A growth hormone agonist produced by targeted mutagenesis at binding site 1. Evidence that site 1 regulates bioactivity.
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Functional growth hormone (GH) receptors and GH are expressed by preimplantation mouse embryos: a role for GH in early embryogenesis?ELISA for Determination of Human Growth Hormone: Recognition of Helix 4 EpitopesA long-acting, mono-PEGylated human growth hormone analog is a potent stimulator of weight gain and bone growth in hypophysectomized rats.Novel recombinant analogues of bovine placental lactogen. G133K and G133R provide a tool to understand the difference between the action of prolactin and growth hormone receptors.Computational stabilization of human growth hormone.Growth hormone (GH)-independent dimerization of GH receptor by a leucine zipper results in constitutive activation.The binding between the stem regions of human growth hormone (GH) receptor compensates for the weaker site 1 binding of 20-kDa human GH (hGH) than that of 22-kDa hGH.Activation of chimeric and full-length growth hormone receptors by growth hormone receptor monoclonal antibodies. A specific conformational change may be required for full-length receptor signaling.Aspartate 171 is the major primate-specific determinant of human growth hormone. Engineering porcine growth hormone to activate the human receptor.Conformational changes required in the human growth hormone receptor for growth hormone signaling.Activating mechanism of CNTF and related cytokines.Imaging IGF-I uptake in growth plate cartilage using in vivo multiphoton microscopy.20-kDa placental hGH-V has diminished diabetogenic and lactogenic activities compared with 22-kDa hGH-N while retaining antilipogenic activity.
P2860
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P2860
A growth hormone agonist produced by targeted mutagenesis at binding site 1. Evidence that site 1 regulates bioactivity.
description
1995 nî lūn-bûn
@nan
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
1995年论文
@zh
1995年论文
@zh-cn
name
A growth hormone agonist produ ...... site 1 regulates bioactivity.
@en
type
label
A growth hormone agonist produ ...... site 1 regulates bioactivity.
@en
prefLabel
A growth hormone agonist produ ...... site 1 regulates bioactivity.
@en
P2093
P2860
P356
P1476
A growth hormone agonist produ ...... site 1 regulates bioactivity.
@en
P2093
Bastiras S
Brinkworth R
Rowlinson SW
P2860
P304
16833-16839
P356
10.1074/JBC.270.28.16833
P407
P577
1995-07-01T00:00:00Z