Characterization of deletion and truncation mutants of the rat glucagon receptor. Seven transmembrane segments are necessary for receptor transport to the plasma membrane and glucagon binding.
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Homozygous P86S mutation of the human glucagon receptor is associated with hyperglucagonemia, alpha cell hyperplasia, and islet cell tumorFunctional characterization of mutations in melanocortin-4 receptor associated with human obesityStructure-function of the glucagon receptor family of G protein-coupled receptors: the glucagon, GIP, GLP-1, and GLP-2 receptorsMolecular characterization of a second mouse pancreatic polypeptide receptor and its inactivated human homologueAntibodies against specific extracellular epitopes of the glucagon receptor block glucagon bindingRequirement of N-glycosylation of the prostaglandin E2 receptor EP3beta for correct sorting to the plasma membrane but not for correct folding.N-glycan remodeling on glucagon receptor is an effector of nutrient sensing by the hexosamine biosynthesis pathwayGlucagon receptor activates extracellular signal-regulated protein kinase 1/2 via cAMP-dependent protein kinase.The glucagon-like peptide-2 receptor C terminus modulates beta-arrestin-2 association but is dispensable for ligand-induced desensitization, endocytosis, and G-protein-dependent effector activation.Glucagon receptor gene mutations with hyperglucagonemia but without the glucagonoma syndrome.The Energetics of Streptococcal Enolase Octamer Formation: The Quantitative Contributions of the Last Eight Amino Acids at the Carboxy-Terminus.Glucagon receptor recycling: role of carboxyl terminus, beta-arrestins, and cytoskeletonEvidence that the cysteine-rich domain of Drosophila Frizzled family receptors is dispensable for transducing Wingless.Different domains of the glucagon and glucagon-like peptide-1 receptors provide the critical determinants of ligand selectivityThe isolated N-terminal domain of the glucagon-like peptide-1 (GLP-1) receptor binds exendin peptides with much higher affinity than GLP-1.Truncation releases olfactory receptors from the endoplasmic reticulum of heterologous cells.Identification of an essential amino acid motif within the C terminus of the pituitary adenylate cyclase-activating polypeptide type I receptor that is critical for signal transduction but not for receptor internalization.Oligomer formation of histamine H2 receptors expressed in Sf9 and COS7 cells.Conserved extracellular cysteine residues and cytoplasmic loop-loop interplay are required for functionality of the heptahelical MLO proteinSelective stabilization of the high affinity binding conformation of glucagon receptor by the long splice variant of Galpha(s).Ectopic expression of glucagon receptor in skeletal muscles improves glucose homeostasis in a mouse model of diabetes.Two cytoplasmic loops of the glucagon receptor are required to elevate cAMP or intracellular calcium.O-Glycosylation of G-protein-coupled receptor, octopus rhodopsin. Direct analysis by FAB mass spectrometry.Identification of cytoplasmic domains of hVPAC1 receptor required for activation of adenylyl cyclase. Crucial role of two charged amino acids strictly conserved in class II G protein-coupled receptors.N-Glycosylation of Asparagine 130 in the Extracellular Domain of the Human Calcitonin Receptor Significantly Increases Peptide Hormone Affinity.Histologic distribution of insulin and glucagon receptors.A linkage and cross-sectional study of hypertension and obesity using a poly (A) Alu-repeat polymorphism at the glucagon receptor gene locus (17q25).Genomic organization of the rat pituitary adenylate cyclase-activating polypeptide receptor gene. Alternative splicing within the 5'-untranslated region.The carboxyl terminus of the human calcium receptor. Requirements for cell-surface expression and signal transduction.Mice with Markedly Reduced PACAP (PAC1) Receptor Expression by Targeted Deletion of the Signal Peptide
P2860
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P2860
Characterization of deletion and truncation mutants of the rat glucagon receptor. Seven transmembrane segments are necessary for receptor transport to the plasma membrane and glucagon binding.
description
1995 nî lūn-bûn
@nan
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
1995年论文
@zh
1995年论文
@zh-cn
name
Characterization of deletion a ...... membrane and glucagon binding.
@en
type
label
Characterization of deletion a ...... membrane and glucagon binding.
@en
prefLabel
Characterization of deletion a ...... membrane and glucagon binding.
@en
P2093
P2860
P356
P1476
Characterization of deletion a ...... membrane and glucagon binding.
@en
P2093
Carruthers CJ
Goldsmith PK
Merrifield RB
P2860
P304
27720-27727
P356
10.1074/JBC.270.46.27720
P407
P577
1995-11-01T00:00:00Z