Three suppressor mutations which cure a mitochondrial RNA maturase deficiency occur at the same codon in the open reading frame of the nuclear NAM2 gene.
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Replacement of two non-adjacent amino acids in the S.cerevisiae bi2 intron-encoded RNA maturase is sufficient to gain a homing-endonuclease activityThe Cbp2 protein stimulates the splicing of the omega intron of yeast mitochondria.Genetic evidence for interaction between Cbp1 and specific nucleotides in the 5' untranslated region of mitochondrial cytochrome b mRNA in Saccharomyces cerevisiae.An inserted region of leucyl-tRNA synthetase plays a critical role in group I intron splicing.Maturase and endonuclease functions depend on separate conserved domains of the bifunctional protein encoded by the group I intron aI4 alpha of yeast mitochondrial DNA.An essential yeast protein, encoded by duplicated genes TIF1 and TIF2 and homologous to the mammalian translation initiation factor eIF-4A, can suppress a mitochondrial missense mutationCloning and expression of a mammalian peptide chain release factor with sequence similarity to tryptophanyl-tRNA synthetasesSequence and structural similarities between the leucine-specific binding protein and leucyl-tRNA synthetase of Escherichia coli.Efficient splicing of two yeast mitochondrial introns controlled by a nuclear-encoded maturaseA C-terminal fragment of an intron-encoded maturase is sufficient for promoting group I intron splicingThe rad18 gene of Schizosaccharomyces pombe defines a new subgroup of the SMC superfamily involved in DNA repair.Leucyl-tRNA synthetase-dependent and -independent activation of a group I intronA prokaryote and human tRNA synthetase provide an essential RNA splicing function in yeast mitochondria.Solution conformation of several free tRNALeu species from bean, yeast and Escherichia coli and interaction of these tRNAs with bean cytoplasmic Leucyl-tRNA synthetase. A phosphate alkylation study with ethylnitrosourea.Yeast mitochondrial leucyl-tRNA synthetase CP1 domain has functionally diverged to accommodate RNA splicing at expense of hydrolytic editing.The NAM2 proteins from S. cerevisiae and S. douglasii are mitochondrial leucyl-tRNA synthetases, and are involved in mRNA splicing.Cotranscriptional splicing of a group I intron is facilitated by the Cbp2 protein.Involvement of tyrosyl-tRNA synthetase in splicing of group I introns in Neurospora crassa mitochondria: biochemical and immunochemical analyses of splicing activity.Autocatalytic activities of intron 5 of the cob gene of yeast mitochondria.Nuclear gene for mitochondrial leucyl-tRNA synthetase of Neurospora crassa: isolation, sequence, chromosomal mapping, and evidence that the leu-5 locus specifies structural information.PET genes of Saccharomyces cerevisiae.The nuclear SUV3-1 mutation affects a variety of post-transcriptional processes in yeast mitochondria.The self-splicing intron in the Neurospora apocytochrome b gene contains a long reading frame in frame with the upstream exon.Molecular cloning and nucleotide sequence of the gene for Escherichia coli leucyl-tRNA synthetase.Human mitochondrial leucyl tRNA synthetase can suppress non cognate pathogenic mt-tRNA mutations
P2860
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P2860
Three suppressor mutations which cure a mitochondrial RNA maturase deficiency occur at the same codon in the open reading frame of the nuclear NAM2 gene.
description
1987 nî lūn-bûn
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1987年の論文
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1987年学术文章
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1987年学术文章
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1987年学术文章
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1987年学术文章
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1987年学术文章
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1987年學術文章
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1987年學術文章
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1987年學術文章
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name
Three suppressor mutations whi ...... rame of the nuclear NAM2 gene.
@en
type
label
Three suppressor mutations whi ...... rame of the nuclear NAM2 gene.
@en
prefLabel
Three suppressor mutations whi ...... rame of the nuclear NAM2 gene.
@en
P2093
P2860
P1433
P1476
Three suppressor mutations whi ...... rame of the nuclear NAM2 gene.
@en
P2093
Dujardin G
Herbert CJ
Labouesse M
Slonimski PP
P2860
P304
P407
P577
1987-03-01T00:00:00Z