Exome sequencing identifies mutation in CNOT3 and ribosomal genes RPL5 and RPL10 in T-cell acute lymphoblastic leukemia. - Wikidata - awgldk - TriplyDB

Exome sequencing identifies mutation in CNOT3 and ribosomal genes RPL5 and RPL10 in T-cell acute lymphoblastic leukemia.

Exome sequencing identifies mutation in CNOT3 and ribosomal genes RPL5 and RPL10 in T-cell acute lymphoblastic leukemia.

http://www.wikidata.org/entity/Q41296537

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Pathways to Specialized Ribosomes: The Brussels Lecture Ribosomopathies: how a common root can cause a tree of pathologies Diagnosis and subclassification of acute lymphoblastic leukemia Mutational signatures: the patterns of somatic mutations hidden in cancer genomes Redefining ALL classification: toward detecting high-risk ALL and implementing precision medicine Mechanism of eIF6 release from the nascent 60S ribosomal subunit.Diverse diseases from a ubiquitous process: the ribosomopathy paradox Role of ribosomal protein mutations in tumor development (Review)Targeted sequencing identifies associations between IL7R-JAK mutations and epigenetic modulators in T-cell acute lymphoblastic leukemia Use of single nucleotide polymorphism array technology to improve the identification of chromosomal lesions in leukemia Reprogramming the genetic code: The emerging role of ribosomal frameshifting in regulating cellular gene expression Efforts to make and apply humanized yeast Signatures of mutational processes in human cancer A Ribosomopathy Reveals Decoding Defective Ribosomes Driving Human Dysmorphism Data on affected cancer-related genes in pediatric t(12;21)-positive acute lymphoblastic leukemia patients harboring unbalanced der(6)t(X;6) translocations.Mutations in epigenetic regulators including SETD2 are gained during relapse in paediatric acute lymphoblastic leukaemia Mechanisms of genome instability induced by RNA-processing defects.Mutations in the NOT Genes or in the Translation Machinery Similarly Display Increased Resistance to Histidine Starvation The H3K27me3 demethylase UTX in normal development and disease.Cooperative down-regulation of ribosomal protein L10 and NF-κB signaling pathway is responsible for the anti-proliferative effects by DMAPT in pancreatic cancer cells DOTS-Finder: a comprehensive tool for assessing driver genes in cancer genomes.Altered translation of GATA1 in Diamond-Blackfan anemia.Genome-wide mapping and characterization of Notch-regulated long noncoding RNAs in acute leukemia.Multifunctional roles of the mammalian CCR4-NOT complex in physiological phenomena.The emerging importance of ribosomal dysfunction in the pathogenesis of hematologic disorders.Deletion of L4 domains reveals insights into the importance of ribosomal protein extensions in eukaryotic ribosome assembly.Marrow failure: a window into ribosome biology Ribosomopathies and the paradox of cellular hypo- to hyperproliferation.Ribosomal proteins: functions beyond the ribosome The chromatin regulator Brpf1 regulates embryo development and cell proliferation Low expression of T-cell transcription factor BCL11b predicts inferior survival in adult standard risk T-cell acute lymphoblastic leukemia patients Differential Stoichiometry among Core Ribosomal Proteins Growth factor independent-1 maintains Notch1-dependent transcriptional programming of lymphoid precursors.Comprehensive analysis of transcriptome variation uncovers known and novel driver events in T-cell acute lymphoblastic leukemia Ectopic TLX1 expression accelerates malignancies in mice deficient in DNA-PK.The H3K27me3 demethylase UTX is a gender-specific tumor suppressor in T-cell acute lymphoblastic leukemia Ribosomal frameshifting in the CCR5 mRNA is regulated by miRNAs and the NMD pathway.Deep sequencing and SNP array analyses of pediatric T-cell acute lymphoblastic leukemia reveal NOTCH1 mutations in minor subclones and a high incidence of uniparental isodisomies affecting CDKN2A Mutational spectrum of adult T-ALL Ribosomal Protein Mutations Result in Constitutive p53 Protein Degradation through Impairment of the AKT Pathway

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Exome sequencing identifies mutation in CNOT3 and ribosomal genes RPL5 and RPL10 in T-cell acute lymphoblastic leukemia.

http://www.wikidata.org/entity/Q41296537

description

2012 nî lūn-bûn

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2012年の論文

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2012年学术文章

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2012年学术文章

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2012年学术文章

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2012年学术文章

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2012年学术文章

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2012年學術文章

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2012年學術文章

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2012年學術文章

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name

Exome sequencing identifies mu ...... acute lymphoblastic leukemia.

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Exome sequencing identifies mu ...... acute lymphoblastic leukemia.

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Exome sequencing identifies mu ...... acute lymphoblastic leukemia.

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Nature Genetics

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Exome sequencing identifies mu ...... acute lymphoblastic leukemia.

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Anne Uyttebroeck

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Arlen W Johnson

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Barbara Cauwelier

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Bram Sweron

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Carmen Vicente

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Ellen Geerdens

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Emmanuelle Clappier

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Hilde Vranckx

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Idoya Lahortiga

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Iwona Wlodarska

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P2860

The genetic basis of early T-cell precursor acute lymphoblastic leukaemia.

Fast and accurate short read alignment with Burrows-Wheeler transform

Alterations of the Notch pathway in lung cancer.

Analysis of the chronic lymphocytic leukemia coding genome: role of NOTCH1 mutational activation.

Somatic SF3B1 mutation in myelodysplasia with ring sideroblasts

Defining the pathway of cytoplasmic maturation of the 60S ribosomal subunit.

A genome-wide transgenic RNAi library for conditional gene inactivation in Drosophila

Exome sequencing identifies recurrent mutations of the splicing factor SF3B1 gene in chronic lymphocytic leukemia

Deletion of KDM6A, a histone demethylase interacting with MLL2, in three patients with Kabuki syndrome

High accuracy mutation detection in leukemia on a selected panel of cancer genes

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10.1038/NG.2508

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2

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Zeynep Kalender Atak

Peter Vandenberghe

Tiziana Girardi

Kim De Keersmaecker

Gert Hulselmans

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2012-12-23T00:00:00Z

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233976577

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1023820822

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