Interaction profiling identifies the human nuclear exosome targeting complex.
about
Exonuclease hDIS3L2 specifies an exosome-independent 3'-5' degradation pathway of human cytoplasmic mRNAMammalian DIS3L2 exoribonuclease targets the uridylated precursors of let-7 miRNAsAir2p is critical for the assembly and RNA-binding of the TRAMP complex and the KOW domain of Mtr4p is crucial for exosome activationThreading the barrel of the RNA exosomeSki2-like RNA helicase structures: common themes and complex assembliesNuclear noncoding RNA surveillance: is the end in sight?The Zinc-Finger Protein SOP1 Is Required for a Subset of the Nuclear Exosome Functions in ArabidopsisQuality control of spliced mRNAs requires the shuttling SR proteins Gbp2 and Hrb1.RNA unwinding by the Trf4/Air2/Mtr4 polyadenylation (TRAMP) complexThe role of TREX in gene expression and diseaseRNA Exosome Regulates AID DNA Mutator Activity in the B Cell GenomeSystematic E2 screening reveals a UBE2D-RNF138-CtIP axis promoting DNA repairPolyadenylation-dependent control of long noncoding RNA expression by the poly(A)-binding protein nuclear 1The RNA helicases AtMTR4 and HEN2 target specific subsets of nuclear transcripts for degradation by the nuclear exosome in Arabidopsis thalianaThe nuclear cap-binding complex interacts with the U4/U6·U5 tri-snRNP and promotes spliceosome assembly in mammalian cellsMutations in Mtr4 Structural Domains Reveal Their Important Role in Regulating tRNAiMet Turnover in Saccharomyces cerevisiae and Mtr4p Enzymatic Activities In Vitro.Inhibition of U4 snRNA in human cells causes the stable retention of polyadenylated pre-mRNA in the nucleus.Post-transcriptional regulation of meiotic genes by a nuclear RNA silencing complex.Certain adenylated non-coding RNAs, including 5' leader sequences of primary microRNA transcripts, accumulate in mouse cells following depletion of the RNA helicase MTR4Tailing and degradation of Argonaute-bound small RNAs protect the genome from uncontrolled RNAi.mRNA stability in the nucleus.Poly(A)-specific ribonuclease is a nuclear ribosome biogenesis factor involved in human 18S rRNA maturation.Progenitor function in self-renewing human epidermis is maintained by the exosome.Comparison of the yeast and human nuclear exosome complexes.A MicroRNA precursor surveillance system in quality control of MicroRNA synthesis.Emerging roles for ribonucleoprotein modification and remodeling in controlling RNA fateThe human nuclear poly(a)-binding protein promotes RNA hyperadenylation and decayp38MAPK/MK2-mediated phosphorylation of RBM7 regulates the human nuclear exosome targeting complexNab3 facilitates the function of the TRAMP complex in RNA processing via recruitment of Rrp6 independent of Nrd1Air1 zinc knuckles 4 and 5 and a conserved IWRXY motif are critical for the function and integrity of the Trf4/5-Air1/2-Mtr4 polyadenylation (TRAMP) RNA quality control complex.RBM7 subunit of the NEXT complex binds U-rich sequences and targets 3'-end extended forms of snRNAsRibonucleic acid (RNA) biosynthesis in human cancer.DeCoN: genome-wide analysis of in vivo transcriptional dynamics during pyramidal neuron fate selection in neocortex.Rapid, optimized interactomic screeningThe fission yeast MTREC complex targets CUTs and unspliced pre-mRNAs to the nuclear exosome.An Interaction between RRP6 and SU(VAR)3-9 Targets RRP6 to Heterochromatin and Contributes to Heterochromatin Maintenance in Drosophila melanogasterCanonical Poly(A) Polymerase Activity Promotes the Decay of a Wide Variety of Mammalian Nuclear RNAs.Oligoadenylation of 3' decay intermediates promotes cytoplasmic mRNA degradation in Drosophila cells.Maturation of mammalian H/ACA box snoRNAs: PAPD5-dependent adenylation and PARN-dependent trimmingDIS3 shapes the RNA polymerase II transcriptome in humans by degrading a variety of unwanted transcripts.
P2860
Q24294915-3C5C3008-E262-472C-94EC-40691BCC7A90Q24338738-E364C30A-6253-4944-8B77-D18D4EA20EF0Q24597353-6AE7860C-0A55-44EB-92AD-AC58F3F8AE38Q26851853-AF61F821-38AE-4A33-BDF0-89ABECE6FB75Q26852748-DAF3C004-1BB4-471D-A58F-DEA503B85C1BQ27026368-05AC27EA-1C50-4A08-BD10-E0D631FF0B4AQ27309189-2C2C78B1-55DA-4B93-B236-D40E665E47D7Q27929798-EEF17D46-14CB-4D74-A03E-3349CB72694CQ27934730-747B01C8-9E6C-4C43-A000-3C226F091603Q28078160-40ED060F-929A-481D-BD39-EA52AF204864Q28087424-381392DD-1FA0-45B3-BD07-56A9B656256DQ28115456-AF2E4BB6-EBCD-484D-9C9B-3355CCD2CF69Q28485193-CA8CDC17-6FCC-42B3-BB9A-E6AA1DB486E2Q28542463-6A060E2B-095E-4D16-8A0E-B1A4DE485A6CQ28910445-3D35EA0A-15AA-4A6C-B476-2CC5402B316BQ30383961-357A1942-DAE7-432C-BBD2-67FC868593ACQ33567881-06C6A12F-3CA6-47FE-A1B6-A7CF5A096F68Q33626243-0B2E83F7-C021-45BF-AE1B-27775BC52B86Q33753679-2D5D05E4-8093-4C9C-940C-74834D4F4BD4Q33762828-E9C9BEF1-CF9F-40AA-B41B-72FB124F8FF8Q33826916-5A3CC497-8BC5-446A-AC9E-CF85CDF30302Q33878723-F6228FD2-2ED5-4B30-A80B-745BABE25515Q34032685-1DF35571-B018-4FD5-A8AA-46E088E7B87FQ34032863-88F6B557-7BBA-40C8-8DF6-5609DFA52E25Q34217041-47ED2D98-BFDE-4C12-86BC-FBAEAAEECBF2Q34350089-AF2D4616-9449-40A6-A39D-0BD024107DB6Q35022339-3C66D6E7-5FF0-40EE-9C30-1A1495794474Q35113634-FBFAE47C-9968-4D2A-B086-364C6FC95D7FQ35182261-2F5A660D-D270-4A25-ACED-CABBC39F7543Q35423801-7408FC7A-41BE-461F-8C11-758B26D3FD20Q35562074-6316C633-0193-43FA-B42B-22ED99E8EBE9Q35567989-0A0EF4A8-F20F-4ABA-8644-9FC4D531A13DQ35602936-B7271A62-D3DD-417E-A8DC-BB0A1E033A30Q35665985-33D409C6-0D3A-4042-ADD0-9B1DF4E003C8Q35681747-D2E13AFE-177F-4964-93C6-303A6D94517DQ35781738-C71C670A-0C75-4F5C-9930-DE7BE6699B2CQ35814334-89E3E898-A766-44BA-A74F-D618F757E820Q35898390-4D2EEDEF-EA20-4FCB-8FE0-8FCBF4AE4524Q35907950-8DA0FD87-7D1F-4C4D-A57C-FB68F706705FQ36199560-513052AB-A705-4786-81E7-D5CB15943C17
P2860
Interaction profiling identifies the human nuclear exosome targeting complex.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Interaction profiling identifies the human nuclear exosome targeting complex.
@en
type
label
Interaction profiling identifies the human nuclear exosome targeting complex.
@en
prefLabel
Interaction profiling identifies the human nuclear exosome targeting complex.
@en
P2093
P921
P1433
P1476
Interaction profiling identifies the human nuclear exosome targeting complex.
@en
P2093
Jens S Andersen
Lasse G Falkenby
Maiken S Kristiansen
Marianne S Christensen
Michal Domanski
Michal Lubas
Torben Heick Jensen
P304
P356
10.1016/J.MOLCEL.2011.06.028
P577
2011-08-01T00:00:00Z