Carboxyl-terminal prodomain-deleted human leukocyte elastase and cathepsin G are efficiently targeted to granules and enzymatically activated in the rat basophilic/mast cell line RBL.
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Contributions to neutropenia from PFAAP5 (N4BP2L2), a novel protein mediating transcriptional repressor cooperation between Gfi1 and neutrophil elastaseThe Role of Serine Proteases and Antiproteases in the Cystic Fibrosis Lungα1Proteinase inhibitor regulates CD4+ lymphocyte levels and is rate limiting in HIV-1 diseaseNeutrophil elastase, proteinase 3, and cathepsin G as therapeutic targets in human diseases.Activation of the unfolded protein response is associated with impaired granulopoiesis in transgenic mice expressing mutant Elane.Neutrophil elastase in cyclic and severe congenital neutropenia.Pathogenesis of ELANE-mutant severe neutropenia revealed by induced pluripotent stem cellsComplementary LC-MS/MS-Based N-Glycan, N-Glycopeptide, and Intact N-Glycoprotein Profiling Reveals Unconventional Asn71-Glycosylation of Human Neutrophil Cathepsin G.Neutropenia-associated ELANE mutations disrupting translation initiation produce novel neutrophil elastase isoforms.Granule protein processing and regulated secretion in neutrophils.Role of loop structures of neuropsin in the activity of serine protease and regulated secretion.Cathepsin G induces cell aggregation of human breast cancer MCF-7 cells via a 2-step mechanism: catalytic site-independent binding to the cell surface and enzymatic activity-dependent induction of the cell aggregation.Paucimannose-Rich N-glycosylation of Spatiotemporally Regulated Human Neutrophil Elastase Modulates Its Immune Functions.Proteinase-3, a serine protease which mediates doxorubicin-induced apoptosis in the HL-60 leukemia cell line, is downregulated in its doxorubicin-resistant variant.The role of the propeptide for processing and sorting of human myeloperoxidase.Leishmania inhibitor of serine peptidase 2 prevents TLR4 activation by neutrophil elastase promoting parasite survival in murine macrophages.Characterization of mutant neutrophil elastase in severe congenital neutropenia.Apoptosis-induced proteinase 3 membrane expression is independent from degranulation.Reconstitution of human azurocidin catalytic triad and proteolytic activity by site-directed mutagenesis.
P2860
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P2860
Carboxyl-terminal prodomain-deleted human leukocyte elastase and cathepsin G are efficiently targeted to granules and enzymatically activated in the rat basophilic/mast cell line RBL.
description
1995 nî lūn-bûn
@nan
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
1995年论文
@zh
1995年论文
@zh-cn
name
Carboxyl-terminal prodomain-de ...... basophilic/mast cell line RBL.
@en
type
label
Carboxyl-terminal prodomain-de ...... basophilic/mast cell line RBL.
@en
prefLabel
Carboxyl-terminal prodomain-de ...... basophilic/mast cell line RBL.
@en
P2093
P2860
P356
P1476
Carboxyl-terminal prodomain-de ...... basophilic/mast cell line RBL.
@en
P2093
P2860
P304
12912-12918
P356
10.1074/JBC.270.21.12912
P407
P577
1995-05-01T00:00:00Z