1,N6-ethenodeoxyadenosine, a DNA adduct highly mutagenic in mammalian cells.
about
Mammalian translesion DNA synthesis across an acrolein-derived deoxyguanosine adduct. Participation of DNA polymerase eta in error-prone synthesis in human cellsAlkB reverses etheno DNA lesions caused by lipid oxidation in vitro and in vivoMutational specificity of gamma-radiation-induced guanine-thymine and thymine-guanine intrastrand cross-links in mammalian cells and translesion synthesis past the guanine-thymine lesion by human DNA polymerase etaResponse of human REV1 to different DNA damage: preferential dCMP insertion opposite the lesion.A novel role for transcription-coupled nucleotide excision repair for the in vivo repair of 3,N4-ethenocytosine.Biological properties of single chemical-DNA adducts: a twenty year perspectiveDNA oligomers containing site-specific and stereospecific exocyclic deoxyadenosine adducts of 1,2,3,4-diepoxybutane: synthesis, characterization, and effects on DNA structure.Induction of frameshift and base pair substitution mutations by the major DNA adduct of the endogenous carcinogen malondialdehyde.Alkylpurine-DNA-N-glycosylase knockout mice show increased susceptibility to induction of mutations by methyl methanesulfonate.Oxyradicals and DNA damage.Vinyl chloride: still a cause for concern.Involvement of oxidatively damaged DNA and repair in cancer development and aging.Mutagenic potency of Helicobacter pylori in the gastric mucosa of mice is determined by sex and duration of infection.Critical role of DNA intercalation in enzyme-catalyzed nucleotide flippingHighly mutagenic exocyclic DNA adducts are substrates for the human nucleotide incision repair pathway.Genetic effects of oxidative DNA damages: comparative mutagenesis of the imidazole ring-opened formamidopyrimidines (Fapy lesions) and 8-oxo-purines in simian kidney cells.Kinetic mechanism for the flipping and excision of 1,N(6)-ethenoadenine by AlkA.An organizational approach for the assessment of DNA adduct data in risk assessment: case studies for aflatoxin B1, tamoxifen and vinyl chloride.Mechanism of 1,N2-etheno-2'-deoxyguanosine formation from epoxyaldehydesSite specific synthesis and polymerase bypass of oligonucleotides containing a 6-hydroxy-3,5,6,7-tetrahydro-9H-imidazo[1,2-a]purin-9-one base, an intermediate in the formation of 1,N2-etheno-2'-deoxyguanosine.Analysis of DNA adducts from chemical carcinogens and lipid peroxidation using liquid chromatography and electrospray mass spectrometry.Replicative bypass of abasic site in Escherichia coli and human cells: similarities and differencesThe generation of carcinogenic etheno-DNA adducts in the liver of patients with nonalcoholic fatty liver diseaseDifferential repair of etheno-DNA adducts by bacterial and human AlkB proteinsVinyl chloride-a classical industrial toxicant of new interest.3,N4-ethenocytosine, a highly mutagenic adduct, is a primary substrate for Escherichia coli double-stranded uracil-DNA glycosylase and human mismatch-specific thymine-DNA glycosylase.AlkB homologue 2-mediated repair of ethenoadenine lesions in mammalian DNA.Inhibition of DNA replication fork progression and mutagenic potential of 1, N6-ethenoadenine and 8-oxoguanine in human cell extracts.Mutagenicity in Escherichia coli of the major DNA adduct derived from the endogenous mutagen malondialdehyde.XRCC1 and base excision repair balance in response to nitric oxideOxidative stress-induced 1, N6-ethenodeoxyadenosine adduct formation contributes to hepatocarcinogenesis.Occurrence and Comparative Toxicity of Haloacetaldehyde Disinfection Byproducts in Drinking WaterDNA damage induced by chronic inflammation contributes to colon carcinogenesis in miceBase excision repair deficient mice lacking the Aag alkyladenine DNA glycosylase.Direct repair of the exocyclic DNA adduct 1,N6-ethenoadenine by the DNA repair AlkB proteins.Oxidative stress and HPV carcinogenesis.Structural and Kinetic Analysis of Miscoding Opposite the DNA Adduct 1,N6-Ethenodeoxyadenosine by Human Translesion DNA Polymerase η.Damage of DNA and proteins by major lipid peroxidation products in genome stability.The role of reactive oxygen species (ROS) and cytochrome P-450 2E1 in the generation of carcinogenic etheno-DNA adducts.1,N(2)-ethenoguanine, a mutagenic DNA adduct, is a primary substrate of Escherichia coli mismatch-specific uracil-DNA glycosylase and human alkylpurine-DNA-N-glycosylase.
P2860
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P2860
1,N6-ethenodeoxyadenosine, a DNA adduct highly mutagenic in mammalian cells.
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
1996年论文
@zh
1996年论文
@zh-cn
name
1,N6-ethenodeoxyadenosine, a DNA adduct highly mutagenic in mammalian cells.
@en
type
label
1,N6-ethenodeoxyadenosine, a DNA adduct highly mutagenic in mammalian cells.
@en
prefLabel
1,N6-ethenodeoxyadenosine, a DNA adduct highly mutagenic in mammalian cells.
@en
P356
P1433
P1476
1,N6-ethenodeoxyadenosine, a DNA adduct highly mutagenic in mammalian cells.
@en
P2093
P304
11487-11492
P356
10.1021/BI960170H
P407
P577
1996-09-01T00:00:00Z