Phosphorylation of p105 PEST sequence via a redox-insensitive pathway up-regulates processing of p50 NF-kappaB.
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Physical interaction of the bHLH LYL1 protein and NF-kappaB1 p105Shared pathways of IkappaB kinase-induced SCF(betaTrCP)-mediated ubiquitination and degradation for the NF-kappaB precursor p105 and IkappaBalphaIdentification of a conserved negative regulatory sequence that influences the leukemogenic activity of NOTCH1SCF(beta)(-TrCP) ubiquitin ligase-mediated processing of NF-kappaB p105 requires phosphorylation of its C-terminus by IkappaB kinaseThe Ubiquitination of NF-κB Subunits in the Control of TranscriptionNF-κB, the first quarter-century: remarkable progress and outstanding questionsDual effects of IkappaB kinase beta-mediated phosphorylation on p105 Fate: SCF(beta-TrCP)-dependent degradation and SCF(beta-TrCP)-independent processingbetaTrCP-mediated proteolysis of NF-kappaB1 p105 requires phosphorylation of p105 serines 927 and 932.Nuclear translocation of green fluorescent protein-nuclear factor kappaB with a distinct lag time in living cells.Persistent activation of NF-kappaB by the tax transforming protein of HTLV-1: hijacking cellular IkappaB kinases.NOD mice are defective in proteasome production and activation of NF-kappaBDeletion analysis of BMI1 oncoprotein identifies its negative regulatory domainEnzymes catalyzing ubiquitination and proteolytic processing of the p105 precursor of nuclear factor kappaB1.Cotranslational dimerization of the Rel homology domain of NF-kappaB1 generates p50-p105 heterodimers and is required for effective p50 production.15-Deoxy-Delta 12,14-prostaglandin J2 inhibition of NF-kappaB-DNA binding through covalent modification of the p50 subunit.Functions of NF-kappaB1 and NF-kappaB2 in immune cell biologyInvolvement of Egr-1/RelA synergy in distinguishing T cell activation from tumor necrosis factor-alpha-induced NF-kappa B1 transcription.A comprehensive map of the toll-like receptor signaling network.Reconstitution of the NF-kappa B system in Saccharomyces cerevisiae for isolation of effectors by phenotype modulation.The TGFβ1 pathway is required for NFκB dependent gene expression in mouse keratinocytes.On the segregation of protein ionic residues by charge type.Essential role of human leukocyte antigen-encoded proteasome subunits in NF-kappaB activation and prevention of tumor necrosis factor-alpha-induced apoptosis.Gastric hyperplasia and increased proliferative responses of lymphocytes in mice lacking the COOH-terminal ankyrin domain of NF-kappaB2.Reduced phosphorylation of p50 is responsible for diminished NF-kappaB binding to the major histocompatibility complex class I enhancer in adenovirus type 12-transformed cells.Structural motifs involved in ubiquitin-mediated processing of the NF-kappaB precursor p105: roles of the glycine-rich region and a downstream ubiquitination domain.Processing of p105 is inhibited by docking of p50 active subunits to the ankyrin repeat domain, and inhibition is alleviated by signaling via the carboxyl-terminal phosphorylation/ ubiquitin-ligase binding domain.Selective inhibition of NF-kappaB activation by the flavonoid hepatoprotector silymarin in HepG2. Evidence for different activating pathways.Degradation of proto-oncoprotein c-Rel by the ubiquitin-proteasome pathway.Regulation of estrogenic and nuclear factor kappa B functions by polyamines and their role in polyamine analog-induced apoptosis of breast cancer cells.Ceramide activates NFkappaB by inducing the processing of p105.NF-κB p105 Processing via the Ubiquitin-Proteasome Pathway
P2860
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P2860
Phosphorylation of p105 PEST sequence via a redox-insensitive pathway up-regulates processing of p50 NF-kappaB.
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年学术文章
@wuu
1996年学术文章
@zh-cn
1996年学术文章
@zh-hans
1996年学术文章
@zh-my
1996年学术文章
@zh-sg
1996年學術文章
@yue
1996年學術文章
@zh
1996年學術文章
@zh-hant
name
Phosphorylation of p105 PEST s ...... s processing of p50 NF-kappaB.
@en
type
label
Phosphorylation of p105 PEST s ...... s processing of p50 NF-kappaB.
@en
prefLabel
Phosphorylation of p105 PEST s ...... s processing of p50 NF-kappaB.
@en
P2093
P2860
P356
P1476
Phosphorylation of p105 PEST s ...... s processing of p50 NF-kappaB.
@en
P2093
P2860
P304
P356
10.1074/JBC.271.11.6084
P407
P577
1996-03-01T00:00:00Z