Molecular cloning, functional expression and chromosomal localization of a human homolog of the cyclic nucleotide-gated ion channel of retinal cone photoreceptors.
about
Cloning, chromosomal localization and functional expression of the gene encoding the alpha-subunit of the cGMP-gated channel in human cone photoreceptorsCyclic nucleotide-gated channel subunit glycosylation regulates matrix metalloproteinase-dependent changes in channel gatingFunctional co-assembly among subunits of cyclic-nucleotide-activated, nonselective cation channels, and across species from nematode to human.Molecular mechanism for 3:1 subunit stoichiometry of rod cyclic nucleotide-gated ion channelsFunctional consequences of progressive cone dystrophy-associated mutations in the human cone photoreceptor cyclic nucleotide-gated channel CNGA3 subunitLigand sensitivity of the 2 subunit from the bovine cone cGMP-gated channel is modulated by protein kinase C but not by calmodulinCloning and immunocytochemical localization of a cyclic nucleotide-gated channel alpha-subunit to all cone photoreceptors in the mouse retinaA cGMP-signaling pathway in a subset of olfactory sensory neuronsMolecular cloning and taste bud-specific expression of a novel cyclic nucleotide-gated channel.Alternative splicing governs cone cyclic nucleotide-gated (CNG) channel sensitivity to regulation by phosphoinositides.Mutating three residues in the bovine rod cyclic nucleotide-activated channel can switch a nucleotide from inactive to active.Functionally important calmodulin-binding sites in both NH2- and COOH-terminal regions of the cone photoreceptor cyclic nucleotide-gated channel CNGB3 subunit.Achromatopsia-associated mutation in the human cone photoreceptor cyclic nucleotide-gated channel CNGB3 subunit alters the ligand sensitivity and pore properties of heteromeric channels.Identification of a domain on the beta-subunit of the rod cGMP-gated cation channel that mediates inhibition by calcium-calmodulin.Inherited macular degeneration-associated mutations in CNGB3 increase the ligand sensitivity and spontaneous open probability of cone cyclic nucleotide-gated channelsMatrix metalloproteinase-9 and -2 enhance the ligand sensitivity of photoreceptor cyclic nucleotide-gated channels.Cyclic nucleotide-gated channels on the flagellum control Ca2+ entry into spermMolecular determinants of the modulation of cyclic nucleotide-activated channels by calmodulin.CNGA3 achromatopsia-associated mutation potentiates the phosphoinositide sensitivity of cone photoreceptor CNG channels by altering intersubunit interactionsNative cone photoreceptor cyclic nucleotide-gated channel is a heterotetrameric complex comprising both CNGA3 and CNGB3: a study using the cone-dominant retina of Nrl-/- mice.Impaired cone function and cone degeneration resulting from CNGB3 deficiency: down-regulation of CNGA3 biosynthesis as a potential mechanism.Retinitis pigmentosa: rod photoreceptor rescue by a calcium-channel blocker in the rd mouse.CNGA3 is expressed in inner ear hair cells and binds to an intracellular C-terminus domain of EMILIN1.Fluorescence Titrations to Determine the Binding Affinity of Cyclic Nucleotides to SthK Ion Channels
P2860
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P2860
Molecular cloning, functional expression and chromosomal localization of a human homolog of the cyclic nucleotide-gated ion channel of retinal cone photoreceptors.
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
1996年论文
@zh
1996年论文
@zh-cn
name
Molecular cloning, functional ...... f retinal cone photoreceptors.
@en
type
label
Molecular cloning, functional ...... f retinal cone photoreceptors.
@en
prefLabel
Molecular cloning, functional ...... f retinal cone photoreceptors.
@en
P2093
P2860
P1433
P1476
Molecular cloning, functional ...... f retinal cone photoreceptors.
@en
P2093
P2860
P304
P356
10.1016/0014-5793(96)00889-7
P407
P577
1996-09-01T00:00:00Z