Tissue-specific targeting of retroviral vectors through ligand-receptor interactions.
about
BP1, a homeodomain-containing isoform of DLX4, represses the beta-globin geneTransfer of single gene-containing long terminal repeats into the genome of mammalian cells by a retroviral vector carrying the cre gene and the loxP siteEngineering fusogenic molecules to achieve targeted transduction of enveloped lentiviral vectorsMicrobead display by in vitro compartmentalisation: selection for binding using flow cytometry.Identification of FGF receptor-binding peptides for cancer gene therapy.Antibody-ribosome-mRNA (ARM) complexes as efficient selection particles for in vitro display and evolution of antibody combining sites.Enhanced nigrostriatal neuron-specific, long-term expression by using neural-specific promoters in combination with targeted gene transfer by modified helper virus-free HSV-1 vector particles.Molecular engineering of viral gene delivery vehiclesGene therapy and dermatology: more than just skin deep.Redirecting lentiviral vectors by insertion of integrin-tageting peptides into envelope proteins.A versatile targeting system with lentiviral vectors bearing the biotin-adaptor peptide.Strategy of liver-directed gene therapy: present status and future prospects.Tissue-specific expression of herpes simplex virus thymidine kinase gene delivered by adeno-associated virus inhibits the growth of human hepatocellular carcinoma in athymic mice.Tumor-targeted delivery of liposome-encapsulated doxorubicin by use of a peptide that selectively binds to irradiated tumors.Definition of a 14-amino-acid peptide essential for the interaction between the murine leukemia virus amphotropic envelope glycoprotein and its receptor.Evidence for cooperation between murine leukemia virus Env molecules in mixed oligomers.Recombinant herpes simplex virus type 1 engineered for targeted binding to erythropoietin receptor-bearing cells.A TVA-single-chain antibody fusion protein mediates specific targeting of a subgroup A avian leukosis virus vector to cells expressing a tumor-specific form of epidermal growth factor receptorSingle-step conversion of cells to retrovirus vector producers with herpes simplex virus-Epstein-Barr virus hybrid amplicons.The application of gene therapy in autoimmune diseases.Comprehensive mutational analysis of the Moloney murine leukemia virus envelope protein.Variations in disparate regions of the murine coronavirus spike protein impact the initiation of membrane fusion.Ligand-directed retroviral targeting of human breast cancer cells.Modifying the host range properties of retroviral vectors.Progress with retroviral gene vectors.Generation of targeted retroviral vectors by using single-chain variable fragment: an approach to in vivo gene delivery.Construction of retroviral vectors with improved safety, gene expression, and versatility.Receptor-mediated targeting of gene delivery vectors: insights from molecular mechanisms for improved vehicle design.Ligand-directed targeting of genes to the site of disease.Library screening and receptor-directed targeting of gammaretroviral vectors.Targeting lentiviral vectors to specific cell types in vivo.Cancer gene therapy.Mannosylated poly(beta-amino esters) for targeted antigen presenting cell immune modulation.Redirected infection of directly biotinylated recombinant adenovirus vectors through cell surface receptors and antigens.Retroviral membrane display of apoptotic effector moleculesRetroviral retargeting by envelopes expressing an N-terminal binding domain.Selective infection of human T-lymphotropic virus type 1 (HTLV-1)-infected cells by chimeric human immunodeficiency viruses containing HTLV-1 tax response elements in the long terminal repeat.Improvement of retroviral retargeting by using amino acid spacers between an additional binding domain and the N terminus of Moloney murine leukemia virus SU.Targeted infection of human cells via major histocompatibility complex class I molecules by Moloney murine leukemia virus-derived viruses displaying single-chain antibody fragment-envelope fusion proteins.Characterization of chimeras between the ecotropic Moloney murine leukemia virus and the amphotropic 4070A envelope proteins.
P2860
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P2860
Tissue-specific targeting of retroviral vectors through ligand-receptor interactions.
description
1994 nî lūn-bûn
@nan
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
1994年论文
@zh
1994年论文
@zh-cn
name
Tissue-specific targeting of retroviral vectors through ligand-receptor interactions.
@en
type
label
Tissue-specific targeting of retroviral vectors through ligand-receptor interactions.
@en
prefLabel
Tissue-specific targeting of retroviral vectors through ligand-receptor interactions.
@en
P2093
P356
P1433
P1476
Tissue-specific targeting of retroviral vectors through ligand-receptor interactions.
@en
P2093
P304
P356
10.1126/SCIENCE.7973726
P407
P577
1994-11-01T00:00:00Z