Glucagon-like peptide I increases cytoplasmic calcium in insulin-secreting beta TC3-cells by enhancement of intracellular calcium mobilization.
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Stimulation of cloned human glucagon-like peptide 1 receptor expressed in HEK 293 cells induces cAMP-dependent activation of calcium-induced calcium releaseA novel lipid-anchored A-kinase Anchoring Protein facilitates cAMP-responsive membrane eventsGlucagon-like peptide-1 mobilizes intracellular Ca2+ and stimulates mitochondrial ATP synthesis in pancreatic MIN6 beta-cellsEpac: A new cAMP-binding protein in support of glucagon-like peptide-1 receptor-mediated signal transduction in the pancreatic beta-cellPancreatic regulation of glucose homeostasiscAMP-dependent mobilization of intracellular Ca2+ stores by activation of ryanodine receptors in pancreatic beta-cells. A Ca2+ signaling system stimulated by the insulinotropic hormone glucagon-like peptide-1-(7-37)Expression of cAMP-regulated guanine nucleotide exchange factors in pancreatic beta-cells.cAMP-regulated guanine nucleotide exchange factor II (Epac2) mediates Ca2+-induced Ca2+ release in INS-1 pancreatic beta-cellsFunctional ryanodine receptors in the plasma membrane of RINm5F pancreatic beta-cellsNew insights concerning the glucose-dependent insulin secretagogue action of glucagon-like peptide-1 in pancreatic beta-cells.Insulinotropic toxins as molecular probes for analysis of glucagon-likepeptide-1 receptor-mediated signal transduction in pancreatic beta-cells.A novel dual-color reporter for identifying insulin-producing beta-cells and classifying heterogeneity of insulinoma cell linesExpression and function of pancreatic beta-cell delayed rectifier K+ channels. Role in stimulus-secretion coupling.PKA-dependent and PKA-independent pathways for cAMP-regulated exocytosis.NFAT targets signaling molecules to gene promoters in pancreatic β-cells.GLP-1 stimulates insulin secretion by PKC-dependent TRPM4 and TRPM5 activation.SUR1 regulates PKA-independent cAMP-induced granule priming in mouse pancreatic B-cellsRegulation of Glucokinase by Intracellular Calcium Levels in Pancreatic β CellsBeta-cell failure as a complication of diabetes.In situ activation of the type 2 ryanodine receptor in pancreatic beta cells requires cAMP-dependent phosphorylation.Ca(2+) channels on the move.A role of PLC/PKC-dependent pathway in GLP-1-stimulated insulin secretion.Heterogeneity of the Pancreatic Beta CellAmplification of exocytosis by Ca2+-induced Ca2+ release in INS-1 pancreatic beta cells.Secretagogue-dependent phosphorylation of the insulin granule membrane protein phogrin is mediated by cAMP-dependent protein kinase.Signal transduction of PACAP and GLP-1 in pancreatic beta cells.Glucose stimulates voltage- and calcium-dependent inositol trisphosphate production and intracellular calcium mobilization in insulin-secreting beta TC3 cells.cAMP-secretion coupling is impaired in diabetic GK/Par rat β-cells: a defect counteracted by GLP-1.Desensitization of glucagon-like peptide 1 receptors in insulin-secreting beta TC3 cells: role of PKA-independent mechanisms.Epac2-dependent mobilization of intracellular Ca²+ by glucagon-like peptide-1 receptor agonist exendin-4 is disrupted in β-cells of phospholipase C-ε knockout mice.Calcium-activated and voltage-gated potassium channels of the pancreatic islet impart distinct and complementary roles during secretagogue induced electrical responses.Thiol oxidation by 2,2'-dithiodipyridine causes a reversible increase in cytoplasmic free Ca2+ concentration in pancreatic beta-cells. Role for inositol 1,4,5-trisphosphate-sensitive Ca2+ stores.A cAMP and Ca2+ coincidence detector in support of Ca2+-induced Ca2+ release in mouse pancreatic beta cells.Glucagon-like peptide-1 induces a cAMP-dependent increase of [Na+]i associated with insulin secretion in pancreatic beta-cells.Pancreatic β-Cell Electrical Activity and Insulin Secretion: Of Mice and Men.β-Cell signalling and insulin secretagogues: A path for improved diabetes therapy.Glucagon-like peptide-1 receptor expression in Xenopus oocytes stimulates inositol trisphosphate-dependent intracellular Ca2+ mobilization.Inhibition of voltage-dependent potassium channels mediates cAMP-potentiated insulin secretion in rat pancreatic β cells.
P2860
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P2860
Glucagon-like peptide I increases cytoplasmic calcium in insulin-secreting beta TC3-cells by enhancement of intracellular calcium mobilization.
description
1995 nî lūn-bûn
@nan
1995年の論文
@ja
1995年学术文章
@wuu
1995年学术文章
@zh-cn
1995年学术文章
@zh-hans
1995年学术文章
@zh-my
1995年学术文章
@zh-sg
1995年學術文章
@yue
1995年學術文章
@zh
1995年學術文章
@zh-hant
name
Glucagon-like peptide I increa ...... cellular calcium mobilization.
@en
type
label
Glucagon-like peptide I increa ...... cellular calcium mobilization.
@en
prefLabel
Glucagon-like peptide I increa ...... cellular calcium mobilization.
@en
P2093
P356
P1433
P1476
Glucagon-like peptide I increa ...... cellular calcium mobilization.
@en
P2093
Frøkjaer-Jensen J
Renström E
P304
P356
10.2337/DIAB.44.7.767
P407
P577
1995-07-01T00:00:00Z