Evidence for a thymus-dependent form of tolerance that is not based on elimination or anergy of reactive T cells.
about
Activation of human CD4+ cells with CD3 and CD46 induces a T-regulatory cell 1 phenotypeNeuroprotective autoimmunity: naturally occurring CD4+CD25+ regulatory T cells suppress the ability to withstand injury to the central nervous system.The thymus contains a high frequency of cells that prevent autoimmune diabetes on transfer into prediabetic recipientsRegulatory T cells: mechanisms of differentiation and functionWhy Aire? Compensating for late bloomers.Grafts of supplementary thymuses injected with allogeneic pancreatic islets protect nonobese diabetic mice against diabetes.Foxp3+ CD25- CD4 T cells constitute a reservoir of committed regulatory cells that regain CD25 expression upon homeostatic expansion.Human CD4(+)CD25(+) thymocytes and peripheral T cells have immune suppressive activity in vitro.T-cell regulation of peripheral tolerance and immunity: the potential role for Notch signalling.Specificity requirements for selection and effector functions of CD25+4+ regulatory T cells in anti-myelin basic protein T cell receptor transgenic mice.How specificity for self-peptides shapes the development and function of regulatory T cells.Selection of Foxp3+ regulatory T cells specific for self antigen expressed and presented by Aire+ medullary thymic epithelial cells.Lineage stability and phenotypic plasticity of Foxp3⁺ regulatory T cells.In vivo dynamics of antigen-specific regulatory T cells not predicted from behavior in vitroRegulatory T cells for tolerance therapy: revisiting the concept.Hematopoietic chimerism and transplantation tolerance: a role for regulatory T cells.Abnormal T cell selection on nod thymic epithelium is sufficient to induce autoimmune manifestations in C57BL/6 athymic nude mice.Failure to censor forbidden clones of CD4 T cells in autoimmune diabetes.Gene dosage--limiting role of Aire in thymic expression, clonal deletion, and organ-specific autoimmunity.On the role of thymic epithelium vs. bone marrow-derived cells in repertoire selection of T cells.Role of TCR specificity in CD4+ CD25+ regulatory T-cell selection.Molecular signature of recent thymic selection events on effector and regulatory CD4+ T lymphocytes.Agonist ligands expressed by thymic epithelium enhance positive selection of regulatory T lymphocytes from precursors with a normally diverse TCR repertoire.Determination of thymic function directly from peripheral blood: a validated modification to an established method.Heterogeneity of natural Foxp3+ T cells: a committed regulatory T-cell lineage and an uncommitted minor population retaining plasticityOn the critique by Colin Anderson of 'A reply to Dembic: on an end to the beginning of mis-understanding the immune response'.AHR Activation Is Protective against Colitis Driven by T Cells in Humanized MiceHow studies on the avian embryo have opened new avenues in the understanding of development: a view about the neural and hematopoietic systems.Thoughts engendered by Bretscher's Two-step, Two-signal model for a peripheral self-non-self discrimination and the origin of primer effector T helpers.A current perspective on cancer immune therapy: step-by-step approach to constructing the magic bulletRegulatory cells in health and disease.Transient depletion of dividing T lymphocytes in mice induces the emergence of regulatory T cells and dominant tolerance to islet allografts.Immunological tolerance 50 years after the Burnet Nobel Prize.Promiscuous gene expression in medullary thymic epithelial cells mirrors the peripheral self.
P2860
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P2860
Evidence for a thymus-dependent form of tolerance that is not based on elimination or anergy of reactive T cells.
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年学术文章
@wuu
1996年学术文章
@zh-cn
1996年学术文章
@zh-hans
1996年学术文章
@zh-my
1996年学术文章
@zh-sg
1996年學術文章
@yue
1996年學術文章
@zh
1996年學術文章
@zh-hant
name
Evidence for a thymus-dependen ...... or anergy of reactive T cells.
@en
type
label
Evidence for a thymus-dependen ...... or anergy of reactive T cells.
@en
prefLabel
Evidence for a thymus-dependen ...... or anergy of reactive T cells.
@en
P2093
P2860
P1476
Evidence for a thymus-dependen ...... or anergy of reactive T cells.
@en
P2093
Bandeira A
Coutinho A
Le Douarin N
Modigliani Y
Thomas-Vaslin V
P2860
P356
10.1111/J.1600-065X.1996.TB00898.X
P577
1996-02-01T00:00:00Z