Global and local determinants for the kinetics of interleukin-4/interleukin-4 receptor alpha chain interaction. A biosensor study employing recombinant interleukin-4-binding protein.
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BMP-2 antagonists emerge from alterations in the low-affinity binding epitope for receptor BMPR-IIStructural and biophysical studies of the human IL-7/IL-7Ralpha complexElectrostatic interactions in the binding pathway of a transient protein complex studied by NMR and isothermal titration calorimetry.A modular interface of IL-4 allows for scalable affinity without affecting specificity for the IL-4 receptor.Predicting Protein-protein Association Rates using Coarse-grained Simulation and Machine Learning.De novo design of an IL-4 antagonist and its structure at 1.9 A.Fundamental aspects of protein-protein association kineticsEffects of the geometry of the immunological synapse on the delivery of effector molecules.Overexpression of interleukin-4 in lungs of mice impairs elimination of Histoplasma capsulatum.Mechanistic diversity of cytokine receptor signaling across cell membranes.Poisson-Boltzmann calculations of nonspecific salt effects on protein-protein binding free energies.Prediction of salt and mutational effects on the association rate of U1A protein and U1 small nuclear RNA stem/loop II.Rate theories for biologistsTuning sensitivity to IL-4 and IL-13: differential expression of IL-4Ralpha, IL-13Ralpha1, and gammac regulates relative cytokine sensitivity.Structural biology of shared cytokine receptors.Receptor oligomerization and beyond: a case study in bone morphogenetic proteins.Evolution of IL4 and pathogen antagonism.Structural insights into the common γ-chain family of cytokines and receptors from the interleukin-7 pathway.A murine interleukin-4 antagonistic mutant protein completely inhibits interleukin-4-induced cell proliferation, differentiation, and signal transduction.A biosensor study indicating that entropy, electrostatics, and receptor glycosylation drive the binding interaction between interleukin-7 and its receptor.NOD-scid IL2R γnull mice engrafted with human peripheral blood mononuclear cells as a model to test therapeutics targeting human signaling pathways.Electrostatic rate enhancement and transient complex of protein-protein association.Association and dissociation kinetics of colicin E3 and immunity protein 3: convergence of theory and experimentSite2 binding energetics of the regulatory step of growth hormone-induced receptor homodimerization.Induction of oxazolone-mediated features of atopic dermatitis in NOD-scid IL2Rγ(null) mice engrafted with human peripheral blood mononuclear cellsRemarkably fast coupled folding and binding of the intrinsically disordered transactivation domain of cMyb to CBP KIX.Cooperativity of binding epitopes and receptor chains in the BMP/TGFbeta superfamily.Electrostatic Interactions in Protein Structure, Folding, Binding, and Condensation.IL4 binds IL4R:JAK2A multiscale model for simulating binding kinetics of proteins with flexible linkers.Binding of small peptides to immobilized antibodies: kinetic analysis by surface plasmon resonance.The Heparan Sulfate Binding Sequence of Interferon-γ Increased the On Rate of the Interferon-γ-Interferon-γ Receptor Complex Formation
P2860
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P2860
Global and local determinants for the kinetics of interleukin-4/interleukin-4 receptor alpha chain interaction. A biosensor study employing recombinant interleukin-4-binding protein.
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
1996年论文
@zh
1996年论文
@zh-cn
name
Global and local determinants ...... interleukin-4-binding protein.
@en
type
label
Global and local determinants ...... interleukin-4-binding protein.
@en
prefLabel
Global and local determinants ...... interleukin-4-binding protein.
@en
P2093
P1433
P1476
Global and local determinants ...... interleukin-4-binding protein.
@en
P2093
P304
P356
10.1111/J.1432-1033.1996.0252H.X
P407
P577
1996-08-01T00:00:00Z