Monoclonal antibodies that block the activity of leukocyte function-associated antigen 1 recognize three discrete epitopes in the inserted domain of CD11a.
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Crystal structure of the alpha1beta1 integrin I-domain: insights into integrin I-domain functionEfalizumab binding to the LFA-1 L I domain blocks ICAM-1 binding via steric hindranceCrystal structure of the I domain from integrin alpha2beta1A binding interface on the I domain of lymphocyte function-associated antigen-1 (LFA-1) required for specific interaction with intercellular adhesion molecule 1 (ICAM-1)Antibodies against thrombospondin-related anonymous protein do not inhibit Plasmodium sporozoite infectivity in vivoB-Raf regulation of integrin α4β1-mediated resistance to shear stress through changes in cell spreading and cytoskeletal association in T cellsLovastatin Inhibits Low Molecular Weight Hyaluronan Induced Chemokine Expression via LFA-1 and Decreases Bleomycin-Induced Pulmonary Fibrosis.Insights into integrin-ligand binding and activation from the first crystal structure.Folding of the beta-propeller domain of the integrin alphaL subunit is independent of the I domain and dependent on the beta2 subunit.Aggregatibacter actinomycetemcomitans leukotoxin requires beta-sheets 1 and 2 of the human CD11a beta-propeller for cytotoxicity.LFA-1-deficient mice show normal CTL responses to virus but fail to reject immunogenic tumor.Monoclonal antibodies to CD44 and their influence on hyaluronan recognition.Rotavirus contains integrin ligand sequences and a disintegrin-like domain that are implicated in virus entry into cells.NMR and mutagenesis evidence for an I domain allosteric site that regulates lymphocyte function-associated antigen 1 ligand binding.Critical amino acids in the lymphocyte function-associated antigen-1 I domain mediate intercellular adhesion molecule 3 binding and immune functionNMR characterization of the conformational fluctuations of the human lymphocyte function-associated antigen-1 I-domainIdentification of amino acids in the CD11a I-domain important for binding of the leukocyte function-associated antigen-1 (LFA-1) to intercellular adhesion molecule-1 (ICAM-1)Mapping the intercellular adhesion molecule-1 and -2 binding site on the inserted domain of leukocyte function-associated antigen-1.Antibodies That Selectively Inhibit Leukocyte Function-associated Antigen 1 Binding to Intercellular Adhesion Molecule-3 Recognize a Unique Epitope within the CD11a I Domain
P2860
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P2860
Monoclonal antibodies that block the activity of leukocyte function-associated antigen 1 recognize three discrete epitopes in the inserted domain of CD11a.
description
1995 nî lūn-bûn
@nan
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
1995年论文
@zh
1995年论文
@zh-cn
name
Monoclonal antibodies that blo ...... the inserted domain of CD11a.
@en
type
label
Monoclonal antibodies that blo ...... the inserted domain of CD11a.
@en
prefLabel
Monoclonal antibodies that blo ...... the inserted domain of CD11a.
@en
P2093
P2860
P356
P1476
Monoclonal antibodies that blo ...... the inserted domain of CD11a.
@en
P2093
P2860
P304
P356
10.1074/JBC.270.3.1388
P407
P577
1995-01-01T00:00:00Z