Stimulation of luteinizing hormone beta gene promoter activity by the orphan nuclear receptor, steroidogenic factor-1.
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Ptx1 regulates SF-1 activity by an interaction that mimics the role of the ligand-binding domainEgr-1 is a downstream effector of GnRH and synergizes by direct interaction with Ptx1 and SF-1 to enhance luteinizing hormone beta gene transcriptionSF-1 a key player in the development and differentiation of steroidogenic tissuesFox tales: regulation of gonadotropin gene expression by forkhead transcription factorsModulation of human luteinizing hormone beta gene transcription by MIP-2ATpit determines alternate fates during pituitary cell differentiationKisspeptin regulates gonadotropin genes via immediate early gene induction in pituitary gonadotropesNR5A2 regulates Lhb and Fshb transcription in gonadotrope-like cells in vitro, but is dispensable for gonadotropin synthesis and fertility in vivo.CREB binding protein (CBP) activation is required for luteinizing hormone beta expression and normal fertility in miceHormones in synergy: regulation of the pituitary gonadotropin genes.Minireview: steroidogenic factor 1: its roles in differentiation, development, and diseasePituitary homeobox 2 regulates adrenal4 binding protein/steroidogenic factor-1 gene transcription in the pituitary gonadotrope through interaction with the intronic enhancerNuclear receptor DAX-1 recruits nuclear receptor corepressor N-CoR to steroidogenic factor 1Susceptible periods during embryogenesis of the heart and endocrine glandsHuman NR5A1/SF-1 mutations show decreased activity on BDNF (brain-derived neurotrophic factor), an important regulator of energy balance: testing impact of novel SF-1 mutations beyond steroidogenesis.An Otx-related homeodomain protein binds an LHbeta promoter element important for activation during gonadotrope maturation.Different signaling pathways control acute induction versus long-term repression of LHbeta transcription by GnRHTissue-specific expression of squirrel monkey chorionic gonadotropin.Essential role of the homeodomain for pituitary homeobox 1 activation of mouse gonadotropin-releasing hormone receptor gene expression through interactions with c-Jun and DNA.Nuclear Receptors in Regulation of Mouse ES Cell Pluripotency and DifferentiationDAX-1 inhibits SF-1-mediated transactivation via a carboxy-terminal domain that is deleted in adrenal hypoplasia congenita.Nuclear receptor steroidogenic factor 1 directs embryonic stem cells toward the steroidogenic lineageGnRH Pulse Frequency Control of Fshb Gene Expression Is Mediated via ERK1/2 Regulation of ICERMsx1 homeodomain protein represses the αGSU and GnRH receptor genes during gonadotrope developmentMolecular physiology of pituitary development: signaling and transcriptional networks.Progesterone Inhibits basal and gonadotropin-releasing hormone induction of luteinizing hormone beta-subunit gene expression.Conservation of mechanisms mediating gonadotrophin-releasing hormone 1 stimulation of human luteinizing hormone beta subunit transcription.GnRH pulse frequency-dependent differential regulation of LH and FSH gene expressionGonadotropin-releasing hormone and gonadal steroids regulate transcription factor mRNA expression in primary pituitary and immortalized gonadotrope cells.PPARγ co-activator-1α co-activates steroidogenic factor 1 to stimulate the synthesis of luteinizing hormone and aldosterone.p300 regulates the synergy of steroidogenic factor-1 and early growth response-1 in activating luteinizing hormone-beta subunit gene.Embryonic expression of the luteinizing hormone beta gene appears to be coupled to the transient appearance of p8, a high mobility group-related transcription factor.An NF-Y binding site is important for basal, but not gonadotropin-releasing hormone-stimulated, expression of the luteinizing hormone beta subunit gene.Expression of Ptx1 in the adult rat pituitary glands and pituitary cell lines: hormone-secreting cells and folliculo-stellate cells.Activation of luteinizing hormone beta gene by gonadotropin-releasing hormone requires the synergy of early growth response-1 and steroidogenic factor-1.Identification and characterization of the gonadotropin-releasing hormone response elements in the mouse gonadotropin-releasing hormone receptor gene.Steroidogenic factor-1 and early growth response protein 1 act through two composite DNA binding sites to regulate luteinizing hormone beta-subunit gene expression.Steroidogenic factor-1 is an essential transcriptional activator for gonad-specific expression of promoter I of the rat prolactin receptor gene.Expression of proadrenomedullin derived peptides in the mammalian pituitary: co-localization of follicle stimulating hormone and proadrenomedullin N-20 terminal peptide-like peptide in the same secretory granules of the gonadotropes.Chromatin status and transcription factor binding to gonadotropin promoters in gonadotrope cell lines.
P2860
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P2860
Stimulation of luteinizing hormone beta gene promoter activity by the orphan nuclear receptor, steroidogenic factor-1.
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年学术文章
@wuu
1996年学术文章
@zh-cn
1996年学术文章
@zh-hans
1996年学术文章
@zh-my
1996年学术文章
@zh-sg
1996年學術文章
@yue
1996年學術文章
@zh
1996年學術文章
@zh-hant
name
Stimulation of luteinizing hor ...... eptor, steroidogenic factor-1.
@en
type
label
Stimulation of luteinizing hor ...... eptor, steroidogenic factor-1.
@en
prefLabel
Stimulation of luteinizing hor ...... eptor, steroidogenic factor-1.
@en
P2093
P2860
P356
P1476
Stimulation of luteinizing hor ...... eptor, steroidogenic factor-1.
@en
P2093
P2860
P304
P356
10.1074/JBC.271.12.6645
P407
P577
1996-03-01T00:00:00Z