Galpha12 differentially regulates Na+-H+ exchanger isoforms.
about
A calcineurin homologous protein inhibits GTPase-stimulated Na-H exchangekappa Opioid receptor interacts with Na(+)/H(+)-exchanger regulatory factor-1/Ezrin-radixin-moesin-binding phosphoprotein-50 (NHERF-1/EBP50) to stimulate Na(+)/H(+) exchange independent of G(i)/G(o) proteinsIdentification of Galpha13 as one of the G-proteins that couple to human platelet thromboxane A2 receptorsInteraction of G alpha(12) with G alpha(13) and G alpha(q) signaling pathwaysSequential activation of heterotrimeric and monomeric G proteins mediates PLD activity in smooth muscle.Acylation of Galpha(13) is important for its interaction with thrombin receptor, transforming activity and actin stress fiber formation.Identification of a prostate-specific G-protein coupled receptor in prostate cancer.GPR56 in cancer progression: current status and future perspective.RhoA Kinase (Rock) and p90 Ribosomal S6 Kinase (p90Rsk) phosphorylation of the sodium hydrogen exchanger (NHE1) is required for lysophosphatidic acid-induced transport, cytoskeletal organization and migration.A role for Galpha12/Galpha13 in p120ctn regulation.Selective agonism in somatostatin receptor signaling and regulation.G protein regulation of MAPK networks.Na-H exchange acts downstream of RhoA to regulate integrin-induced cell adhesion and spreading.Gα12 structural determinants of Hsp90 interaction are necessary for serum response element-mediated transcriptional activation.Inside out: targeting NHE1 as an intracellular and extracellular regulator of cancer progression.Somatostatin, acting at receptor subtype 1, inhibits Rho activity, the assembly of actin stress fibers, and cell migration.Thrombin-induced inhibition of myoblast differentiation is mediated by Gbetagamma.Regulation of NHE3 activity by G protein subunits in renal brush-border membranes.Galpha12 and Galpha13 stimulate Rho-dependent tyrosine phosphorylation of focal adhesion kinase, paxillin, and p130 Crk-associated substrate.Na+/H+ exchangers of mammalian cells.The Na-H exchanger revisited: an update on Na-H exchange regulation and the role of the exchanger in hypertension and cardiac function in health and disease.Rapid activation of sodium-proton exchange and extracellular signal-regulated protein kinase in fibroblasts by G protein-coupled 5-HT1A receptor involves distinct signalling cascades.Identification of a conserved switch residue responsible for selective constitutive activation of the beta2-adrenergic receptor.Protein kinase D inhibits plasma membrane Na(+)/H(+) exchanger activity.Conserved motifs in somatostatin, D2-dopamine, and alpha 2B-adrenergic receptors for inhibiting the Na-H exchanger, NHE1.A cysteine-11 to serine mutant of G alpha12 impairs activation through the thrombin receptor.The alpha-subunit of the heterotrimeric G protein G13 activates a phospholipase D isozyme by a pathway requiring Rho family GTPases.Galpha12 and Galpha13 negatively regulate the adhesive functions of cadherin.International Union of Basic and Clinical Pharmacology. CV. Somatostatin Receptors: Structure, Function, Ligands, and New Nomenclature
P2860
Q24318471-9D8B023E-4F2C-4B77-A6E5-D945203B13D3Q28255347-69C23F39-C6E7-488B-99C9-7DFA2CB7B5C3Q28375485-7128612A-3960-4341-BB42-33875C6A25B7Q28593081-CBAA8319-FAD5-475D-A174-2FB1AEA69FC2Q31919846-8175FFBB-09D4-48AB-A950-04DA15587C2FQ33912114-1D626F69-D811-4514-8849-6788153527F7Q34094393-BCF30A81-69AD-4D25-B8D7-1856D0214C83Q34269343-4CBC213A-BE20-4A37-9826-A79D46CE384DQ35541268-061615AE-73F9-4A60-A994-4D0A9DD93A1DQ36671656-5B930275-BC1B-4404-81DF-419727F4A5CCQ36731235-219FB726-CE3C-4DCE-8F17-C65EEAE97C08Q36819372-AB6A1AF2-627B-4EBB-90B1-AD5AF660D38BQ36901472-EB2242DD-0DE5-492E-96A2-F83E30F6EC0DQ37663374-2003595C-DF4C-4E74-886C-79383774E38BQ38068566-353687FC-774C-478E-B55C-BC0326540ABDQ40727776-0DF94149-1B6C-494F-A7C7-898FF38A819FQ40883072-58CD0F78-AFF8-4A08-B495-60145B61EC2AQ40889016-E5257C5F-4F31-4736-B2F5-ED1ED1AC7958Q41035564-512A3F91-2C3A-4C51-8BCA-9B1B98AB2CC0Q41581776-B04D57F1-2242-4BED-8674-F28B2E14A0AAQ41700674-A9DCEED8-940B-48C3-A4F2-1B634B7AF61DQ42159389-F0FCC65F-0DFB-4F6C-9E5F-7610DA4BD7D1Q42450308-20EE472A-5C1A-45D5-AAAD-2D6605C9A5EFQ42481223-F0B70FFF-E380-4E2A-9EFF-B97503238423Q44302123-F2160DE5-F660-4800-8022-ED55F3E47871Q47851938-337D34E1-94CD-4E15-B35C-3F3A56F297F5Q48502662-D4209E5E-4D21-4BAE-8D79-49687E335505Q52120808-87CCBC70-F040-4A17-BC7B-7971D6B7657DQ57144951-A82EE82E-B658-486A-BA79-43AD933FFFD4
P2860
Galpha12 differentially regulates Na+-H+ exchanger isoforms.
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
1996年论文
@zh
1996年论文
@zh-cn
name
Galpha12 differentially regulates Na+-H+ exchanger isoforms.
@en
type
label
Galpha12 differentially regulates Na+-H+ exchanger isoforms.
@en
prefLabel
Galpha12 differentially regulates Na+-H+ exchanger isoforms.
@en
P2093
P2860
P356
P1476
Galpha12 differentially regulates Na+-H+ exchanger isoforms
@en
P2093
D L Barber
T A Voyno-Yasenetskaya
P2860
P304
22604-22610
P356
10.1074/JBC.271.37.22604
P407
P577
1996-09-01T00:00:00Z