In vivo selection of hematopoietic stem cells transduced at a low multiplicity-of-infection with a foamy viral MGMT(P140K) vector.
about
Towards in vivo amplification: Overcoming hurdles in the use of hematopoietic stem cells in transplantation and gene therapyIn vivo enrichment of genetically manipulated platelets corrects the murine hemophilic phenotype and induces immune tolerance even using a low multiplicity of infectionImaging stem cell-derived persistent foci after in vivo selection of lentiviral MGMT-P140K transduced murine bone marrow cells.Differential Secondary Reconstitution of In Vivo-Selected Human SCID-Repopulating Cells in NOD/SCID versus NOD/SCID/γ chain Mice.Foamy viral vector integration sites in SCID-repopulating cells after MGMTP140K-mediated in vivo selectionOvernight transduction with foamyviral vectors restores the long-term repopulating activity of Fancc-/- stem cells.Amelioration of murine beta-thalassemia through drug selection of hematopoietic stem cells transduced with a lentiviral vector encoding both gamma-globin and the MGMT drug-resistance gene.The Xpc gene markedly affects cell survival in mouse bone marrow.Efficiency and safety of O⁶-methylguanine DNA methyltransferase (MGMT(P140K))-mediated in vivo selection in a humanized mouse modelProgress and prospects: foamy virus vectors enter a new age.Dual transgene expression by foamy virus vectors carrying an endogenous bidirectional promoter.
P2860
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P2860
In vivo selection of hematopoietic stem cells transduced at a low multiplicity-of-infection with a foamy viral MGMT(P140K) vector.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
In vivo selection of hematopoi ...... oamy viral MGMT(P140K) vector.
@en
type
label
In vivo selection of hematopoi ...... oamy viral MGMT(P140K) vector.
@en
prefLabel
In vivo selection of hematopoi ...... oamy viral MGMT(P140K) vector.
@en
P2093
P2860
P1476
In vivo selection of hematopoi ...... oamy viral MGMT(P140K) vector.
@en
P2093
Aaron Ernstberger
Anthony L Sinn
Barbara J Bailey
Haiyan Wang
Helmut Hanenberg
Jennifer R Hartwell
Olaf Eckermann
Shanbao Cai
W Scott Goebel
Yvonne Linka
P2860
P304
P356
10.1016/J.EXPHEM.2007.11.009
P577
2008-03-01T00:00:00Z