUGU in vitro and in vivo.Fine-tuning interaction between aminoacyl-tRNA synthetase and tRNA for efficient synthesis of proteins containing unnatural amino acids.Histidine 66 in Escherichia coli elongation factor tu selectively stabilizes aminoacyl-tRNAs.Optimisation of a system for the co-translational incorporation of a keto amino acid and its application to a tumour-specific Anticalin.Rationally evolving tRNAPyl for efficient incorporation of noncanonical amino acidsCell-free co-production of an orthogonal transfer RNA activates efficient site-specific non-natural amino acid incorporation.Enhanced yield of recombinant proteins with site-specifically incorporated unnatural amino acids using a cell-free expression system.Improved Incorporation of Noncanonical Amino Acids by an Engineered tRNA(Tyr) Suppressor.In vivo incorporation of multiple noncanonical amino acids into proteins.Making connections--strategies for single molecule fluorescence biophysics.Systematic Evolution and Study of UAGN Decoding tRNAs in a Genomically Recoded Bacteria.Development of an Unnatural Amino Acid Incorporation System in the Actinobacterial Natural Product Producer Streptomyces venezuelae ATCC 15439.Site-specific fluorescent labeling of nascent proteins on the translating ribosome.Probing unnatural amino acid integration into enhanced green fluorescent protein by genetic code expansion with a high-throughput screening platform.Expanding the genetic code of Escherichia coli with phosphotyrosine.The central role of tRNA in genetic code expansion.Highly reproductive Escherichia coli cells with no specific assignment to the UAG codon.Multiple site-selective insertions of noncanonical amino acids into sequence-repetitive polypeptides.Structure-based non-canonical amino acid design to covalently crosslink an antibody-antigen complex.Genetically Incorporating Two Distinct Post-translational Modifications into One Protein Simultaneously.Designer tRNAs for efficient incorporation of non-canonical amino acids by the pyrrolysine system in mammalian cells.Enzyme stabilization via computationally guided protein stapling.Continuous directed evolution of aminoacyl-tRNA synthetases.tRNAPyl: Structure, function, and applications.Photoactivatable Mussel-Based Underwater Adhesive Proteins by an Expanded Genetic Code.Intriguing cellular processing of a fluorinated amino acid during protein biosynthesis in Escherichia coli.Two-Tier Screening Platform for Directed Evolution of Aminoacyl-tRNA Synthetases with Enhanced Stop Codon Suppression Efficiency.Playing with the molecules of life.Expanded Genetic Codes Create New Mutational Routes to Rifampicin Resistance in Escherichia coli.
P2860
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P2860
Evolution of amber suppressor tRNAs for efficient bacterial production of proteins containing nonnatural amino acids.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
2009年论文
@zh
2009年论文
@zh-cn
name
Evolution of amber suppressor ...... aining nonnatural amino acids.
@en
type
label
Evolution of amber suppressor ...... aining nonnatural amino acids.
@en
prefLabel
Evolution of amber suppressor ...... aining nonnatural amino acids.
@en
P2093
P2860
P356
P1476
Evolution of amber suppressor ...... aining nonnatural amino acids.
@en
P2093
Charles E Melançon
Hyun Soo Lee
Jiantao Guo
Peter G Schultz
P2860
P304
P356
10.1002/ANIE.200904035
P407
P50
P577
2009-01-01T00:00:00Z