CRISPR/Cas9-Mediated Deletion of Foxn1 in NOD/SCID/IL2rg-/- Mice Results in Severe Immunodeficiency.

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Modeling the human bone marrow niche in mice: From host bone marrow engraftment to bioengineering approaches.Bacterial and Pneumocystis Infections in the Lungs of Gene-Knockout Rabbits with Severe Combined Immunodeficiency.

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P2860

CRISPR/Cas9-Mediated Deletion of Foxn1 in NOD/SCID/IL2rg-/- Mice Results in Severe Immunodeficiency.

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http://www.wikidata.org/entity/Q41353519

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2017 nî lūn-bûn

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2017年の論文

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2017年論文

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2017年論文

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2017年論文

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2017年论文

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name

CRISPR/Cas9-Mediated Deletion ...... ts in Severe Immunodeficiency.

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CRISPR/Cas9-Mediated Deletion ...... ts in Severe Immunodeficiency.

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CRISPR/Cas9-Mediated Deletion ...... ts in Severe Immunodeficiency.

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P1476

CRISPR/Cas9-Mediated Deletion ...... lts in Severe Immunodeficiency

@en

P2093

Baiheng Li

http://www.w3.org/2001/XMLSchema#string

Donghai Wu

http://www.w3.org/2001/XMLSchema#string

Guohua Huang

http://www.w3.org/2001/XMLSchema#string

Le Qin

http://www.w3.org/2001/XMLSchema#string

Liangxue Lai

http://www.w3.org/2001/XMLSchema#string

Pentao Liu

http://www.w3.org/2001/XMLSchema#string

Qiting Wu

http://www.w3.org/2001/XMLSchema#string

Qiubin Liang

http://www.w3.org/2001/XMLSchema#string

Qiuhua Deng

http://www.w3.org/2001/XMLSchema#string

Simiao Lin

http://www.w3.org/2001/XMLSchema#string

P2860

Multiplex genome engineering using CRISPR/Cas systems

Unified nomenclature for the winged helix/forkhead transcription factors

NOD/SCID/gamma(c)(null) mouse: an excellent recipient mouse model for engraftment of human cells

A severe combined immunodeficiency mutation in the mouse

Foxn1 regulates lineage progression in cortical and medullary thymic epithelial cells but is dispensable for medullary sublineage divergence

RAG-1-deficient mice have no mature B and T lymphocytes

RAG-2-deficient mice lack mature lymphocytes owing to inability to initiate V(D)J rearrangement

Foxn1 is required to maintain the postnatal thymic microenvironment in a dosage-sensitive manner

One-step generation of mice carrying mutations in multiple genes by CRISPR/Cas-mediated genome engineering

Postnatal tissue-specific disruption of transcription factor FoxN1 triggers acute thymic atrophy.

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s41598-017-08337-8

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scholarly article

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10.1038/S41598-017-08337-8

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English

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Peng Li

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2017-08-10T00:00:00Z

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28798321

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CRISPR

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5552779

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CRISPR/Cas9-Mediated Deletion of Foxn1 in NOD/SCID/IL2rg-/- Mice Results in Severe Immunodeficiency.

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P2860

P2860

CRISPR/Cas9-Mediated Deletion of Foxn1 in NOD/SCID/IL2rg-/- Mice Results in Severe Immunodeficiency.

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type

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P1476

P2093

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