Follitropin signal transduction: alternative splicing of the FSH receptor gene produces a dominant negative form of receptor which inhibits hormone action.
about
Dominant-negative mutations in the G-protein-coupled alpha-factor receptor map to the extracellular ends of the transmembrane segments.Molecular cloning of the mouse follicle-stimulating hormone receptor complementary deoxyribonucleic acid: functional expression of alternatively spliced variants and receptor inactivation by a C566T transition in exon 7 of the coding sequenceImpairing follicle-stimulating hormone (FSH) signaling in vivo: targeted disruption of the FSH receptor leads to aberrant gametogenesis and hormonal imbalanceDominant negative isoform of rat norepinephrine transporter produced by alternative RNA splicingAlternative splicing converts the G-protein coupled follitropin receptor gene into a growth factor type I receptor: implications for pleiotropic actions of the hormone.Identification and in vitro characterization of follicle stimulating hormone (FSH) receptor variants associated with abnormal ovarian response to FSHDominant negative effects of human follicle-stimulating hormone receptor expression-deficient mutants on wild-type receptor cell surface expression. Rescue of oligomerization-dependent defective receptor expression by using cognate decoys.Follicle-stimulating hormone receptor (FSHR) alternative skipping of exon 2 or 3 affects ovarian response to FSHDominant-negative activity of an alpha(1B)-adrenergic receptor signal-inactivating point mutation.Effect of luteinizing hormone-induced prohibitin and matrix metalloproteinases on ovarian epithelial tumor cell proliferation.Follice-stimulating hormone receptor forms oligomers and shows evidence of carboxyl-terminal proteolytic processing.Extragonadal FSH receptor: is it real?Current concepts of follicle-stimulating hormone receptor gene regulationFSH stimulates ovarian cancer cell growth by action on growth factor variant receptorThe molecular basis of impaired follicle-stimulating hormone action: evidence from human mutations and mouse modelsFollicular expression of follicle stimulating hormone receptor variants in the eweDifferential action of glycoprotein hormones: significance in cancer progression.Molecular cloning, structure, and expression of a testicular follitropin receptor with selective alteration in the carboxy terminus that affects signaling function.The Follitropin Receptor: Matching Structure and Function.Follicle-Stimulating Hormone Receptor (FSHR): A Promising Tool in Oncology?Identification of two novel, alternatively spliced mRNA transcripts of the human follicle-stimulating hormone receptor.Fertility-disrupting potential of synthetic peptides derived from the beta-subunit of follicle-stimulating hormone.Structure and expression of the follicle-stimulating hormone receptor gene in a marsupial,Macropus eugenii
P2860
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P2860
Follitropin signal transduction: alternative splicing of the FSH receptor gene produces a dominant negative form of receptor which inhibits hormone action.
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
1996年论文
@zh
1996年论文
@zh-cn
name
Follitropin signal transductio ...... which inhibits hormone action.
@en
type
label
Follitropin signal transductio ...... which inhibits hormone action.
@en
prefLabel
Follitropin signal transductio ...... which inhibits hormone action.
@en
P2093
P356
P1476
Follitropin signal transductio ...... which inhibits hormone action
@en
P2093
P304
P356
10.1006/BBRC.1996.1419
P50
P577
1996-09-01T00:00:00Z