Mechanisms of topoisomerase I inhibition by anticancer drugs.
about
Review of systemic therapies for locally advanced and metastatic rectal cancerEffects of the combination of camptothecin and doxorubicin or etoposide on rat glioma cells and camptothecin-resistant variantsIdentification of the aminocatechol A-3253 as an in vitro poison of DNA topoisomerase I from Candida albicansTherapeutic activity of CPT-11, a DNA-topoisomerase I inhibitor, against peripheral primitive neuroectodermal tumour and neuroblastoma xenograftsIron chelators with topoisomerase-inhibitory activity and their anticancer applications.Nitric oxide inhibits topoisomerase II activity and induces resistance to topoisomerase II-poisons in human tumor cells.Induction of topoisomerase I cleavage complexes by 1-beta -D-arabinofuranosylcytosine (ara-C) in vitro and in ara-C-treated cells.A eukaryotic enzyme that can disjoin dead-end covalent complexes between DNA and type I topoisomerases.Differential expression of topoisomerase I and RAD52 protein in yeast reveals new facets of the mechanism of action of bisdioxopiperazine compounds.In the presence of subunit A inhibitors DNA gyrase cleaves DNA fragments as short as 20 bp at specific sites.Discovery of DNA Topoisomerase I Inhibitors with Low-Cytotoxicity Based on Virtual Screening from Natural Products.Nitric oxide inhibits ATPase activity and induces resistance to topoisomerase II-poisons in human MCF-7 breast tumor cells.Synergistic enhancement of topotecan-induced cell death by ascorbic acid in human breast MCF-7 tumor cells.
P2860
Q27021105-38A29FB8-87F1-457B-8608-E43EDEF162C8Q28361246-4F1D2C9A-801B-43D5-A0BD-E76FA0E17639Q28368205-B9A81562-9F1D-48F2-8714-BEE633D0F141Q28379054-A3FBCBB4-ADCD-480B-9FCD-145B59E54015Q36568915-1C6CF7FD-6974-49CC-AE6D-15E11F85C3D8Q37008894-0D6ADB14-D0E4-4FD7-864A-B6C18DA8FCD8Q37121596-E419ABBC-AAEB-421F-94B6-0942E5C22AA7Q37257775-CD479595-24DB-41D0-8E45-A31F5B28FFFCQ38273585-267FBFCF-5909-495F-A320-7EB8DBCDCC09Q39718939-0DC1EF17-BE51-47B9-AB82-ADBFE44153B8Q41161962-AF2D009E-7ED6-4482-AF33-799220D369C5Q41682184-11AA3B0B-EFB9-4B04-B0CE-150D9496DFAAQ46273019-FA8E08DD-5B0F-4887-92A8-63F1D557754F
P2860
Mechanisms of topoisomerase I inhibition by anticancer drugs.
description
1994 nî lūn-bûn
@nan
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
1994年论文
@zh
1994年论文
@zh-cn
name
Mechanisms of topoisomerase I inhibition by anticancer drugs.
@en
type
label
Mechanisms of topoisomerase I inhibition by anticancer drugs.
@en
prefLabel
Mechanisms of topoisomerase I inhibition by anticancer drugs.
@en
P2093
P1476
Mechanisms of topoisomerase I inhibition by anticancer drugs
@en
P2093
P577
1994-01-01T00:00:00Z