Human 17 beta-hydroxysteroid dehydrogenase type 1 and type 2 isoenzymes have opposite activities in cultured cells and characteristic cell- and tissue-specific expression. - Wikidata - awgldk - TriplyDB

Human 17 beta-hydroxysteroid dehydrogenase type 1 and type 2 isoenzymes have opposite activities in cultured cells and characteristic cell- and tissue-specific expression.

Human 17 beta-hydroxysteroid dehydrogenase type 1 and type 2 isoenzymes have opposite activities in cultured cells and characteristic cell- and tissue-specific expression.

http://www.wikidata.org/entity/Q41216391

about

Structural and biochemical characterization of human orphan DHRS10 reveals a novel cytosolic enzyme with steroid dehydrogenase activity Structure of the ternary complex of human 17beta-hydroxysteroid dehydrogenase type 1 with 3-hydroxyestra-1,3,5,7-tetraen-17-one (equilin) and NADP+Genetic variation in the HSD17B1 gene and risk of prostate cancer.Insights in 17beta-HSD1 enzyme kinetics and ligand binding by dynamic motion investigation Purification, reconstitution, and steady-state kinetics of the trans-membrane 17 beta-hydroxysteroid dehydrogenase 2 17Beta-hydroxysteroid dehydrogenases in human bone cells 17Beta-hydroxysteroid dehydrogenase type 1 and type 2 in human breast carcinoma: a correlation to clinicopathological parameters Novel hydroxysteroid (17beta) dehydrogenase 1 inhibitors reverse estrogen-induced endometrial hyperplasia in transgenic mice Estrogen and androgen-converting enzymes 17β-hydroxysteroid dehydrogenase and their involvement in cancer: with a special focus on 17β-hydroxysteroid dehydrogenase type 1, 2, and breast cancer.Genistein: does it prevent or promote breast cancer?Decreased expression of 17β-hydroxysteroid dehydrogenase type 1 is associated with DNA hypermethylation in colorectal cancer located in the proximal colon.The contribution of 17beta-hydroxysteroid dehydrogenase type 1 to the estradiol-estrone ratio in estrogen-sensitive breast cancer cells Type 2 17-β hydroxysteroid dehydrogenase as a novel target for the treatment of osteoporosis.Hormones and prostate cancer: current perspectives and future directions.New development in intracrinology of breast carcinoma.17beta-Hydroxysteroid dehydrogenases involved in local oestrogen synthesis have prognostic significance in breast cancer.Oestrogen producing enzymes and mammary carcinogenesis: a review.Expression of estrogenicity genes in a lineage cell culture model of human breast cancer progression.17beta-Hydroxysteroid dehydrogenase inhibitors: a patent review.Regulation of 17β-hydroxysteroid dehydrogenases in cancer: regulating steroid receptor at pre-receptor stage.The correlation between the response to progestogen treatment and the expression of progesterone receptor B and 17beta-hydroxysteroid dehydrogenase type 2 in human endometrial carcinoma.Role of Sex Steroids in β Cell Function, Growth, and Survival.17beta-hydroxysteroid dehydrogenase Type 1, and not Type 12, is a target for endocrine therapy of hormone-dependent breast cancer.Gender differences of enzymatic activity and distribution of 17beta-hydroxysteroid dehydrogenase in human skin in vitro.Enzyme inhibitor screening using a homogeneous proximity-based immunoassay for estradiol.17Beta-hydroxysteroid dehydrogenases in normal human mammary epithelial cells and breast tissue.The regulation of hydroxysteroid 17β-dehydrogenase type 1 and 2 gene expression in breast cancer cell lines by estradiol, dihydrotestosterone, microRNAs, and genes related to breast cancer.Cloning of mouse 17beta-hydroxysteroid dehydrogenase type 2, and analysing expression of the mRNAs for types 1, 2, 3, 4 and 5 in mouse embryos and adult tissues.Expression, purification, and characterization of a human recombinant 17beta-hydroxysteroid dehydrogenase type 1 in Escherichia coli.Inhibitors of human and rat testes microsomal 17beta-hydroxysteroid dehydrogenase (17beta-HSD) as potential agents for prostatic cancer.Downregulation of estrogen-metabolizing 17 beta-hydroxysteroid dehydrogenase type 2 expression correlates inversely with Ki67 proliferation marker in colon-cancer development.Amplification of HSD17B1 and ERBB2 in primary breast cancer.Characterization of 17beta-hydroxysteroid dehydrogenase activity in brain tissue: testosterone formation in the human temporal lobe.

P2860

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P2860

Human 17 beta-hydroxysteroid dehydrogenase type 1 and type 2 isoenzymes have opposite activities in cultured cells and characteristic cell- and tissue-specific expression.

http://www.wikidata.org/entity/Q41216391

description

1996 nî lūn-bûn

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1996年の論文

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1996年学术文章

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1996年学术文章

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1996年学术文章

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1996年学术文章

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1996年学术文章

@zh-sg

1996年學術文章

@yue

1996年學術文章

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1996年學術文章

@zh-hant

name

Human 17 beta-hydroxysteroid d ...... nd tissue-specific expression.

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type

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Human 17 beta-hydroxysteroid d ...... nd tissue-specific expression.

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prefLabel

Human 17 beta-hydroxysteroid d ...... nd tissue-specific expression.

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Biochemical Journal

P1476

Human 17 beta-hydroxysteroid d ...... nd tissue-specific expression.

@en

P2093

Isomaa VV

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Miettinen MM

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Mustonen MV

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Poutanen MH

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Vihko RK

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P2860

Male pseudohermaphroditism caused by mutations of testicular 17 beta-hydroxysteroid dehydrogenase 3

Expression cloning and characterization of human 17 beta-hydroxysteroid dehydrogenase type 2, a microsomal enzyme possessing 20 alpha-hydroxysteroid dehydrogenase activity

Regulation of the gene for estrogenic 17-ketosteroid reductase lying on chromosome 17cen----q25

Structure of human estrogenic 17 beta-hydroxysteroid dehydrogenase at 2.20 A resolution

Point mutations define a sequence flanking the AUG initiator codon that modulates translation by eukaryotic ribosomes

Structure of two in tandem human 17 beta-hydroxysteroid dehydrogenase genes

17 beta-Hydroxysteroid dehydrogenase type 2: chromosomal assignment and progestin regulation of gene expression in human endometrium

Oxidized redox state of glutathione in the endoplasmic reticulum

Compartmentalization of type I 17 beta-hydroxysteroid oxidoreductase in the human ovary.

Complete amino acid sequence of human placental 17 beta-hydroxysteroid dehydrogenase deduced from cDNA.

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839-845

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scholarly article

P356

10.1042/BJ3140839

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P478

314 ( Pt 3)

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1996-03-01T00:00:00Z

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14584336

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8615778

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1217133

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