Reengineering a tryptophan halogenase to preferentially chlorinate a direct alkaloid precursor.
about
Genetically modified proteins: functional improvement and chimeragenesisRecent progress in the metabolic engineering of alkaloids in plant systemsImproving the Stability and Catalyst Lifetime of the Halogenase RebH By Directed EvolutionRegioselective arene halogenation using the FAD-dependent halogenase RebH.Directed evolution of RebH for site-selective halogenation of large biologically active molecules.Directed Evolution of RebH for Catalyst-Controlled Halogenation of Indole C-H BondsSpecific chlorination of isoquinolines by a fungal flavin-dependent halogenase.A polymorphic (GA/CT)n- SSR influences promoter activity of Tryptophan decarboxylase gene in Catharanthus roseus L. Don.Synthetic biological approaches to natural product biosynthesis.Natural products - modifying metabolite pathways in plants.Synthetic biology for the directed evolution of protein biocatalysts: navigating sequence space intelligently.Halogenase Engineering for the Generation of New Natural Product Analogues.Specific Enzymatic Halogenation-From the Discovery of Halogenated Enzymes to Their Applications In Vitro and In Vivo.Enzymatic Halogenation: A Timely Strategy for Regioselective C-H Activation.Regioselective Dichlorination of a Non-Activated Aliphatic Carbon Atom and Phenolic Bismethylation by a Multifunctional Fungal Flavoenzyme.Integrated catalysis opens new arylation pathways via regiodivergent enzymatic C-H activation.A high-throughput assay for arylamine halogenation based on a peroxidase-mediated quinone-amine coupling with applications in the screening of enzymatic halogenations.Artificial multi-enzyme networks for the asymmetric amination of sec-alcohols.Function and Structure of MalA/MalA', Iterative Halogenases for Late-Stage C-H Functionalization of Indole Alkaloids.Enantioselective Desymmetrization of Methylenedianilines via Enzyme-Catalyzed Remote Halogenation.Production of indole alkaloids by metabolic engineering of the tryptophan pathway in rice.Aromatic Halogenation by Using Bifunctional Flavin Reductase-Halogenase Fusion Enzymes.Accelerating the semisynthesis of alkaloid-based drugs through metabolic engineering.Extending the biocatalytic scope of regiocomplementary flavin-dependent halogenase enzymes.Understanding and Improving the Activity of Flavin-Dependent Halogenases via Random and Targeted Mutagenesis.Expanding beyond canonical metabolism: Interfacing alternative elements, synthetic biology, and metabolic engineering.Monoterpenoid indole alkaloids biosynthesis and its regulation in Catharanthus roseus: a literature review from genes to metabolitesTwo-Component FAD-Dependent Monooxygenases: Current Knowledge and Biotechnological Opportunities
P2860
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P2860
Reengineering a tryptophan halogenase to preferentially chlorinate a direct alkaloid precursor.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Reengineering a tryptophan hal ...... e a direct alkaloid precursor.
@en
type
label
Reengineering a tryptophan hal ...... e a direct alkaloid precursor.
@en
prefLabel
Reengineering a tryptophan hal ...... e a direct alkaloid precursor.
@en
P2093
P356
P1476
Reengineering a tryptophan hal ...... e a direct alkaloid precursor.
@en
P2093
Ezekiel Nims
Sarah E O'Connor
Weslee S Glenn
P304
19346-19349
P356
10.1021/JA2089348
P407
P577
2011-11-11T00:00:00Z