The cytoplasmic domain of the hyaluronan receptor for endocytosis (HARE) contains multiple endocytic motifs targeting coated pit-mediated internalization
about
AMN directs endocytosis of the intrinsic factor-vitamin B(12) receptor cubam by engaging ARH or Dab2Murine homologue of the human KIAA1199 is implicated in hyaluronan binding and depolymerizationKIAA1199, a deafness gene of unknown function, is a new hyaluronan binding protein involved in hyaluronan depolymerizationThe Importance of CD44 as a Stem Cell Biomarker and Therapeutic Target in CancerRoles of Proteoglycans and Glycosaminoglycans in Wound Healing and FibrosisN-Glycans on the link domain of human HARE/Stabilin-2 are needed for hyaluronan binding to purified ecto-domain, but not for cellular endocytosis of hyaluronanA hyaluronan receptor for endocytosis (HARE) link domain N-glycan is required for extracellular signal-regulated kinase (ERK) and nuclear factor-κB (NF-κB) signaling in response to the uptake of hyaluronan but not heparin, dermatan sulfate, or acetyHARE-Mediated Endocytosis of Hyaluronan and Heparin Is Targeted by Different Subsets of Three Endocytic Motifs.Association between KIAA1199 overexpression and tumor invasion, TNM stage, and poor prognosis in colorectal cancer.Inhibition of Stabilin-2 elevates circulating hyaluronic acid levels and prevents tumor metastasisActivation of ERK and NF-κB during HARE-Mediated Heparin Uptake Require Only One of the Four Endocytic Motifs.Regulation of Hyaluronan (HA) Metabolism Mediated by HYBID (Hyaluronan-binding Protein Involved in HA Depolymerization, KIAA1199) and HA Synthases in Growth Factor-stimulated Fibroblasts.The hyaluronan receptor for endocytosis (HARE) activates NF-κB-mediated gene expression in response to 40-400-kDa, but not smaller or larger, hyaluronans.Hyaluronic acid receptor for endocytosis (HARE)-mediated endocytosis of hyaluronan, heparin, dermatan sulfate, and acetylated low density lipoprotein (AcLDL), but not chondroitin sulfate types A, C, D, or E, activates NF-κB-regulated gene expressionThe dynamic metabolism of hyaluronan regulates the cytosolic concentration of UDP-GlcNAc.N-Terminal signal sequence is required for cellular trafficking and hyaluronan-depolymerization of KIAA1199.Hyaluronan-CD44 Interactions in Cancer: Paradoxes and PossibilitiesChain gangs: new aspects of hyaluronan metabolism.Systemic blockade of the hyaluronan receptor for endocytosis prevents lymph node metastasis of prostate cancer.Receptor-Mediated Uptake of Phosphorothioate Antisense Oligonucleotides in Different Cell Types of the Liver.
P2860
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P2860
The cytoplasmic domain of the hyaluronan receptor for endocytosis (HARE) contains multiple endocytic motifs targeting coated pit-mediated internalization
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
The cytoplasmic domain of the ...... d pit-mediated internalization
@en
type
label
The cytoplasmic domain of the ...... d pit-mediated internalization
@en
prefLabel
The cytoplasmic domain of the ...... d pit-mediated internalization
@en
P2093
P2860
P356
P1476
The cytoplasmic domain of the ...... d pit-mediated internalization
@en
P2093
Edward N Harris
Janet A Weigel
Madhu S Pandey
Paul H Weigel
P2860
P304
21453-21461
P356
10.1074/JBC.M800886200
P407
P577
2008-06-06T00:00:00Z