Induction of p53 in mouse cells decreases mutagenesis by UV radiation.
about
p53-mediated protective responses to UV irradiation.p53 and c-Jun functionally synergize in the regulation of the DNA repair gene hMSH2 in response to UV.The p53 tumor suppressor protein reduces point mutation frequency of a shuttle vector modified by the chemical mutagens (+/-)7, 8-dihydroxy-9,10-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene, aflatoxin B1 and meta-chloroperoxybenzoic acid.Sticky DNA formation in vivo alters the plasmid dimer/monomer ratio.Mdm2 sensitizes MCF7 breast cancer cells to cisplatin or carboplatin.Inhibition of cyclobutane pyrimidine dimer formation in epidermal p53 gene of UV-irradiated mice by alpha-tocopherol.
P2860
Induction of p53 in mouse cells decreases mutagenesis by UV radiation.
description
1995 nî lūn-bûn
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1995年の論文
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1995年学术文章
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1995年学术文章
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1995年学术文章
@zh-hans
1995年学术文章
@zh-my
1995年学术文章
@zh-sg
1995年學術文章
@yue
1995年學術文章
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1995年學術文章
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name
Induction of p53 in mouse cells decreases mutagenesis by UV radiation.
@en
type
label
Induction of p53 in mouse cells decreases mutagenesis by UV radiation.
@en
prefLabel
Induction of p53 in mouse cells decreases mutagenesis by UV radiation.
@en
P2093
P356
P1433
P1476
Induction of p53 in mouse cells decreases mutagenesis by UV radiation.
@en
P2093
P304
P356
10.1093/CARCIN/16.10.2295
P407
P577
1995-10-01T00:00:00Z